News archive

On this page you can search for older news. Choose a topic, type of news or enter your own keyword to filter out news.

View expanded
View compact
By measuring immune cells in the cerebrospinal fluid when diagnosing ALS, it is possible to predict how fast the disease may progress according to a study from Karolinska Institutet published in Nature Communications.
News
Infections treated with specialty hospital care in early- and mid-life are associated with an increased subsequent risk of Alzheimer’s and Parkinson’s diseases, but not amyotrophic lateral sclerosis (ALS), according to a study by researchers from Karolinska Institutet, published in PLOS Medicine.
News
Using a novel 3D imaging technology, researchers at Karolinska Institutet, among others, have been able to comprehensively characterize a part of the brain that shows perhaps the earliest accumulation of tau protein, an important biomarker for the development of Alzheimer's disease. The results, published in the journal Acta Neuropathologica, may make it possible in the future to have a more precise neuropathological diagnosis of the Alzheimer’s disease spectrum at a very early stage.
News
The repurposing of FDA-approved drugs for alternative diseases is a faster way of bringing new treatments into the clinic. Researchers at Karolinska Institutet have repurposed a cancer drug for treatment of neuroinflammatory diseases such as multiple sclerosis. A novel drug carrier was also developed to facilitate drug delivery to target myeloid cells. These pre-clinical findings are described in a paper in the journal EMBO Reports.
News
StratNeuro is partnering with the “Human Brains” initiative by Fondazione Prada, that will include in 2022 a series of events (local workshops, global roundtable discussions, conference and an exhibition at Prada Museum in Milano). Karolinska Institutet is one of 13 leading universities and institutions from across the world to participate in this initiative.
News
Audience: Medarbetare
Hi Linn Öijerstedt, PhD student at the Division of Neurogeriatrics, NVS. On January 20 you will defend your thesis ”Biomarkers in frontotemporal dementia : findings from the GENFI study”, what's the main focus of the thesis?
News
Researchers at Karolinska Institutet in Sweden have identified a protein that improves muscular metabolism, motor coordination and exercise performance in mice. The findings, published in Cell Metabolism, could be of therapeutic value for patients with muscle and neurological diseases, such as ALS.
News
Professor Per Svenningsson at Karolinska Institutet receives funding for a five-year research project of 38 million SEK from Nordstjernan Holding AB and the Axel Johnson Group. The investment goes to fundamental research on the onset of Parkinson's disease and to clinical studies to improve treatment and slow down the course of the disease.
News
Joana Pereira officially starts as research group leader today, June 1, although she has been managing her own group for a while now.
News
The causes of the serious muscle disease ALS still remain unknown. Now, researchers at Karolinska Institutet and KTH Royal Institute of Technology, among others, have examined a type of cell in the brain blood vessels that could explain the unpredictable disease origins and dynamics. The results indicate a hitherto unknown connection between the nervous and vascular systems. The study, published in Nature Medicine, has potential implications for earlier diagnoses and future treatments.
News
Disorders of the cells’ energy supply can cause a number of serious diseases, but also seem to be connected to ageing. More research is needed on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet shows how an important molecule inside the mitochondria affects their function in mice and fruit flies. The study, which is published in Science Advances, adds valuable knowledge on formerly relatively unexplored protein modifications.
News
People who consume high levels of vitamin C and E in their diet may have a lower risk of Parkinson’s disease than people who get only small amounts of these nutrients, according to a new study from University of Milano-Bicocca, Italy, and Karolinska Institutet. The study was published in Neurology.
News
Gilberto Fisone has been awarded a three-year research grant from the Swedish Research Council within the program Novel Imaging and Brain Stimulation Methods and Technologies (JPND) for a project entitled "Phage-based targeted neural stimulation in neurodegenerative diseases".
News
People with multiple sclerosis (MS) gradually develop increasing functional impairment. Researchers at Karolinska Institutet have now found a possible explanation for the progressive course of the disease in mice and how it can be reversed. The study, which is published in Science Immunology, can prove valuable to future treatments.
News
Researchers at Karolinska Institutet have imaged tau protein in the brains of living patients with Alzheimer’s disease. The amount and spread of tau proved a predictor of future memory loss. Brain imaging for measuring tau can be useful both for improving diagnosis and for developing more effective treatments, say the researchers. The study is published in the journal Molecular Psychiatry.
News
The focus of Johanna Sieurin's thesis was to investigate the relationship of personality and stress with subsequent risk of Parkinson’s disease (PD).
News
Many nerve cells in the brain region hypothalamus have unexpected origins and go through complex development programs, where millions of neurons assemble into a precisely knit network by birth. That is according to a study by researchers at Karolinska Institutet in Sweden and the Medical University of Vienna published in the journal Nature. The findings may further our understanding of hormonal diseases and their origins, according to the researchers.
News
Gustav Mårtensson, PhD-student at the Division of Clinical Geriatrics. On May 15, 2020 you will defend your thesis "Quantifying neurodegeneration from medical images with machine learning and graph theory", what's the main focus of the thesis?
