News archive

The Nobel Assembly at Karolinska Institutet has today decided to award the 2019 Nobel Prize in Physiology or Medicine jointly to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza for their discoveries of how cells sense and adapt to oxygen availability.

Atopic dermatitis and psoriasis affect more than 300 million people worldwide and are highly variable in terms of onset, severity, progression over time and response to treatment. BIOMAP will examine the causes and mechanisms of these conditions by identifying the biomarkers responsible for the variation in disease outcome.

On October 7, Dr Jonas F Ludvigsson will make his first appearance as the ”in-house pediatrician” of Swedish television TV4. He will participate regularly in the television show ”Malou efter tio” to discuss health and disease in children.

Researchers at Karolinska Institutet in Sweden have uncovered a chromosome-wide mechanism that keeps the gene expression of sex chromosomes in balance in our cells. The findings shed light on molecular reasons for early miscarriage and could be important for the emerging field of regenerative medicine. The study is published in Nature Structural and Molecular Biology.

Wenjing Tao from the group Upper GI Surgery will defend her thesis "Cancer after bariatric surgery : risk and prognosis" on October 4th, 2019. Main Supervisor is Professor Jesper Lagergren.

The Swedish Magazine Fokus has ranked Henrik Ehrsson, from the Department of Neuroscience, as number 9 out of the 100 most prolific and quoted researchers in Sweden in the area of Medicine & Life Science.

To highlight the World Diabetes Day on November 14 eight internationally recognized scientists are visiting KI and will present their recent findings in the areas of diabetes and cardiovascular disease, gut hormone regulation of metabolism, beta cell pathogenesis and circadian metabolism. Please see the poster and program below.

This is an open symposium, free of charge, however registration is required, follow the link.

Four research projects at Karolinska Institutet receive funding from the Knut and Alice Wallenberg Foundation (KAW) in the project call of 2019. In all, researchers at KI are awarded close to SEK 135 million over a five-year period for studies into MS, mitochondrial disease, and vaccine against rheumatism.

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans. The new variant reduced unintended changes in DNA compared to its wildtype, suggesting it could play a role in gene therapies that require high precision. The study by researchers from Karolinska Institutet’s Ming Wai Lau Centre of Reparative Medicine in Hong Kong is published in the journal PNAS.

A new way of producing nanoparticles that can function as carriers in so-called mRNA vaccines has been developed by researchers at the Hong Kong node of Karolinska Institutet – the Ming Wai Lau Centre for Reparative Medicine – and the MIT, USA. Using the method, which is described in the scientific journal Nature Biotechnology, the researchers have identified a new class of carrier molecules that inhibit tumour growth and prolong survival in mouse models of cancer.

Over 100 representatives from the Swedish life science sector participated in the hearing, whose main purpose was to gather thoughts and input for the SciLifeLab’s road map for the next decade.

At Karolinska Institutet several staff and students are deeply committed to reduce the environmental footprint. One of the many departments at KI taking an active approach to climate issues is the Department of Clinical Neuroscience.

While blood samples can reliably identify people with a low risk of developing severe liver disease, better methods are needed in primary care for identifying people in most need of care. These are some of the conclusions of a large registry-based study by researchers at Karolinska Institutet published in the esteemed journal Gastroenterology.

Researchers at Karolinska Institutet have taken part in the largest study to date on the genetic risk factors for multiple sclerosis (MS). The study, which is published today in the journal Science, corroborates earlier studies and provides new clues as to what causes this neurological disease. The resulting map will prove a vital resource for future researchers and could one day lead to new, more potent drugs.

Hello Claes Frostell, professor and senior physician at the Department of Clinical Sciences at Danderyd Hospital who as of September 1 is KI’s scientific representative for two years.

The partnership between KI and the Mayo Clinic in the US is celebrating its 25th year. Since inception, the collaboration has supported a great many successful research projects and innovations. Sophie Erhardt has recently been appointed as KI’s academic coordinator for the collaborative platform.

To bridge the gap between individual-focused clinical medicine and societal approaches, the course administration for the course ”Hälsa i samhälle och miljö” once again organised a panel debate in collaboration with the Swedish Society of Medicine’s student and junior doctor section. The theme was “Sickness insurance certification by young doctors – how can we improve praxis”.

Two recently graduated students from KI’s Global Master’s Programme in Nutrition Science were among the top 3 teams competing in the Baltic Sea Young Planner’s Contest in Poland. One of them was in the winning team.

Gonçalo Castelo-Branco is awarded the Anniversary Prize for influencing and inspiring international research on brain development, glial cells and multiple sclerosis. The prize includes an award of SEK 5 million and will be presented in conjunction with the Swedish Society for Medical Research’s 100th anniversary celebration.

Title: The comorbidity between attention-deficit/hyperactivity disorder and other neurodevelopmental disorders: aetiology, treatment and outcomes

People – or more specifically just Swedes – are more like chimpanzees than previously known. This is indicated in a genetic mapping of one thousand Swedish individuals, where new DNA sequences that should be included in the reference genome have been identified. The study is published in the scientific journal Molecular Biology and Evolution.

Three grants, of in total 37 MSEK, have been awarded to Karolinska Institutet towards a doctoral programme grant within register-based research and two research environment grants within register-based research. The Swedish Reserach Council awarded in total grants to an amount of 102 MSEK for 2020-2023.

Hi there Kevin Baker, doctoral student at the Department of Public Health Sciences at Karolinska Institutet. Today Friday 20 September you will defend your thesis. Tell us, what is the main focus of your thesis?

