Study debunks notion that C-section would increase risk of obesity in the child
Women who have C-sections are no more likely to have children who develop obesity than women who give birth naturally, according to a study by researchers at Karolinska Institutet in Sweden published in PLOS Medicine. The findings contradict several smaller studies that did find an association between C-sections and offspring obesity but did not consider the numerous maternal and prenatal factors that the researchers did in this study.
New Wallenberg Academy Fellows appointed at KI
Six of the 29 new Wallenberg Academy Fellows appointed in 2019 will conduct their groundbreaking research at Karolinska Institutet. The five-year grant is financed by the Knut and Alice Wallenberg Foundation to provide the young and talented researcher leaders with long-term research funding in Sweden.
High androgen levels during pregnancy increase the risk of PCOS for several generations
Daughters of women with polycystic ovarian syndrome (PCOS) are five times more likely to be diagnosed with PCOS as adults, and the generational transmission is driven by high androgen levels during pregnancy, researchers at Karolinska Institutet in Sweden report. Their results, which are based on register-based and clinical studies as well as transgenerational animal studies, are published in Nature Medicine.
Online CBT for fibromyalgia shows promise
Researchers at Karolinska Institutet have developed an online Cognitive Behavioural Therapy (CBT) programme for the difficult-to-treat pain syndrome fibromyalgia. In her doctoral thesis, Maria Hedman-Lagerlöf shows that patients who receive the treatment experience fewer symptoms and enjoy better quality of life.
High blood pressure in the emergency room predicts risk of cardiovascular disease
There is a strong correlation between high blood pressure in patients in the emergency room and an increased risk of future cardiovascular disease, researchers from KI report in a large registry study. Their conclusion is that blood-pressure measurements in the emergency room can be used as a tool for reducing morbidity and mortality rates through early preventive intervention.
New principle for activation of cancer genes discovered
Forskare har länge vetat att vissa gener kan vara cancerframkallande när de blir för aktiva, men exakt vad som händer inne i cellkärnan när cancern utvecklas har hittills varit ett mysterium. Forskare vid Karolinska Institutet har nu funnit en ny mekanism som gör vissa cancergener överaktiva. Resultaten, som publiceras i Nature Genetics, skapar förutsättningar för helt nya strategier att bekämpa cancer.
Pioneers met researchers of the future when KI held conferment ceremony
“Each of you have taken your own path and have done it your way. That reminds me of a classic song,” said Robert Harris before he burst into Frank Sinatra’s ‘My Way’ in a tribute to Karolinska Institutet’s new doctors. With his tenor reverberating across the Blue Hall in Stockholm City Hall, the vice-president of doctoral education elicited laughter and applauds during KI’s annual autumn conferment ceremony held on Friday.
A limited selection of recent publications in high impact journals where researchers from KI are main authors.
Genes predict tamoxifen treatment outcome in breast cancer
CYP2D6 Genotype Predicts Tamoxifen Discontinuation and Prognosis in Patients With Breast Cancer, He, W et al, Journal of Clinical Oncology, Dec. 2019.
Contact lens measures eye pressure after transplantation of insulin-secreting cells
Intraocular Pressure Monitoring Following Islet Transplantation to the Anterior Chamber of the Eye, Joohee Kim et al, Nano Letters, Nov 2019.
Increased neurogenesis in mice after fecal transplant
Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice, Kundu P et al, Science Translational Medicine, Nov 2019.
KI in the media
The Macchiarini case: timeline
Spotlight on prostate cancer
Many researchers agree that screening is a way to reduce mortality in prostate cancer patients, but so far the diagnostic methods have been inadequate. Find articles from the latest issue of our magazine Medicinsk Vetenskap translated to English.
On Thursday, 17 October 2019, thirteen new professors were inaugurated at Karolinska Institutet in solemn forms in Aula Medica. The professor's inauguration ceremony is one of the highlights of the academic year of our university.