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In contrast to what has been previously believed, development of blood stem cells to mast cells, a type of specialised immune cell, does not depend on a growth factor called stem cell factor. This has been demonstrated in a new collaborative study by researchers at Karolinska Institutet and Uppsala University, and published in the scientific journal Blood. The results could pave the way for new treatments for certain types of blood diseases.
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Obesity and reduced insulin sensitivity are common in polycystic ovary syndrome, PCOS. New research based on animal studies, and to be published in the journal PNAS, reveals that the hormone adiponectin can protect against these changes.
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The dynamics among certain so-called G protein-coupled receptors, of vital importance for the function of cells in the body, are different than previously believed. This has been reported by researchers from Karolinska Institutet in the journal Nature Communications. As these types of receptors are the target for many different medicines, the new finding opens the doors to completely new opportunities within pharmacology and pharmaceutical development.
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Infections in surgically implanted heart valves are more common in patients who have been given a biological prosthetic valve than in those with a mechanical one, a study from Karolinska Institutet published today in the journal Circulation shows.
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SciLife Lab fellow and MTC Assistant Professor Vicente Pelechano is featured in "medarbetarporträtt" this month - a video interview outlining his research at Karolinska Institutet and SciLife.
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Many jobs, medical and otherwise, might one day be performed using artificial intelligence. According to a new study in Acta Orthopaedica by researchers at Karolinska Institutet in collaboration with the Royal Institute of Technology and Danderyd Hospital in Sweden, self-learning programmes can already find fractures with the same accuracy as orthopaedists.
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Acupuncture has no effect on involuntary childlessness caused by polycystic ovary syndrome (PCOS), the most effective treatment for PCOS being the drug chlomiphene, a joint international study conducted at Heilongjiang University of Chinese Medicine, China, reports. The study, which involved the participation of researchers at Karolinska Institutet, is published in JAMA.
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A high percentage of KIF1Bβ means a greater chance of the tumour spontaneously regressing and disappearing. These are the results of a study by Karolinska Institutet (KI) and the Ludwig Institute for Cancer Research Ltd. The study is to be published in the scientific journal Genes and Development.
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In memory of Professor Lennart Philipson, the board of the Malin and Lennart Philipson Foundation awards a prize and grant for molecular biomedical research with the aim to help young, promising scientists to establish an independent research group after their postdoc training. This year’s awardee is KI researcher Dr Volker M. Lauschke.
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With Karolinska Institutet’s major investments in infrastructure, especially with the new research buildings, the rents are now rapidly increasing. In addition, the laboratory-intensive activities will be required to pay more than others, from 2018, which has given rise to criticism from the academic researchers and scientists.
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It has long been assumed that chronic nerve pain is caused by hypersensitivity in the neurons that transmit pain. Researchers at Karolinska Institutet in Sweden now show that another kind of neuron that normally allows us to feel pleasant touch sensation, can switch function and instead signal pain after nerve damage. The results, which are presented in the journal Science, can eventually lead to more effective pain treatments.
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What happens in the brain when we see other people experiencing a trauma or being subjected to pain? Well, the same regions that are involved when we feel pain ourselves are also activated when we observe other people who appear to be going through some painful experience. This is shown in a study from Karolinska Institutet published in Nature Communications. But we are sensitive to different degrees to learning fear from other people and one explanation would appear to be found in the endogenou
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As a young researcher, Liv Eidsmo, was at first scared by the critical culture at her new workplace – since then she has learnt to appreciate it.
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Everyone worries at times, but when thoughts of disaster get the upper hand, it might be a good idea to seek help. Researchers at Karolinska Institutet knows how we all can become a little calmer.
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