News archive

The amount of time Swedish teenagers spent on social media could not be linked to symptoms of depression or anxiety five years later, in a new study from Karolinska Institutet published in the Journal of Adolescent Health.

Every year, the Swedish Asthma and Allergy Association’s Research Fund awards the Kerstin Hejdenberg Scholarship to doctoral students conducting research on allergic diseases in children. This year, three of the scholarship recipients are affiliated with Karolinska Institutet.

The aim of a systematic review is to summarize the currently available evidence for a given research question. In addition, meta-analysis is often used to statistically combine results from multiple studies. This report provides a methodological guidance for conducting systematic reviews and meta-analyses in environmental epidemiology, with a particular focus on etiological research questions.

Children with asthma and allergies who live with one or more cats do not experience worse asthma outcomes than children without cats at home. This is according to a comprehensive Swedish registry study from Karolinska Institutet, published in Frontiers in Allergy.

People with celiac disease and dermatitis herpetiformis have a slightly increased risk of cardiovascular disease, certain types of blood cancer, and premature death. This is shown by a large U.S. registry study led by researchers at Karolinska Institutet. The results are published in the journal The Lancet Regional Health – Americas.

In a new thesis from Karolinska Institutet, PhD student Xiaoyi Ji investigated the generalisation and robustness of AI models for computational prostate cancer pathology across multiple sources of variation and examined possible strategies for improvement.

How can artificial intelligence help researchers understand complex disease processes and identify previously hidden patterns? That was the focus when Fang Fang, professor at the Institute of Environmental Medicine, Karolinska Institutet, was interviewed for the internationally renowned medical journal JAMA’s podcast series JAMA+ AI Conversations.

On May 12, Jonas F Ludvigsson, professor at the Department of Medical Epidemiology and Biostatistics, and senior pediatrician at Örebro University Hospital was re-elected for another 3 years as Scientific Chair of the Swedish Society of Medicine.

Associate Professor Sara Hägg from the Department of Medical Epidemiology and Biostatistics has been elected to join the Academy of Geroscience.

The occurrence of microscopic colitis in Sweden has risen steadily over the past decades, according to a new study from Karolinska Institutet published in Clinical Gastroenterology and Hepatology. The findings show that the disease is more common than previously recognised and affects mainly older adults, especially women.

Adopted children who have grown up in more favourable family environments than their siblings are at lower risk of mental health issues, criminality and social problems – benefits that, in some cases, extend to the next generation. These are the findings of a new study of Swedish siblings published in The BMJ.

The Centre for Health Crises at Karolinska Institutet works to ensure that experience gained from working on health crises internationally can be transformed to benefit Sweden’s crisis preparedness. As part of this, they have conducted a one-day training excerise on global outbreak epidemiology in collaboration with the Swedish Red Cross. Its aim is to provide further education for people who have worked on projects abroad.

Living with a dog does not seem to worsen long‑term asthma severity in children with allergic asthma, but may increase the risk of asthma exacerbations slightly, according to a study from Karolinska Institutet in Sweden that has been published in Journal of Allergy and Clinical Immunology: Global.

Although people in Japan tend to live long lives, this does not necessarily mean they are healthier than other populations. New research from Karolinska Institutet and collaborators shows that Japanese and Swedish older adults have a similar number of healthy life years – if ‘healthy’ is defined as living at home without the need for formal elder care. However, mortality among individuals receiving elder care is lower in Japan than in Sweden.

Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition that affects how the brain develops and functions. It’s usually noticed in childhood, and more than half of those diagnosed keep experiencing symptoms as adults. Medicines for ADHD can reduce these symptoms, but lasting benefits depend on continuing the medication regularly.

Precancerous colorectal lesions, or dysplasia, in patients with inflammatory bowel disease (IBD) confer markedly different risks of future colorectal cancer depending on dysplasia grade, according to a comprehensive registry study from Karolinska Institutet, Sweden, and NYU Grossman School of Medicine, New York, published in Clinical Gastroenterology and Hepatology.

Two out of three adolescents with irritable bowel syndrome (IBS) start adulthood without the disease, according to a long-term study published in Gastroenterology by researchers at the University of Gothenburg and Karolinska Institutet. The researchers also note that several factors in adolescence which increase the risk of adult IBS can be influenced.

