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Tips from Grants Office about current calls.
The CEPEH EU project organised its kick-off meeting on 15-19 December 2019 in Nottingham, United Kingdom. The aim of CEPEH strategic partnership is to co-design and implement new pedagogical approaches and in particular chatbots for European Medical and Nursing schools.
Ann Nordgren, Adjunct Professor at Karolinska Institutet, has in her position as coordinator of the working group predisposition within the Childhood Tumor Bank (BTB) - Genomic Medicine Sweden (GMS), working committee (AU) Childhood cancer, been awarded clinical project grant amounting to SEK 15.000.000 from the Swedish Childhood Cancer Fund.
The Swedish organisation Psykiatrifonden has just announced which projects will receive research funding by money earmarked for suicide preventative research donated by Suicide Zero. Lotfi Khemiri at Karolinska Institutet is responsible for one of the projects and is studying the connection between substance abuse and risk of suicide.
Hi Médoune Sarr, PhD-student at the Division of Neurogeriatrics. On February 28 you will defend your thesis ”A star is born: Development of NT* as a biotechnological tool based on the mechanism of pH dependent dimerization of the spidroin N-terminal domain”, what's the main focus of the thesis?
On May 15-16, 2020, The European Conference on Rare Diseases & Orphan Products (ECRD) will be held at the Stockholm fair in Älvsjö. The conference brings together over 800 participants from more than 50 countries. Abstract deadline is February 10.
A research residency (forskar-ST) provides financial support for a period of research during a clinical residency, and is available to all registered doctoral students on a residency programme within Region Stockholm.
The name changes have also been implemented in the premises booking system TimEdit, as well as in the overview on the web.
Dear LIME colleauges! In this first LIME Newsletter for 2020 I would like to take the opportunity to summarize the past year and begin by thanking you all for your contributions to the “inner and outer life” of the department in large and small matters.
Warmly welcome to nominate candidates for the yearly award ”Teacher of the Year - 2019” - ”Årets lärare - 2019” at the Department of Neuroscience.
Researchers worldwide are trying to develop a vaccine and antiviral treatments against the new corona virus spreading in China. At Karolinska Institutet, virus researchers Ali Mirazimi and Matti Sällberg are working to develop a prototype vaccine against the virus. But vaccine development takes time, and it will likely take at least six to nine months before an application for clinical studies can be filed and another two to three years before a vaccine could be ready for the public.
In response to the coronavirus outbreak, the Commission has launched a request for expressions of interest entitled “SC1-PHE-CORONAVIRUS-2020: Advancing knowledge for the clinical and public health response to the 2019-nCoV epidemic”, with a budget of €10 million.
Babies born with low birth weights are more likely to have poor cardiorespiratory fitness later in life than their normal-weight peers. That is according to a study by researchers at Karolinska Institutet in Sweden published in the journal JAHA. The findings underscore the importance of prevention strategies to reduce low birth weights even among those carried to at term delivery.
When Human Immunodeficiency Virus Type 1 (HIV-1) infects a cell, the virus often becomes invisible to both the immune system and drugs. Now research from Karolinska Institutet shows that the integrated virus mimics a specific chromatin structure that lets the virus sequence remain accessible while preventing production of new viruses.
In a recent study, researchers from the Karolinska Institutet show that the estrogen receptor beta (ERß) affects nerve signals in the part of the brain that controls locomotor activity. The results highlight the importance of ERß and the female sex hormone estrogen in brain development and function, and that an imbalance of the hormone could contribute to neuropsychiatric disorders.
The Play area will be closed 07:00-16:00.
The Play area in Box gym will be closed 07:00- 16:00 due to construction work.
Tuesday February 4 - Thursday February 6, the ball court "Play" will be closed due to construction work between 07:00 and 16:00.
A clinical phase I study led by the Public Health Agency of Sweden and researchers from Karolinska Institutet shows that a new vaccine for pertussis (whooping cough) given as drops into the nose is more efficacious than the current vaccine. The results of the study are presented in The Journal of Clinical Investigation. The vaccine will now be evaluated in a larger phase II clinical trial.
April 24th researchers at MAXIV will give an introduction in how to use MAXIV in medical research.
Researchers at Karolinska Institutet have mapped how different nerve cells in the brain area striatum process information to plan and execute our movements at just the right time and with the right vigour. The results, presented in the journal Cell Reports, show that different cell types in the striatum receive signals from completely different parts of the cerebral cortex and thus respond to different types of information.
The new corona virus continues to spread despite significant measures taken by the authorities in China to stop the outbreak. However, this time the fast response coupled with increased knowledge about the nature of the virus means the world is better placed to handle the outbreak compared to 18 years ago when SARS caused widespread concern, says virus researcher Ali Mirazimi, adjunct professor at the Department of Laboratory Medicine at Karolinska Institutet.
