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Patient-initiated brief admission as a complement to outpatient psychiatric care is appreciated by nurses and patients, and can reduce levels of anxiety in people with emotional instability and self-harm, a new thesis from Karolinska Institutet reports.
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Six predictors could help determine the amount of lithium needed to treat patients with bipolar disorder, according to a large study led by researchers at Karolinska Institutet in Sweden. The study, published in the journal The Lancet Psychiatry, also pinpoints genetic markers that seem to influence how quickly the body eliminates lithium from its system.
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Children with migration backgrounds in Sweden are less likely than other children to receive recommended treatment for psychiatric diagnoses such as ADHD and depression, a paper from Karolinska Institutet published in the journal Epidemiology and Psychiatric Sciences reports.
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Scientists have analysed DNA from more than 300,000 people with and without the psychiatric disorder in the largest genetic study of schizophrenia to date and have identified a great number of specific genes that could play important roles in the psychiatric disorder. A companion paper published in parallel strengthens these findings by pointing to a similar genetic and biological basis for this disorder. Both studies are published today in the leading international journal Nature.
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Sexual and gender-based harassment in the workplace can contribute to the development of mental ill-health requiring treatment with antidepressants and anti-anxiety medication, a study from Karolinska Institutet in Sweden published in the journal Occupational and Environmental Medicine reports.
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Use of assisted reproductive techniques (ART) does not lead to poorer mental health in children across adolescence and young adulthood, according to a large observational study led by researchers at Karolinska Institutet. The study, published in JAMA Psychiatry, found a slightly higher risk of obsessive-compulsive disorder for those born after ART but this was explained by parental background factors.
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It remains a central challenge in psychiatry to reliably judge whether a patient will respond to treatment. In a new study published in the journal Biological Psychiatry, researchers from Karolinska Institutet in Sweden and the Max Planck Institute for Human Development in Germany show that moment-to-moment fluctuations in brain activity can reliably predict whether patients with social anxiety disorder will be receptive to cognitive behavioural therapy (CBT).
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Patients with bipolar disorder who experience manic episodes are more likely to show abnormal brain changes over time, according to one of the largest longitudinal brain imaging studies in its field to date. The study, led by researchers at Karolinska Institutet and University of Gothenburg in Sweden, also confirms links between bipolar disorder and accelerated brain ventricle enlargement. The findings are published online in the journal Biological Psychiatry.
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The discovery that the anaesthetic ketamine can help people with severe depression has raised hopes of finding new treatment options for the disease. Researchers at Karolinska Institutet have now identified novel mechanistic insights of how the drug exerts its antidepressant effect. The findings have been published in the journal Molecular Psychiatry.
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Depressed children and teenagers have an increased risk of suffering from premature death and a wide range of illnesses later in life. That is according to a large observational study by researchers at Karolinska Institutet in Sweden. The findings highlight the need to look for other potential diseases following childhood or adolescent depression. Other psychiatric conditions, such as anxiety and substance misuse, can explain part of the association. The study is published in JAMA Psychiatry.
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Migrants from Africa and the Middle East and their children are more likely to be placed under compulsory care than the Swedish-born population when admitted to hospital for psychosis for the first time. That is according to a large, nationwide study by researchers at Karolinska Institutet in Sweden and University College London in the U.K., published in the journal Psychological Medicine.
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Researchers at Karolinska Institutet show that different measures of psychopathology can be combined into a single factor, “p”, which predicts the patient’s prognosis and need of extra support. The general factor of psychopathology reflects the overall risk of adverse psychiatric outcomes with an accuracy equal to that currently used for intelligence, they report in a paper published in World Psychiatry.
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Pregnant women with eating disorders should undergo extended pregnancy screenings considering their increased risk of complications. That is the conclusion from a study by researchers at Karolinska Institutet in Sweden published in the journal JAMA Psychiatry. The researchers were, for example, able to show that children to mothers with eating disorders had an increased risk of premature birth and being born with a small head circumference.
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People with multiple sclerosis (MS) who also have depression are more likely to suffer debilitating symptoms early than people with MS who are not depressed, according to a study at Karolinska Institutet in Sweden that is published in the journal Neurology. The findings highlight the need for early recognition and treatment of depressive symptoms in patients with MS.
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Refugees and other migrants who move to Sweden are initially less likely to be diagnosed with alcohol or drug addiction than the native population but over time their rates of substance abuse begin to mirror that of the Swedish born population. That is according to a new study by researchers at UCL in the U.K. and Karolinska Institutet in Sweden published in the journal PLOS Medicine.
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Title: The comorbidity between attention-deficit/hyperactivity disorder and other neurodevelopmental disorders: aetiology, treatment and outcomes
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Children with Inflammatory Bowel Disease (IBD) run a greater risk of psychiatric disorders, according to a new study from Karolinska Institutet in Sweden published in JAMA Pediatrics. The researchers claim that more psychological support and longer follow-up is needed for the children affected and their parents.
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Psychiatric comorbidity may play an important role in the increased risk of premature death in people with ADHD (attention-deficit/hyperactivity disorder), according to a new extensive registry study conducted at Karolinska Institutet and Örebro University in Sweden. The results, which are published in JAMA Psychiatry, suggest that improved awareness and care of psychiatric comorbidities such as substance use disorders may help reduce serious outcomes associated with ADHD.
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An initial gene analysis may yield better outcomes when patients are treated with the antipsychotic drugs risperidone and aripiprazole. A novel study shows how the activity of a specific enzyme, which metabolises the two drugs, affects the individual dose that should be given for optimal treatment. The study is published in The Lancet Psychiatry and has been conducted by researchers at Karolinska Institutet, in collaboration with the Diakonhjemmet Hospital in Oslo, Norway.
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Hi there Linda P. Sturesson, PhD student at the Department of Learning, Informatics, Management and Ethics. Your new book "Diskvalificering av det positiva" (Disqualification of the positive) was released on April 11th.
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Scientists at Karolinska Institutet in Sweden and University of North Carolina, USA, have identified the cell types underlying schizophrenia in a new study published in Nature Genetics. The findings offer a roadmap for the development of new therapies to target the condition.
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Researchers at Karolinska Institutet collaborating in the large-scale Karolinska Schizophrenia Project are taking an integrative approach to unravel the disease mechanisms of schizophrenia. In the very first results now presented in the prestigious scientific journal Molecular Psychiatry, the researchers show that patients with schizophrenia have lower levels of the vital neurotransmitter GABA as well as changes in the brain’s immune cells.
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A new study, in which researchers at Karolinska Institutet participated, has found that in mice adjusting levels of a compound called kynurenic acid can have significant effects on schizophrenia-like behavior. The study is published in the journal Biological Psychiatry.
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Imagined ugliness, or body dysmorphic disorder (BDD) as it is known, can be treated with internet-based CBT, according to a recent randomised study, the first of its kind ever conducted. The new treatment, which is published in the British Medical Journal, has been developed by researchers at Karolinska Institutet and has the potential to increase access to care for sufferers of BDD.
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