The disappointment that led to a Nobel prize
When Nobel prize winner Michael Kremer initially looked at the data of his now famous 1990s Kenya school study, he felt shocked and disappointed. The data showed that more textbooks did nothing to improve educational outcomes, contrary to what most researchers believed. But rather than succumbing to disillusionment, Kremer dug deeper into Kenya’s schooling system to uncover what measures truly did make an impact and found his answer: targeted help for weak students. On Wednesday, he visited KI.
SEK 28 million from KAW to four KI researchers
Four researchers at Karolinska Institutet have been granted a total of SEK 28 million in additional funding from the Knut and Alice Wallenberg Foundation (KAW). Two of these researchers are also promoted from Wallenberg Academy Fellows (WAF) to Wallenberg Scholars.
From basic research to medicines
On Saturday December 7 the Erling Persson Hall was filled with anticipation. In three brilliant Nobel Lectures, the laureates describe how research into the systems cells use to deal with hypoxia can lead to improved treatments for anaemia, vascular atrophy and cancer.
Two KI researchers awarded the ERC Consolidator grant
Myriam Aouadi and Camilla Svensson have been awarded the European Research Council’s Consolidator grant 2019 for research on the role of macrophages in liver disease and how autoantibodies contribute to chronic pain, respectively.
New clues to the link between ALS and type 2 diabetes
Patients with ALS (amyotrophic lateral sclerosis) often suffer from type 2 diabetes. This phenomenon has since long remained mechanistically enigmatic. Now, researchers at Karolinska Institutet in Sweden have identified a molecular mechanism linking these two diseases. The study is published in the scientific journal PNAS.
Study debunks notion that C-section would increase risk of obesity in the child
Women who have C-sections are no more likely to have children who develop obesity than women who give birth naturally, according to a study by researchers at Karolinska Institutet in Sweden published in PLOS Medicine. The findings contradict several smaller studies that did find an association between C-sections and offspring obesity but did not consider the numerous maternal and prenatal factors that the researchers did in this study.
A limited selection of recent publications in high impact journals where researchers from KI are main authors.
Genes predict tamoxifen treatment outcome in breast cancer
CYP2D6 Genotype Predicts Tamoxifen Discontinuation and Prognosis in Patients With Breast Cancer, He, W et al, Journal of Clinical Oncology, Dec. 2019.
Individuals with alcohol abuse have epigenetic changes in the brain
Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence, Meng W et al, Molecular Psychiatry, Nov 2019
Contact lens measures eye pressure after transplantation of insulin-secreting cells
Intraocular Pressure Monitoring Following Islet Transplantation to the Anterior Chamber of the Eye, Joohee Kim et al, Nano Letters, Nov 2019.