Next stage ready to enhance Covid-19 diagnoses
Karolinska Institutet has now received the test material that will allow scientists to perform 5,000 analyses a day on patient samples. The lab will be ready next week thanks to the swift cooperation of KI researchers and Knut and Alice Wallenberg Foundation.
Trial drug may block early stages of COVID-19, study in human cells shows
A drug already tested against lung disease could potentially inhibit COVID-19 by reducing the coronavirus load that enters the lungs and other organs. That is according to a study in human cell cultures and organoids by researchers at Karolinska Institutet in Sweden and the University of British Columbia (UBC) in Canada, published in the journal Cell.
Green light for trial study on using blood plasma from recovered COVID-19 patients
In a small clinical trial just granted approval, about 30 COVID-19 patients at Karolinska University Hospital may soon begin to receive blood plasma from people who have recovered from the disease. Sweden’s Ethical Review Authority has approved the trial treatment, and its effectiveness will be evaluated in a study by researchers at Karolinska Institutet and the Karolinska University Hospital.
ERC Advanced Grant for the design of brain cells to combat Parkinson’s disease
The ERC Advanced Grant is one of Europe’s most prestigious programmes for research financing. The grant has now been awarded to Ernest Arenas to tailor dopamine-producing brain cells for patients with Parkinson’s disease.
Air pollution linked to dementia and cardiovascular disease
People continuously exposed to air pollution are at increased risk of dementia, especially if they also suffer from cardiovascular diseases, according to a study at Karolinska Institutet in Sweden published in the journal JAMA Neurology.
Advances in production of retinal cells for treating blindness
Researchers at Karolinska Institutet and St Erik Eye Hospital have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection. The studies are published in the scientific journals Nature Communications and Stem Cell Reports.
Moral distress can affect healthcare personnel during COVID-19 crisis
With rising numbers of COVID-19 cases and a healthcare sector under increasing strain, healthcare personnel can find themselves facing difficult situations and moral challenges. Researchers at Karolinska Institutet and Uppsala University have recently published a paper in the journal Prehospital and Disaster Medicine precising what is known about moral distress, its risk and protection factors and likely implications. They also present suggestions about how the adverse effects can be mitigated.
Milder symptoms and better prognosis in children with COVID-19
Children infected with the new coronavirus generally have less severe symptoms than adults, they rarely need intensive care and very few child deaths have been reported. This according to a systematic review of COVID-19 in children, based on 45 relevant publications and performed by researchers at Karolinska Institutet. The review is published in the scientific journal Acta Paediatrica.
Karolinska Institutet formalises and strengthens its partnership with the City of Stockholm
President of Stockholm City Council, Cecilia Brinck and the President of Karolinska Institutet Ole Petter Ottersen sign today, 23 March, a declaration of intent on a collaboration.
Wallenberg Clinical Scholars for research on rheumatoid arthritis and fat cells' change
Two clinical researchers at KI have been appointed Wallenberg Clinical Scholars 2020. The individual funding of SEK 15 million from Knut and Alice Wallenberg Foundation provides Anca Catrina and Mikael Rydén with the opportunity to deepen their research and disseminate their results in healthcare.
A limited selection of recent publications in high impact journals where researchers from KI are main authors.
Hepatitis D in blood test linked to severe liver disease – but not in all patients
Long-term study of hepatitis D infection at secondary care centers: the impact of viremia on liver-related outcomes, Kamal H et al, Hepathology, March 2020.
Further light on photosynthesis in salt-tolerant microalgae
Structure of a Minimal Photosystem I From the Green Alga Dunaliella Salina, Perez-Boerema A et al, Nature Plants, March 2020
Web tool for meta-analysis give new insights on muscles and exercise at a molecular level
Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity, Pillon NJ et al, Nature Communications, Jan 2020.
KI in the media
The Macchiarini case: timeline
Spotlight on COVID-19
In early 2020, a new coronavirus was identified in China, and it has now caused a worldwide pandemic. The official name for this virus is SARS-CoV-2, and the disease that is caused by the virus is called COVID-19. Here we present news and features about KI's efforts to stop the new coronavirus.
Meet our researchers
What causes depression and why is fat cells so hard to study? These are some of the questions that researchers at KI are interested in. Find interviews and articles prevously published here at the news site or in our popular-science magazine, Medicinsk Vetenskap.