News archive

It is possible to leave most of the lymph nodes in the armpit, even if one or two of them have metastases larger than two millimetres. This is shown in a trial enrolling women from five countries, led by researchers at Karolinska Institutet and published in the New England Journal of Medicine. The results open up for gentler surgery for patients with breast cancer.

We congratulate Paolo Parini at the Department of Medicine, Huddinge (MedH) who has received a project grant from Vetenskapsrådet.

To see the changes you advocate for, the ability to make a difference in students’ lives and meeting new people. These are the things that KI student Manojj Dhinakaran likes most about being a student representative.

Global health challenges are the focal point of two collaborative projects coordinated by KI: WISDOM and Changemaker. Under its pillar II "Global Challenges and European Industrial Competitiveness" programme, Horizon Europe has awarded the projects a total grant of EUR 14 million, of which KI controls the equivalent of just over EUR 3 million.

In a new study published in Molecular Oncology, researchers have discovered a novel mechanism to enhance the body’s immune response to tumors. The study is a result of collaboration between Sprint Bioscience, Karolinska institutet, the Luxembourg Institute of Health and Deciphera Pharmaceuticals, and was included as a manuscript in Yasmin Yu’s PhD thesis at the Department of Oncology-Pathology in 2021.

Radboud University in collaboration with NeurotechEU invites KI students and PhDs to a summer school in “Neurotechnologies in Cellular and Systems Neuroscience”

On Thursday, 28 March, the Sune Bergström auditorium at Karolinska University Hospital was filled with Ukrainian paramedics, when the hospital, together with the Centre for Health Crises at Karolinska Institutet, arranged a visit dedicated to the exchange of experiences, discussions, and guided tours.

In January 2024, a delegation from the Institute for Quantitative Biosciences at the University of Tokyo had the privilege of visiting Karolinska Institutet. During this short but invaluable experience, they engaged with the Department of Cell and Molecular Biology's administrative staff, gaining insights into the administrative procedures and organizational structure.

With the progress in treatment for most cancer types, there is a growing interest to understand the overall impact of a cancer diagnosis throughout the remaining lifespan. In addition to conventional survival probabilities, estimating Life Expectancy following cancer diagnosis and Loss in Life Expectancy for cancer patients in comparison to if they did not have cancer provides valuable insights into the societal burden of cancer.

As part of the integration of BioNut into MedH the administration of MedH will move to floor 8 in Neo where they will join the administration of BioNut. The move will take place on 9 April.

The human mouth is a bustling ecosystem teeming with microscopic life. While we often associate oral health with brushing, flossing, and regular dental check-ups, there’s more to the story. A recent review article published in Periodontology 2000 by researchers at Karolinska Institutet, collaborating with researchers in South Korea, Sri Lanka and Australia, delves into the intricate world of oral microbes and their potential impact on oral pathologies, including cancer development.

Follow-up and treatment of children with cancer is significantly improved when inherited genetic causes are also investigated, according to a new Swedish study. The results of the research study involving some 50 researchers and clinicians from across Sweden have been published in The Lancet Regional Health – Europe.

Karolinska Institutet awards grants from a large number of foundations and from donations. The foundations and donations award research and travel grants.

The guidelines for weight gain during pregnancy in obese women have long been questioned. New research from Karolinska Institutet supports the idea of lowering or removing the current recommendation of a weight gain of at least 5 kg. The results are published in The Lancet.

Type 1 diabetes, a chronic condition affecting millions of young individuals globally, is not exclusive to childhood. As much as half of all cases are diagnosed during adulthood, and there is a need to understand factors contributing to the development of type 1 diabetes in adults. A new study at Karolinska Institutet now provides new insights into the development of the disease in adults. The results are presented in Lancet Diabetes & Endocrinology.

Women with premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) have a higher risk of perinatal depression. Conversely, women with perinatal depression have a higher risk of developing premenstrual disorders. This is shown in a study from Karolinska Institutet published in the journal PLOS Medicine.

Researchers at Karolinska Institutet, in collaboration with JLP Health and others, have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are published in Nature Microbiology and are an important step in the development of drugs against the deadly disease.

Karolinska Institutet and Makerere University in Uganda have been working together for over 20 years. In 2021 they established a Centre based on their strong partnership to bring people together, recognize their health challenges and mobilize actions towards well-being. Today the Centre provides tools, resources and training programs for researchers, students, professionals and policy makers globally.

This is a summary of the information meeting that Maria Eriksdotter, head of the Integration project and the former Dean of KI South, held together with Petter Höglund, the departmental head of MedH, and Agneta Wallin Levinovitz, project manager, on 26 March on Zoom addressing all staff at BioNut and MedH.

Ki researcher Daniel Berglind received 6 million SEK from Formas for a project to reconstruct schoolyards with greenery for a better environment and more physically active children in urban areas.

Tigist Dires Gebreyesus is an Ethiopian public health specialist with a master’s in public health from University of Gondar, Ethiopia. She has been working within the Ethiopian Food and Drug Authority, the former Ethiopian Food, Medicine and Healthcare Administration and Control Authority. In December 2023, Dr Gebreyesus defended her doctoral thesis that was part of the PROFORMA project at Karolinska Institutet, Department of Global Public Health.

The Ming Wai Lau Centre for Reparative Medicine (MWLC) announces the 2024 MWLC Seed Grants for KI researchers to fund and promote new research collaborations within stem cell differentiation, reprogramming and biomanufacturing toward translational application. Five proposals will be funded with a budget of 1 000 000 Swedish kronor per year for a maximum period of three years.

The 2024 Svedberg Prize is awarded to Björn Reinius, Department of Medical Biochemistry and Biophysics at Karolinska Institutet, for his discoveries regarding the gene regulation mechanisms of the X chromosome and his substantial impact on COVID-19 clinical diagnostics.