Prolonged exposure to air pollution can be linked to an elevated risk for serious neurodegenerative diseases like ALS and seems to speed up the pathological process, report researchers from Karolinska Institutet in Sweden. The study is published in the journal JAMA Neurology.

A new study shows that internet-delivered cognitive behavioural therapy (ICBT) can effectively reduce asthma-related anxiety in adults with asthma. Participants who received ICBT reported less anxiety related to their asthma, better asthma control, higher quality of life, and fewer avoidance behaviours compared to those who received standard care. Lung function was not affected by the treatment, indicating that it is safe and can be used as a complement to medical asthma treatment.

The Epilepsy Foundation (Stiftelsen Epilepsifonden) is awarding a grant of SEK 400,000 to the research project “MAP-KETO,” which is investigating the effects of a ketogenic diet on children with drug-resistant epilepsy.

Artificial Intelligence that detects breast cancer, enables medical imaging in low-resource countries and that identifies the patients who require advanced treatment even at the point of diagnosis – these are just a few examples of AI research at Karolinska Institutet that is impacting an entire world. Parts of this work were presented during the conference AI@KI, Advances in Artificial Intelligence at Karolinska Institutet, on 2 December.

What did we learn during the pandemic and how do we prepare for the next one? That was the theme when representatives from academia, healthcare, authorities, politics and media met during two intensive half-days at an event called Don't let the Lessons from the Pandemic go to Waste, to look back but above all to look ahead. Most agreed that we have learned a lot and now have greater crisis awareness, but also that there is still much to do if we want to tackle the next health crisis even better.

Depression is one of the most common mental health conditions, and some people recover with medications or therapies. However, for some individuals, treatment does not work, even after several attempts. This harder-to-treat form of depression is known as treatment-resistant depression (TRD). People affected by TRD often experience more severe and long-lasting symptoms, lower quality of life, and more physical health problems than other depression cases without TRD.

Lung cancer is the leading cause of cancer-related death worldwide, largely due to late detection, when treatment options are limited. Detecting the disease earlier and tailoring treatments more precisely are essential to improve survival and quality of life for patients.

Breast cancer is the most common form of cancer among women, with around 9,600 new cases diagnosed each year in Sweden. The breast cancer can spread to other parts of the body, and the first spread is usually to the lymph nodes that run from the breast to the armpit on the same side. Knowing whether the cancer has spread to these lymph nodes is crucial, as it helps determine the most appropriate treatment.

A new thesis from Karolinska Institutet studied how mental health problems run in families. Using nationwide Swedish registers, the researchers followed millions of parents and their children over decades, revealing several important findings about how and why mental health problems pass from parents to children, and importantly, how to interrupt this cycle.

A new thesis from Karolinska Institutet focuses on advanced statistical methods to better predict long-term patient outcomes, supporting healthcare decision-making. The application focused on chronic myeloid leukemia with the goal to inform clinical and policy insights.

A large international study led by researchers at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, shows that major depressive disorder (MDD) not only increases risk for a wide range of diseases and social problems, but is also partly driven by factors such as loneliness, obesity, smoking, and chronic pain.

According to a study by Karolinska Institutet, nearly three times as many people under the age of 50 in Sweden are diagnosed with colorectal cancer today compared with the early 1990s. The study also shows that mortality is elevated in both younger and older patients for up to ten years after diagnosis.

As ADHD medication use has surged in Sweden over the past decades, evidence is needed on whether the benefit of the medication remains consistent. A new study from Karolinska Institutet, published in JAMA Psychiatry, shows that while ADHD medication still helps reduce the risk of self-harm, unintentional injuries, traffic accidents, and criminal behavior, its protective effects have diminished over time as ADHD medication use has broadened to a wider group of patients.

Suganthi Jaganathan researches air pollution in India. Among other findings, she has shown that poor air quality caused 16.6 million deaths in India over a ten-year period.

Infants who survive serious health problems in the first few weeks of life have a higher risk of dying during childhood and adolescence compared to children who were healthy as newborns. This is according to a new study from Karolinska Institutet published in the journal JAMA Pediatrics.

Prostate cancer is one of the most common cancers in men globally. Diagnosing prostate cancer involves examining tissue samples under a microscope, a process that can be inconsistent and yield different results by different pathologists for the same sample, potentially affecting patient treatment. In some unclear cases, extra testing called immunohistochemistry (IHC) is used, but it adds cost, time, and lab work.

