Andri Papakonstantinou and Sean Rudd appointed docents in cancer and oncology

Andri Papakonstantinou and Sean Rudd have been appointed docents in cancer and oncology at Karolinska Institutet. Both are based at the Department of Oncology-Pathology.
Andri Papakonstantinou, docent in cancer and oncology, is part of the Translational Breast Cancer Research group, led by Theodoros Foukakis.
Her research focuses on breast cancer, with a particular emphasis on how modern treatments can affect the heart, as well as other toxicities, and how care can be tailored to individual patients. This includes studying the risk of cardiotoxicity and developing methods to identify, at an early stage, patients who require closer monitoring, with the aim of making treatment both more effective and safer.
Sean Rudd, docent in experimental cancer and oncology, leads the Nucleotide Metabolism and Molecular Pharmacology research group, where his research focuses on how commonly used cancer drugs function at the molecular level and why patients respond differently to treatment.
This includes examining how chemotherapy affects DNA and the cell’s nucleotide building blocks, as well as how cancer cells can develop resistance, with the aim of improving the effectiveness of existing treatments and tailoring them more closely to individual patients.
Together, their research contributes to more precise and less harmful cancer treatment, taking both efficacy and side effects into account.