Tips from KI Grants Office about current calls

Finance, telephony and licence managers can now change the project number of IT services charged through the Companion system.

Just like most European capitals, Stockholm previously had a museum of medical history, located in the old Eugeniahemmet next to KS and KI. However, the museum was closed in 2015. Since then, the museum’s large collection of items has been stored and is now managed by the Friends of the Museum of Medical History.

The Wallenberg Scholars program aims to provide leading researchers in Sweden with grants for free research. Following a comprehensive international peer review, the Foundation has chosen to fund 118 researchers for five years, providing up to SEK 18 million each for researchers in theoretical subjects and up to SEK 20 million each for researchers in experimental subjects. Of the 29 medical researchers awarded this year's Scholar grants, 19 are active at Karolinska Institutet.

Catherine J. Wu, of the Dana-Farber Cancer Institute in Boston, USA, is a pioneer in research that may result in the development of personalised vaccines to treat cancer. She is now awarded the Sjöberg Prize, worth one million US dollars, for her work. Catherine J. Wu will give a lecture in Aula Medica at KI on April 12 in connection with the Karolinska CCC Day.

Minister for Health Care Acko Ankarberg Johansson and Minister for Older People and Social Security Anna Tenje recently visited BioClinicum at Karolinska Institutet to learn more about the current status of Alzheimer’s research. "We’re getting closer to being able to devise an effective treatment," says Bengt Winblad, professor at the Department of Neurobiology, Care Sciences and Society, who hosted the visit.

In a new study, Patricia Eustachio Colombo and her colleagues have developed suggestions for healthy and climate-friendly dietary patterns. Now it's just a matter of getting us to adopt them.

Caroline Ingre receives a Royal grant

Ullakarin Nyberg is a researcher at the Center for Psychiatry Research at Karolinska Institutet. She also works clinically as a psychiatrist, part of the time at a unit for breast cancer patients. At the end of 2018, she contracted the disease herself.

Anna Sylvan was diagnosed with breast cancer in the autumn of 2021. Three tumours were treated with surgery, chemotherapy, radiation, and anti-hormones. In this interview she talks about her experience.

Can breast cancer patients who exercise get better results from their chemotherapy? And if so, should they receive treatment that includes exercise? This will be investigated in an international study led by researcher Jana de Boniface.

It is difficult to draw firm conclusions about how to eat and drink to avoid breast cancer. Dietary studies often rely on self-reporting, while dietary habits change over the course of a lifetime - both of which are complicated for researchers. But one link is well documented: even moderate alcohol consumption increases the risk of developing the disease, says Professor Alicja Wolk.

There is a lot going on in breast cancer research. A new AI tool is trying to fine-tune the screening program, another is helping pathologists make diagnoses, and new drugs are being tested and approved. This could save more lives. But there is still no answer to the trickiest question of all: Why does breast cancer occur?

KI will be expanding the Master's Programme in Global Health from a one-year programme to a two-year master's programme. KI has been offering the master's program in global health since 2012. In the fall semester of 2025, the first batch of students will begin the first round of the two-year master's program.

The 13 March, Karolinska Institutet hosted several prominent researchers from The Lancet Global Health Commission on Medical Oxygen Security at the Widerström building, with a focus on discussing how to secure the availability of medical oxygen in the world.

The Swedish government has appointed an advisory group in the field of life science. The group includes experts from academia, industry and healthcare. KI's President Annika Östman Wernerson is one of the members of the group, whose purpose, among other things, is to contribute to the implementation of the national strategy for life science.

Tips from KI Grants Office about current calls

The storage for printer papers and toners has moved on the 7th floor.

Professor Paul Dickman at the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet is awarded the prize Statistical Promotor of the year from the Swedish Statistical Society (Svenska statistikfrämjandet).

The internal team investigating the freezer malfunction in Neo is entering the final phase of compiling its incident report. The report has taken time in order for it to be as complete as possible, as all aspects of the malfunction, from organisational causes to the technical failure, need to be included. The report must be ready by 27 March as IVO (amongst others) has issued a request to receive it. [Following the publication of this text, the finalisation of the report has been postponed.]

Using advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop. The new results are presented in the journal Cell by researchers from Karolinska Institutet and Stockholm University.

Individual patients with autoimmune diseases can receive tailored medication by computationally treating their so-called digital twins with thousands of medications. This is according to an international study published in Genome Medicine by researchers from Karolinska Institutet.

On April 1, 2024, KI will switch to digital degrees. This means that all degree certificate issued after April 1 will be digital and will no longer be printed on paper and sent by mail.

In a recently published review in the journal Biomarker Research, Joanna Zawacka, Docent at the department of Oncology-Pathology discusses our current understanding of p53 biology in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

Researchers from Karolinska Institutet, AstraZeneca, Würzburg University, Science for Life Laboratories and Uppsala University have found that oxidative stress in heart failure varies depending on sex, with female mouse hearts having stronger natural defenses against oxidative damage. The study could enable new approaches for precision medicine and may explain why previous attempts to use antioxidants for treating heart failure have not been so successful.

A mobile app that uses artificial intelligence, AI, to analyse images of suspected skin lesions can diagnose melanoma with very high precision. This is shown in a study led from Linköping University where the app has been tested in primary care. The results have been published in the British Journal of Dermatology.

Interesting Swedish data, where the definition of triple negative breast cancer (TNBC) differs from that used internationally, brings additional insights to on ongoing discussion in the scientific community. The study was presented at the 2023 European Society for Medical Oncology (ESMO) meeting and is now published in Lancet Regional Health- Europe.