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Researchers at Karolinska Institutet, Germany’s Technical University of Munich (TUM) and AstraZeneca, among others, have identified a unique therapeutic approach with the potential to restore heart function following a heart attack. The new findings rely on so-called human ventricular progenitor (HVP) cells to promote novel heart tissue and reduce scarring after injury. This pre-clinical study is published in the journal Nature Cell Biology.
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Researchers at Karolinska Institutet have studied long-term morbidity and mortality in individuals who have had different models of biological heart valves implanted. The results, which show that there are considerable differences in performance depending on model group, are published in the journal JAMA Network Open.
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Sweden is one of the few countries that have removed the dental health recommendation to give prophylactic antibiotics to people at a higher risk of infection of the heart valves, so-called infective endocarditis. Since the recommendation was removed in 2012, there has been no increase in this disease, a registry study from Karolinska Institutet published in the journal Clinical Infectious Diseases shows.
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The risk of developing cardiovascular disease is strongly associated with the “bad” LDL cholesterol. A large study by scientists at Karolinska Institutet now shows that two proteins that transport cholesterol particles in the blood provide early and reliable risk information. The researchers advocate introducing new guidelines for detecting cardiac risk and say the results, published in PLOS Medicine, may pave the way for early treatment, which could help lower morbidity and fatality rates.
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Socioeconomic factors affect the risk of cardiovascular disease and the chances of recovery. New research from Karolinska Institutet interrogates the significance of socioeconomic factors for sudden out-of-hospital cardiac arrest. The study, which is published in Circulation, shows that education and income impact survival rates in both men and women.
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Kristina Haugaa is the new Professor of Cardiology at the Department of Medicine in Huddinge, since October 11. "I'm eager and thrilled to conduct cardiology research at Karolinska Institutet".
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Audience: Medarbetare
Medicin, Huddinge
Researchers at Karolinska Institutet have examined long-term outcomes in patients who received pacemaker implantations after transcatheter aortic valve replacement through their groin. The result showed no significant difference in mortality for the patients with pacemakers compared to those without. The study is published in the journal JACC: Cardiovascular Interventions.
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Screening for atrial fibrillation in 75- and 76-year-olds could reduce the risk of stroke, severe bleeding and death, according to a study at Karolinska Institutet in Sweden that has been published in the journal The Lancet.
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Researchers at Karolinska Institutet in Sweden can now report the results of a unique pilot project where drones were used to deliver defibrillators to real-life alerts of suspected cardiac arrest. The drones were dispatched in more than a fifth of the emergencies and arrived on target and ahead of the ambulance in most cases. The results are published in the European Heart Journal and presented today at the European Society of Cardiology congress.
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Researchers at Karolinska Institutet have identified eight primary factors that increase the risk of a common bleeding complication after heart attack. Some of these factors are already known, but using machine learning techniques, the researchers have found additional predictors, such as smoking, blood pressure and blood glucose.
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In almost ten per cent of myocardial infarctions, no obvious cause in the coronary artery can be found. Some of the patients are diagnosed with broken-heart syndrome, while others are left without a diagnosis. A new study from Karolinska Institutet in Sweden suggests that early magnetic resonance (MR) imaging of the heart can greatly increase the rate of diagnosis. The study has been published in the journal JACC Cardiovascular Imaging.
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Men with stable coronary artery disease who are on Viagra due to impotence seem to live longer and have a lower risk of experiencing a new heart attack, a study from Karolinska Institutet in Sweden published in the Journal of the American College of Cardiology reports.
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Concerns have been raised that the use of a common group of medications called RAS inhibitors could facilitate SARS-CoV-2 infection, impact COVID-19 disease severity and worsen prognosis. However, in a new nationwide registry-based study from Karolinska Institutet, including almost 1.4 million patients, use of RAS inhibitors was not associated with increased risk of hospitalisation or death from COVID-19. The study has been published in the European Journal of Heart Failure.
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The financial burden on health systems would drastically increase if new European expert guidelines for cholesterol-lowering treatment were implemented, according to a new simulation study by researchers at Karolinska Institutet in Sweden, published in the European Heart Journal. The findings highlight an urgent need for cost-effectiveness analysis given the current cost of the proposed treatment for very high-risk patients, the researchers say.
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High levels of traffic exhaust at one’s residence increases the risk of stroke even in low-pollution environments, according to a study by researchers at Karolinska Institutet and other universities in Sweden. The study, published in the journal Environmental Health Perspectives, suggests that it is mainly black carbon from traffic exhaust that increases the risk for stroke, and not particulate matter from other sources.
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Patients with a near relative that has experienced a myocardial infarction, has an over 60 % increased risk of also being afflicted when attending the emergency with chest pain. Researchers from Karolinska Institutet have observed this association by combining data in a completely new way. The results are published in European Heart Journal: Acute Cardiovascular Care.
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08-06-2022