Karolinska Institutet’s exit poll, which was sent out for the third time to all 37 undergraduate and second cycle programmes, has now been compiled and presented in a report. The survey is conducted twice a year, for the January and June degree programmes. The response rate was 51% for the Swedish programmes and 71% for the international programmes. The total number of respondents was 1023.

Professor Claes Frostell has been named scientific representative at KI for a period of two years starting September 1, 2019.

The timing of anemia—a common condition in late pregnancy—can make a big difference for the developing fetus, according to research at Karolinska Institutet published in JAMA Psychiatry. The researchers found a link between early anemia and increased risk of autism, ADHD and intellectual disability in the child. Anemia discovered toward the end of pregnancy did not have the same correlation. The findings underscore the importance of early screening for iron status and nutritional counselling.

Drivers, factory workers, and cleaners are three times more likely to develop type 2 diabetes than teachers and physiotherapists. Researchers at Karolinska Institutet in Sweden have studied how the occurrence of diabetes differs between occupations in Sweden. The results are being published in the scientific journal Diabetologia and are also presented at the European diabetes conference in Barcelona in September.

A new method, developed by Banushree Kumar and Simon Elsässer at Karolinska Institutet, produces quantitative maps for modifications of so-called histone proteins that package the DNA molecules in every eukaryotic cell. The study, published in the journal Cell Reports, describes new properties of naïve pluripotent stem cells.

The fall nomination period is now open - all KI employees and students are welcome to nominate representatives to the Faculty Board and Faculty Council between 18 September and 2 October.

Women have an increased risk of high-grade cervical lesions returning after surgery if there have been lesions in the resection margin, especially if high-risk HPV (human papillomavirus) is found in the follow-up test, reports a new longitudinal study from Karolinska Institutet published in The American Journal of Obstetrics and Gynecology. The researchers also found that many other diseases can be independent risk factors in lesion recurrence.

Title: Socioeconomic influences on late-life health and mortality : exploring genetic and environmental interplay 

Title: Risk prediction in prostate cancer diagnostics : current challenges and improvements

As part of the international strategic collaboration between KI-KTH-SU and the University of Tokyo (UTokyo) the three Swedish universities hosted a group of 20 undergraduate students from UTokyo during the first week of September.

Four researchers are awarded Karolinska Institutet’s Grand Silver Medal 2019. They are given the medal for their great contributions to support KI’s activities.

A group of biostatistical scientists at the Department of Medical Epidemiology and Biostatistics (MEB) have been awarded a research environment grant of SEK 13 million from the Swedish Research Council for research into the development and application of statistical methods for register-based research.

After witnessing the positive effects that exercise has had on the wellbeing of breast cancer patients, Yvonne Wengström is certain where she stands: It’s time to introduce physical activity in cancer care across the board.

The Swedish Brain Foundation supports qualified research on the brain and other nervous systems, as well as diseases, injuries and disabilities throughout the nervous system. 98 out of 273 applications were granted funding this year.

One Mind Rising Star Awards was launched in 2005 and is awarded each year to draw attention to and financially support pioneering research on brain injuries and mental illness.

Stanford Medicine X has launched a new self-paced online course through Stanford online with faculty from Stanford University.

Researchers at Karolinska Institutet and Umeå University have examined whether it has any significance if employees and managers agree or not at the introduction of a health-promoting operation.

The Brain & Behavior Research Foundation's NARSAD Young Investigators Grant was awarded for the first time in 1987.

It appears that when our nervous system is developing, only the most viable neurons survive, while immature neurons are weeded out and die. This is shown in a ground-breaking discovery by researchers at Karolinska Institutet in Sweden. The results indicate that the long-standing neurotrophic theory, which states that chance determines which cells will form the nervous system, needs to be revised.

Professor Jesper Lagergren from the research group Upper GI Surgery, the Department of Molecular Medicine and Surgery, receives research grants of SEK 13 million from the Swedish Research Council.

Researchers at Karolinska Institutet have studied the effects of exercise in a mouse model of premature ageing. The study with fellow researchers from Harvard Medical School, was recently published in the journal Aging Cell.

Many people struggle to keep their weight in check as they get older. Now new research at Karolinska Institutet has uncovered why that is: Lipid turnover in the fat tissue decreases during ageing and makes it easier to gain weight, even if we don’t eat more or exercise less than before. The study is published in the journal Nature Medicine.

Karolinska Institutet’s Vice President Karin Dahlman-Wright has today requested to be relieved from her assignment as vice president with immediate effect. Consequently, KI’s University Board (Konsistoriet) agreed to relieve her from the assignment at an extra meeting today.

A complaint was filed in July 2018 against the vice president of Karolinska Institutet (KI), Karin Dahlman-Wright, for suspicion of research misconduct. In order to avoid conflict of interest, in August 2018, KI reached an agreement with the University of Gothenburg to manage the investigation.

On August 22, the Government appointed Carin Götblad as a new member of the Board of Karolinska Institutet. Carin Götblad replaces Liselotte Højgaard who has asked to be dismissed.

Two researchers at Karolinska Institutet, Per-Olof Berggren and Birgitta Henriques-Normark, receive a total of SEK 68 million in grants from the Swedish Foundation for Strategic Research, SSF. The Med-X research program is an interdisciplinary initiative in medicine and technical science. The purpose is to provide new solutions for clinical needs.

Researchers at Karolinska Institutet have, together with colleagues from Aalto University in Finland, developed a new method for creating images of molecules in cells or tissue samples. The method is based on the use of DNA snippets and is called DNA microscopy. The approach is currently described in the scientific journal PNAS.