Early food introduction can reduce risk of food allergy in children
Infants who were given a taste of peanut, milk, wheat and egg from the age of three months had a lower risk of developing a food allergy at the age of three years than controls, reports a study by researchers from Karolinska Institutet in Sweden and the University of Oslo in Norway published in The Lancet.
New approach to treatment of deadly kidney cancer
Researchers at Karolinska Institutet have linked resistance to treatment for a deadly form of kidney cancer to low mitochondrial content in the cell. When the researchers increased the mitochondrial content with an inhibitor, the cancer cells responded to the treatment. Their findings, which are published in Nature Metabolism, offer hope for more targeted cancer drugs.
Improved protein function opens way for new drug development concept
Researchers at Karolinska Institutet and SciLifeLab describe in a study published in Science how they have improved the ability of a protein to repair oxidative DNA damage and created a new protein function. Their innovative technique can lead to improved drugs for diseases involving oxidative stress, such as cancer, Alzheimer’s disease and lung diseases, but the researchers believe it has even greater potential.
Successful repatriation of remains to North America
On May 18, Dan Jibréus, who travelled to North America on behalf of the KI to return the remains of two persons, returned to Sweden. He describes the trip as very successful, and the two remains, from the Arikara and Miami peoples respectively, have now been returned to their places of origin.
Three KI researchers among the “Future research leaders“
The Swedish Foundation for Strategic Research, SSF, has appointed the eight generation of "Future research leader", three researchers from Karolinska Institutet. The researchers receive 15 million SEK each during a five year period and will join a leadership training program.
LGBTQI-inclusive work and study environment in focus during pride week
As in previous years, several of Stockholm's academic institutions are joining together with a united theme during Pride week to draw attention to LGBTQI issues. Academic Pride 2022 is organising a seminar on LGBTQI-inclusive work and study environments and joint participation in the Pride Parade. The Pride flag will also be flown at all participating universities throughout the week of this festive week.
Diabetes and cardiovascular disease increase dementia risk
People with at least two of the diseases type 2 diabetes, heart disease or stroke have double the risk of developing dementia. Prevention of diabetes and cardiovascular disease could therefore be a strategy for reducing dementia risk, a study from Karolinska Institutet published in the journal Alzheimer’s & Dementia suggests.
The silent pandemic
Antibiotic resistance is sometimes referred to as the silent pandemic – a contagion that spreads without us really knowing its extent or severity. But research is in progress to find new ways of fighting bacteria. And as with COVID-19, everyone can help to reduce the spread – and save lives.
Patient-initiated brief admission an important complement to psychiatric outpatient care
Patient-initiated brief admission as a complement to outpatient psychiatric care is appreciated by nurses and patients, and can reduce levels of anxiety in people with emotional instability and self-harm, a new thesis from Karolinska Institutet reports.
Red blood cell units from female blood donors do not increase risk of death of transfused patients
A study from Karolinska Institutet sheds new light on the question of whether the sex and previous pregnancy of blood donors affects survival in patients who receive red blood cell transfusions. According to the study, which is published in JAMA Internal Medicine, neither of these factors has such an effect, after accounting for the lower haemoglobin levels in blood from women.
Omicron elicits lower antibody responses in individuals with prior COVID-19 infection
Researchers at Karolinska Institutet and Danderyd Hospital have followed participants who have received three doses of the SARS-CoV-2 vaccine and compared their immune responses after Omicron infection. The results, which are published in The Lancet Infectious Diseases, show that Omicron infection elicits significantly higher antibody responses in individuals without prior COVID-19 infection as compared to previously infected individuals.
Study describes new way of generating insulin-producing cells
Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis. The results are published in Nature Chemical Biology.
Top publications in selection
Low socioeconomic status linked to increased risk of bleeding after aortic valve replacement
Dalén M et al, Journal of the American College of Cardiology, June 2022
”Unexpected finding on the 3D organisation of chromosomes”
Björkegren C et al, Science Advances, June 2022
New study on IRF7 protein deficient patients with COVID-19 and influenza
Campbell T et al, Journal of Experimental Medicine, June 2022
A non-coding RNA regulates gene expression in human mitochondria
Xuefeng Zhu et al, Cell, June 2022
New stem cell-based technology opens for possible future treatment in Parkinson’s
Alekseenko Z et al, Nature Communications, June 2022
Improved method for single-cell RNA-sequencing at scale
Hagemann-Jensen M et al, Nature Biotechnology, May 2022
Blocking calcium pump inhibitor as potential treatment for heart failure
De Genst E et al, Nature Communications, May 2022
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KI in the debate
KI constantly engages in the public debate and comments on current issues concerning our operations. On this page you find published opinion pieces and comments.