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More than 20 years ago an American research group released a spectacular idea that the red blood cell was capable of exporting the signaling molecule nitric oxide (NO) and by this mechanism participate in the classical physiological phenomenon known as hypoxic vasodilation, i.e. that our blood vessels automatically widen when oxygen levels become lower to ensure oxygen delivery to tissues (Jia Nature 1996).

We would like to welcome Annika Bolind Bågenholm to the Department of Learning, Informatics, Management and Ethics.

The survival rate among extremely preterm babies has greatly improved in Sweden, a country that offers top-class neonatal care, a study led from Karolinska Institutet published in the esteemed journal JAMA reports.

If a particular protein is missing during the fetal stage, no neurons develop that convey pain, temperature and itch, a study from Karolinska Institutet published in the journal Cell Reports shows. The discovery can eventually lead to new drugs for pain conditions.

Three researchers at Karolinska Institutet have been appointed Wallenberg Scholar in 2019: Ernest Arenas, Sten Linnarsson, and Randal S. Johnson. The researchers – among the foremost in their field in Sweden – receive SEK 18 million each from the Wallenberg Foundations in the form of a five-year grant for free research.

Researchers at Karolinska Institutet have traced the neurons that send projections to the medial prefrontal cortex in the mouse. The 3D location of the input neurons have been mapped throughout the brain.

Even premature babies carry anti-viral antibodies transferred from the mother, researchers at Karolinska Institutet in Sweden report in a paper on maternal antibodies in newborns, published in the journal Nature Medicine. The results should change our approach to infection sensitivity in newborns, they say.

Each year MedTech Magazine appoints the 100 persons who most affect and contribute to care, patients' health and the availability of medical technology to citizens and patients.

With the start of 2019, the Karolinska Genome Engineering facility (KGE) has opened its doors as a core facility for researchers from both within and outside of Karolinska Institutet and Karolinska University Hospital. The facility, led by Bernhard Schmierer, is located in Biomedicum 9B at the Department of Medical Biochemistry and Biophysics, and provides various gene editing services in cells.

PhD student Sara Causevic and researcher Helena Nordenstedt at the Department of Public Health Sciences and student Wiebke Mohr at the Department of Learning, Informatics, Management and Ethics started the Women in Global Health Sweden Chapter as a response to the Call to Action on Gender Equality.

Karolinska Institutet now facilitates for all educational programs to use digital examinations. Digital examinations are legally secure and efficient as well as allows for new possibilties for teachers and course administrators to develop the education programs.

Olov Andersson, docent at the Department of Cell and Molecular Biology at Karolinska Institutet, is the recipient of The Leif C. Groop award for outstanding research for his research in zebrafish that could lead to new treatments for diabetes. Awarded by the Lund University Diabetes Centre and sponsored by Novo Nordisk Sweden.

By applying gene analysis to individual cells from early mouse embryos, researchers at Karolinska Institutet in Sweden have discovered previously unknown cellular stages of fetal development from fertilised egg to living being. The study is published in the scientific journal Cell Reports.

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease. The results are important for affected patients but can also help scientists to understand other rare diagnoses.

Professor Sven-Erik Dahlén, IMM, participates in the co-ordination team of the IMI project 3TR that was recently approved for funding by the European Commission.

The workshop ”Build program logic models” for innovations in the programme Let the patients drive! Implementing patient-driven co-care innovations was held on February 12th.