News
Researchers at Karolinska Institutet and from the Netherlands have developed a simple tool that shows the survival probability of a person with dementia disease over three years. This, they hope, will facilitate dialogue with the most seriously affected and help doctors and others plan the necessary care. The study is published today in the scientific journal Neurology.
News
Patients with ALS (amyotrophic lateral sclerosis) often suffer from type 2 diabetes. This phenomenon has since long remained mechanistically enigmatic. Now, researchers at Karolinska Institutet in Sweden have identified a molecular mechanism linking these two diseases. The study is published in the scientific journal PNAS.
News
On Friday December 18, Elisa Longinetti will defend her thesis "Amyotrophic lateral sclerosis and multiple sclerosis associated neuroinflammation: nationwide epidemiological studies on etiology, comorbidities, and treatment"
News
Researchers at Karolinska Institutet have developed a new method to separate between two different types of a common herpes virus (HHV-6) that has been linked to multiple sclerosis. By analyzing antibodies in the blood against the most divergent proteins of herpesvirus 6A and 6B, the researchers were able to show that MS-patients carry the herpesvirus 6A to a greater extent than healthy individuals. The findings, published in Frontiers in Immunology, point to a role for HHV-6A in MS development.
News
Those with a family history of schizophrenia and men with lower IQ are more likely to struggle with treatment resistant schizophrenia than others with the mental disorder, according to a study by researchers at Karolinska Institutet in Sweden published in the journal Molecular Psychiatry. The researchers say the findings could be important in efforts to design novel drug treatments that improve cognition.
News
People with multiple sclerosis (MS) who also have depression are more likely to suffer debilitating symptoms early than people with MS who are not depressed, according to a study at Karolinska Institutet in Sweden that is published in the journal Neurology. The findings highlight the need for early recognition and treatment of depressive symptoms in patients with MS.
News
People with multiple sclerosis who can walk at a relatively normal speed and effectively process information are more likely to continue to participate in social activities, according to a new study by researchers at Karolinska Institutet in Sweden published in the Multiple Sclerosis Journal. The findings highlight the importance of integrating motor and cognitive rehabilitation in the care of patients with MS.
News
Four research projects at Karolinska Institutet receive funding from the Knut and Alice Wallenberg Foundation (KAW) in the project call of 2019. In all, researchers at KI are awarded close to SEK 135 million over a five-year period for studies into MS, mitochondrial disease, and vaccine against rheumatism.
News
26 September, 2019
Major genome map of MS
Researchers at Karolinska Institutet have taken part in the largest study to date on the genetic risk factors for multiple sclerosis (MS). The study, which is published today in the journal Science, corroborates earlier studies and provides new clues as to what causes this neurological disease. The resulting map will prove a vital resource for future researchers and could one day lead to new, more potent drugs.
News
It appears that when our nervous system is developing, only the most viable neurons survive, while immature neurons are weeded out and die. This is shown in a ground-breaking discovery by researchers at Karolinska Institutet in Sweden. The results indicate that the long-standing neurotrophic theory, which states that chance determines which cells will form the nervous system, needs to be revised.
News
Three researchers at Karolinska Institutet have been appointed Wallenberg Scholar in 2019: Ernest Arenas, Sten Linnarsson, and Randal S. Johnson. The researchers – among the foremost in their field in Sweden – receive SEK 18 million each from the Wallenberg Foundations in the form of a five-year grant for free research.
News
Subpopulations of oligodendrocytes, myelin-producing cells in the brain that are targeted by the immune system in multiple sclerosis (MS), are altered in MS and might therefore have additional roles in the disease than previously described. The results are published in the journal Nature, in a study led by researchers at Karolinska Institutet in Sweden and University of Edinburgh in the UK.
News
A new study shows that there is a very limited regeneration of cells in the brain of patients diagnosed with multiple sclerosis (MS). These findings underline the importance of treating MS at an early stage of the disease progression, when the affected cells can repair the damage as they are not replaced by new ones. The results are published in the journal Nature by researchers from Karolinska Institutet and Uppsala University.
News
Although Parkinson’s disease is often associated with motor symptoms such as stiffness, poor balance and trembling, the first symptoms are often sensory and include a reduced sense of touch and smell. In a study on mice, researchers at Karolinska Institutet have now been able to identify neural circuits and mechanisms behind this loss of sensory perception. The study, which is published in the scientific journal Neuron, may open avenues to methods of earlier diagnosis.
News
Researchers at Karolinska Institutet have made significant progress in the search for new treatments for Parkinson’s disease. By manipulating the gene expression of non-neuronal cells in the brain, they were able to produce new dopamine neurons. The study, performed on mice and human cells, is published in the prestigious scientific journal Nature Biotechnology.
News
The growth factor IGF-2 can prevent the death of human nerve cells in the incurable disease ALS, according to a study by researchers at Sweden´s Karolinska Institutet and the University of Milan in Italy. The study, which is published in the journal Scientific Reports, demonstrates that degeneration-resistant oculomotor neurons can be used as a tool to identify factors able to prevent the degeneration of vulnerable neurons caused by this deadly disease.
News
KW
KI webbförvaltning
08-06-2022