Tips from Grants Office about current calls
Researchers from the Teixeira Lab in collaboration with the Ruas and Stevens Labs at Karolinska Institutet have identified that molecular weight, nuclear import rate as well as the width of the muscle fibers are the key factors behind the transport of proteins within muscle cells. The study is published in PNAS and provides engineering parameters for gene therapies in skeletal muscle.
A multiple organ-on-chip platform developed by researchers at KTH Royal Institute of Technology, Karolinska Institutet and Harvard University could drastically accelerate drug testing. The technology, described today in Nature Biomedical Engineering, provides accurate predictions of drug effects prior to clinical testing.
On February 17 2020 The Swedish Ministry for Foreign Affairs changed their travel recommendations and now advise against all travels to the Hubei province in China, the region hardest hit by the new corona virus outbreak. The ministry also advices against non-essential travels to China except for Hongkong and Macao. Staff members and students should follow the recommendations of the responsible authorities.
Bo Runeson and his colleague Seena Fazel from University of Oxford has written a review article about the current state of research on suicide prevention. The article was published in New England Journal of Medicine.
A new digital tool that tailors specific questions based on a patient's medical history could improve the safety of diagnosis and effectiveness of care, according to a new study at Danderyd Hospital and Karolinska Institutet published in BMJ Open.
Researchers at Karolinska Institutet in Sweden have revealed a new principle of organisation which explains how locomotion is coordinated in vertebrates akin to an engine with three gears. The results are published in the scientific journal Neuron.
Tips from Grants Office about current calls
More than 200 people have died and thousands more have been sickened by the new corona virus spreading in China. A few cases have been confirmed outside China, and the World Health Organization is closely monitoring the situation. How worried about a new pandemic should we be? Virus researcher Ali Mirazimi, adjunct professor at the Department of Laboratory Medicine at Karolinska Institutet, gives us his perspective.
Two researchers at Karolinska Institutet have been awarded funds from the Sjöberg Foundation. The foundation promotes cancer research, and research on health and the environment.
After years of research on cell surface receptors called Frizzleds, researchers at Karolinska Institutet provide the proof-of-principle that these receptors are druggable by small molecules. The results, which are published in the scientific journal Nature Communications, open for new strategies to treat different types of cancer.
FM and KI Occupational Health Care Service are organising ergonomics lectures for Biomedicum staff in February, on the topic Good Workplace Ergonomics.
Additional cardiovascular Rescue (CPR) training sessions for Biomedicum staff will be offered in February and March 2020.
Abdominal obesity not only increases the risk for a first heart attack or stroke, but also the risk for recurrent atherosclerotic cardiovascular disease, according to a study by researchers at Karolinska Institutet published in the European Journal of Preventive Cardiology.
Endogenous proteins that play a vital part in allergies and parasitic infection can prevent the immune system from wrongly attacking the body and causing inflamed joints, a study from Karolinska Institutet published in the scientific journal PNAS reports. The researchers hope that the results will give rise to new drugs for rheumatoid arthritis.
Welcome to "Student - get inspired by a professor", a series of lunch seminars with different interesting themes.
If you want to attend a congress or conference, you can apply for grants from the TA Fund. The purpose of the fund is to promote and stimulate skills development for TA staff at Karolinska Institutet. Please mark your application 2-128/2020. More information and application forms at the web page.
The call is open for researchers with research activities linked to one of the departments at Campus Flemingsberg.
A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia (AML), one of the most common forms of blood cancer. This is the conclusion of a study in mice and human blood cells performed at Karolinska Institutet and SciLifeLab and published in the medical journal EMBO Molecular Medicine. The researchers will now launch a clinical study to test the new combination treatment in patients.
The transcription factor DAF-16/FOXO mediates a wide variety of aging-preventive responses by driving the expression of stress-resistance and longevity promoting genes. Ilke Sen and other members of the Riedel lab could show that transcriptional initiation at many DAF-16/FOXO target genes depends on dephosphorylation of SPT-5 by Protein Phosphatase 4.
KI researcher Emma Andersson receives Swedish Foundations' Starting Grant 2019 for research in developmental biology.
In a new study published in Circulation Research, researchers at Karolinska Institutet show that the enzyme PCSK6, the proprotein convert subtilisin / kexin 6, plays a key role in vascular disease. The findings give hope that PCSK6 may become a future target molecule for the development of anti-vascular disease drugs.
The NU conference is Sweden's largest meeting place for the development of higher education. It will take place 7-9 October 2020 at several higher education institutions at Campus Flemingsberg, including Karolinska Institute. You as an employee at KI have the opportunity to get the conference fee paid.
The bicycle garage in Biomedicum needs to be tidied up and in order to do so we will need to empty it entirely.
Tips from Grants Office about current calls
In a new study published in Nature Communications, researchers at Karolinska Institutet show that MAIT cells (mucosa-associated invariant T cells), part of the human immune system, respond with dynamic activity and reprogramming of gene expression during the initial phase of HIV infection. The study fills a knowledge gap, as previously there has been a lack of awareness of the function of MAIT cells during this particular phase.
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