People with an autism diagnosis are at a higher risk of developing Parkinson’s disease early in life, a large-scale study from Karolinska Institutet published in JAMA Neurology reports. The researchers believe that the two conditions can share underlying biological mechanisms.

Welcome to Anna Zettergren's defense of the thesis ”Tobacco Exposure and Health – From Fetal Life to Adulthood”.

A new study in the European Heart Journal shows that people who develop type 1 diabetes in adulthood have an increased risk of cardiovascular disease and death, and that those diagnosed later in life do not have a better prognosis than those diagnosed earlier. The study, conducted by researchers at Karolinska Institutet, points to smoking, poor glucose control and obesity as the main risk factors.

Pregnant women with metabolic dysfunction-associated steatotic liver disease (MASLD) have an increased risk of giving birth prematurely and the risk increase cannot be explained by obesity, according to a new study from Karolinska Institutet published in the journal eClinicalMedicine.

The Consortium Global IBD Visualization of Epidemiology Studies in the 21st Century (GIVES-21) now publish data on the global prevalence of inflammatory bowel disease (IBD) in Nature. Researchers from Karolinska Institutet have contributed to the study. While the number of people with incident IBD is relatively constant in Sweden, the prevalence is increasing and 1 per cent of the Swedish population is now estimated to have IBD.

A higher tax on cigarettes in low and middle-income countries can help to reduce child mortality, especially amongst the poorest children, a new study led by researchers at Karolinska Institutet and published in The Lancet Public Health suggests.

Professor Jonas F Ludvigsson at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, and Örebro University Hospital has been awarded the Solstickepriset 2025.

KI Professor Anna Mia Ekström joins the KIB podcast in a conversation about the Face of AIDS Film Archive, the unique film archive documenting the global HIV epidemic 1986-2021. We talk about the importance of the current political landscape in the fight against HIV and AIDS, the results achieved in terms of treatment and the very real risk that these results will be reversed. We talk about the role of documentation and activism: ‘We don't see that today [...] and we know that silence kills.'

The Swedish National Patient Register (NPR) has long been a cornerstone for epidemiological research. Researchers at Karolinska Institutet have published a new review examining the validity of the register and found that it is good for most diagnoses and very good for surgical procedures.

The European Renal Association (ERA) just announced that Dr. Anne-Laure Faucon will receive the “ERAC Award for Young Investigators – Young Nephrologist”. The prize is awarded to a young nephrologist/researcher who has made a scientific contribution in the field of nephrology.

Researchers at Karolinska Institutet have demonstrated how specific biomarkers in the blood can predict the development of dementia up to ten years before diagnosis, among older adults living independently in the community.

This week, the third edition of the book “To start a research career within medicine and health” ("Att börja forska inom medicin och hälsa") is released. Author is Jonas F Ludvigsson, pediatrician and professor at the Department of Medical Epidemiology and Biostatistics and the book is aimed at doctoral students and prospective researchers in medicine and health.

In a new study, researchers from Karolinska Institutet have shown that so-called interval cancers, which are detected between two screening sessions, account for a significant proportion of breast cancer cases and that certain risk factors may increase the likelihood of developing this type of cancer. The study was published in the journal JAMA Oncology.

The debate on nature versus nurture has never ceased, particularly in discussions about neurodevelopmental conditions (NDCs) such as autism and attention-deficit hyperactivity disorder (ADHD). These lifelong conditions emerge in childhood, and while they mostly have genetic nature, environmental factors may play a role.

Elevated concentrations of fluoride can occur in well water, and in some countries, it is added to drinking water to counteract caries in the population. A study from Karolinska Institutet now supports a few previous studies indicating that exposure to fluoride during the fetal stage or early childhood may impair cognition in children. The study is published in the journal Environmental Health Perspectives.

A new study from Karolinska Institutet shows that severe mental illness is more common in patients with chronic kidney disease and negatively affects their health. The study has been published in the American Journal of Kidney Diseases.

A new thesis from Karolinska Institutet aims to advance our understanding of the bidirectional relationship between inflammatory bowel disease (IBD) and chronic kidney diseases (CKD) through large-scale epidemiological studies utilizing real-world data.