Published: 2021-06-17 14:02 | Updated: 2021-06-17 14:06

New thesis on improving stroke risk prediction

röda blodkroppar
Red blood cells, cc: pixabay

Eva Karlöf at the research group Vascular Surgery, the Department of Molecular Medicine and Surgery, will defend her thesis "Improving stroke risk prediction and individualised treatment in carotid atherosclerosis" on June 18, 2021. Main Supervisor is Professor Ulf Hedin.

Eva Karlöf
Eva Karlöf

What's the main focus of your thesis?

To improve stroke prediction and providing a possibility to precision medicine through improved diagnostics of the vulnerable carotid atherosclerotic plaque. 

Which are the most important results?

The most important results are that carotid atherosclerotic plaque biology can be linked to plaque morphology in analysis of CT images. And that plaque biology can be predicted from CT image analysis on a patient-specific level, via machine learning. 

How can this new knowledge contribute to the improvement of people’s health?

We hope to contribute to a higher accuracy regarding which patient should receive which treatment, medical treatment alone (and which in that case) or together with carotid surgery, to prevent stroke more efficiently than today. 

What are your future ambitions?

In order to implement these results into clinical praxis, larger prospective studies are warranted to validate the results, it would be fun to launch and implement such a project.

Dissertation

Friday June 18, 2021, at 9:00, Sune Bergströms Aula J3:07, Karolinska University Hospital Solna

Contact

Eva Karlöf PhD Student