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Researchers at Karolinska Institutet and their colleagues in Germany, the USA and Finland have studied the safety of very long-term antipsychotic therapy for schizophrenia. According to the study, which is published in the scientific journal World Psychiatry, mortality was higher during periods when patients were not on medication than when they were.
Patients with the inflammatory bowel disease ulcerative colitis have a higher risk of dying from colorectal cancer, despite modern therapy, even though the risk has declined in recent years. This is according to a new study published in the scientific journal The Lancet by a team of Swedish and Danish researchers.
A recent paper published in Science Advances by scientists at Karolinska Institutet in a large joint effort with Hungarian, Japanese, Swedish and American researchers demonstrates a previously unknown mechanism by which cells can protect proteins from irreparable damage by oxygen. Because this damage occurs in diseases such as cardiovascular, neurodegenerative conditions and cancer, the mechanism helps us to better understand these diseases.
Meeting at IMM with WHO Network for Chemical Risk Assessment working group for Community of Trainers.
Open rehersal 20 january 2020. No previous choir experience is required.
Researchers at Karolinska Institutet have developed a method based on artificial intelligence for histopathological diagnosis and grading of prostate cancer. The AI-system has the potential to solve one of the bottlenecks in today’s prostate cancer histopathology by providing more accurate diagnosis and better treatment decisions. The study, presented in The Lancet Oncology, shows that the AI-system is as good at identifying and grading prostate cancer as world-leading uro-pathologists.
Professor Sten Eirik Waelgaard Jacobsen, Karolinska Institutet and University of Oxford, was elected member of the Academy's Class for medical sciences on November 27, 2019.
Annika Hanberg, IMM, Programme director for the ToxMaster programme, was awarded ”Mäster 2019” by the Student Union at KI Medicinska Föreningen at their Lucia ball on the 13 December 2019.
Arne Holmgren, Senior Professor at Karolinska Institutet, died on January 6, 2020, 79 years old. Dr. Holmgren was widely known as one of the groundbreaking scientists establishing the rapidly growing field of redox biology.
Using a trick involving detergent and mass spectrometry, a research group has been able to wash and weigh protein molecules to determine which lipids make the protein work. The findings may help design molecules that stick to individual membrane proteins and pave the way for the development of new drugs including antibiotics and cancer therapies. The study is published in Angewandte Chemie International Edition.
From 2020, new prices for software licenses will apply as a result of updates and adjustments in the agreements with Karolinska Institutet's licensing partners.
From the jubilee year of 2010 and onwards, Karolinska Institutet awards medals to people who have made special efforts in support of KI's activities. There are three categories: the Gold Medal, the Large Silver Medal and the Silver Medal. Medals are awarded in conjunction with various academic ceremonies.
Researchers at Karolinska Institutet have come one step closer toward understanding how the part of our brain that is central for decision-making and the development of addiction is organized on a molecular level. In mouse models and with methods used for mapping cell types and brain tissue, the researchers were able to visualize the organization of different opioid-islands in striatum. Their spatiomolecular map, now in Cell Reports, may further our understanding of the brain’s reward-system.
Researchers at Karolinska Institutet have deciphered the diabetogenic role of a certain type of calcium channel in insulin-secreting beta cells. The researchers believe that blockade of these channels could be a potential new treatment strategy for diabetes. The study is published in the scientific journal PNAS.
Christina H. Opava summarized her career at KI in an entertaining talk prior to her retirement, led by Yvonne Enman, journalist and honorary doctor at KI.
Systembolagets Alkoholforskningsråd has awarded projects grants to four research projects at the Department of Global Public Health.
Researchers at SciLifeLab report in the journal Science that they have created a detailed blood atlas of the proteins in human immune cells. The open-access database offers medical researchers an unprecedented resource in the search for treatments for diseases.
Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. The researchers also show how glutamine levels can alter gene expression in several different cell types. However, more research is needed before glutamine supplementation may be recommended as a treatment for obesity. The study is published in the journal Cell Metabolism.
During one of few sunny days in November, about 290 Alzheimer researchers and other interested people from all over Sweden gathered in Aula Medica. It was Center for Alzheimer Research that had invited to the Swedish Meeting for Alzheimer research on 20 November.
Researchers at Karolinska Institutet, together with colleagues from the EU-funded project HUMAN, recently published a study on a new animal model for studies of human lipoprotein metabolism and pharmacodynamics. The study is a result of the EU project HUMAN using a new animal model and new technologies to study aging and cardiometabolic diseases.
Congratulations to Associate professor Susanna Brighenti at CIM who receives research grants for her group´s studies on new concepts for host-directed therapy in tuberculosis.
She receives the grant for ”New diagnostic tools and treatment for Alzheimer's disease, traumatic brain injury and small vascular disease” and it is distributed over three years.
Cognitive Behavioural Therapy (CBT) for patients with social anxiety not only helps to reduce anxiety levels but also seems to protect against accelerated cellular ageing, a study involving researchers at Karolinska Institutet published in the journal Translational Psychiatry reports.
