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Nobel Week is soon to come, bringing together all the Nobel Laureates in Stockholm. One of them, Tomas Lindahl, one of this year's three Nobel Laureates in Chemistry, made many of his pioneering discoveries at Karolinska Institutet.

A population of ‘stop cells’ in the brainstem is essential for the ability of mice to stop their locomotion, according to a new study by scientists at Karolinska Institutet. In an article published in the journal Cell, they report a brainstem pathway specifically dedicated to enforce locomotor arrest: its selective activation stops locomotion, while its silencing favors it. The study thus identifies a novel descending modality essential for gating the episodic nature of locomotor behavior.

Sonia Lain has been appointed Professor.

A mechanical valve prosthesis has a better survival record than a biological valve prosthesis, according to a large registry study from Karolinska Institutet. The finding, which is published in the European Heart Journal, can be highly significant, since the use of biological valve prostheses has increased in all age groups in recent years.