The search for a cure to AIDS has partly focused on ways to eradicate infected cells. Now, new research from Karolinska Institutet in Sweden and the University of Pennsylvania in the U.S. shows that this approach may not be necessary for a functional cure. In a study focusing on a subset of HIV-positive individuals who can live with the virus without needing treatment, the researchers found that these people’s lymphocytes suppress the virus but do not kill off infected cells.
High blood levels of the lipid lipoprotein(a) in people with type 1 diabetes add to the already elevated risk of developing cardiovascular disease, researchers from Karolinska Institutet report in a paper published in the prestigious journal Diabetes Care. Lipoprotein(a) levels should therefore be measured in patients with type 1 diabetes and form part of the total risk assessment, say the researchers.
Two KI researchers receive research project grant for international collaboration within rare diseases (EJP Rare diseases) from the Swedish Research Council.
Two researchers at Karolinska Institutet are awarded the Strategic Mobility Grant from the Swedish Foundation for Strategic Research (SSF). The aim of the SSF mobility programme is to increase exchange between Swedish universities and industry by funding researchers’ work with a project managed by the other part.
Jakob Wikström at KI is one of this year’s three Wallenberg Clinical Fellows. The purpose of the program is to encourage clinical research by Swedish physicians. The funding is for three years and is provided by the Marianne and Marcus Wallenberg Foundation.
This year's silver medals are awarded to senior professors Lena von Koch and Björn Klinge. The medal is awarded to a person who has made excellent efforts to support the activities of Karolinska Institutet. The medals are awarded in conjunction with the ceremony for Diligence and Devotion.
As part of the EU Horizon 2020 funded project IMPACT TB, a policy dialogue was held in Ho Chi Minh City, Vietnam. Knut Lönnroth, Kristi Sidney Annerstedt, Kerri Viney and Olivia Biermann of the Department of Global Public Health are involved in IMPACT TB.
Professor Christina Dalman from the EPiCSS Research Group participated in round-table discussions on current research on mental illness at the Ministry of Social Affairs on 20 November.
What do KI researchers Alicja Wolk, Peter Stenvinkel, and Magnus Ingelman-Sundberg have in common with historical super-celebrities such as Sigmund Freud and Albert Einstein? They are all on the highly cited researchers list of h-index 100 or more in Google Scholar.

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Researchers at Karolinska Institutet and from the Netherlands have developed a simple tool that shows the survival probability of a person with dementia disease over three years. This, they hope, will facilitate dialogue with the most seriously affected and help doctors and others plan the necessary care. The study is published today in the scientific journal Neurology.
KI takes part in many different strategic partnerships within Erasmus+. Some of them are presented here.
Researchers at Karolinska Institutet have developed a new method for identifying which proteins are affected by specific drugs. The tool and the results it has already generated have been made freely available online. The method is described in the scientific journal Nature Communications.
Tuberculosis is the world’s leading infectious killer. An estimated 3 million people with TB are never diagnosed and treated. To find those “missing” millions with TB, one strategy is to do active case-finding, also known as systematic community-based TB screening. A review published in BMJ Open explores the antecedents, components and influencing factors for active case-finding policy development and implementation.
Per Nilsson, at the Division of Neurogeriatrics, NVS, receives 1 000 000 SEK in grants from Torsten Söderberg's Foundation.
On the 29th of November 2019 the annual event ”Silvia Master Academy Day” took place. During a full day, Silvia Doctors, Silvia Occupational therapists and Silvia Physiotherapists with a master’s degree in dementia care from KI, met at the Silviahemmet foundation. The purpose is to share experiences, gain new knowledge and network.
Now you can see news and operating info directed to your institution, department or unit. When you are logged in, the news is displayed on the staff portal start page.
The Deutsche Tinnitus Stiftung Charité has announced the creation of “The Research Prize in Tinnitus and Hearing”, awarded to outstanding achievements in the research areas covering causes, early detection and therapy of tinnitus and hearing damage.
Karolinska Institutet’s Committee for Higher Education has decided on changes to the alternative admissions process for the dental programme (TAPIL) for 2020.
Proceeds from recyclable cans and bottles in Biomedicum reached over 10 000 SEK!
Researchers from Karolinska Institutet participate in capacity building projects fincanced by Erasmus+
Four researchers at Karolinska Institutet have been granted a total of SEK 28 million in additional funding from the Knut and Alice Wallenberg Foundation (KAW). Two of these researchers are also promoted from Wallenberg Academy Fellows (WAF) to Wallenberg Scholars.
When Nobel prize winner Michael Kremer initially looked at the data of his now famous 1990s Kenya school study, he felt shocked and disappointed. The data showed that more textbooks did nothing to improve educational outcomes, contrary to what most researchers believed. But rather than succumbing to disillusionment, Kremer dug deeper into Kenya’s schooling system to uncover what measures truly did make an impact and found his answer: targeted help for weak students.
KI researcher Thomas Gustafsson, professor at the Department of Laboratory Medicine / Division of Clinical Physiology and Stefan Arver, Associate Professor at the Department of Medicine and Chief Physician at ANOVA Karolinska University Hospital Huddinge, are responsible for a study examining changes in muscle mass, muscle composition and strength in transgender persons during hormone treatment.
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2019-05-07