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Researchers at Karolinska Institutet have been looking at how movement shapes our senses and how sensory and motor processes are both affected in Parkinson’s disease. In a study published in Nature Communications, de la Torre-Martinez et al, show that movement reduces the responses to sensory input and that both sensory and motor processes are altered in an animal model of Parkinson’s disease.
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Christer Halldin, Professor at the Department of Clinical Neuroscience at Karolinska Institutet, and his team have been awarded a grant of approximately 860,000 US dollars for a project up to three years, from the Michael J. Fox Foundation for Parkinson’s Research (MJFF).
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New study from researchers at Karolinska Institutet published in Science Advances show that inactivation of a protein complex that controls gene repression leads to loss of neuronal identity of dopamine-producing cells and to motor symptoms typical of Parkinson's disease.
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Medication for Parkinson's disease reduces many of the symptoms that affect patients, but often the problems associated with impaired balance and increased risk of falls and injuries remain. A new study in the journal NPJ Parkinson's Disease provides an in-depth picture of balance training as a treatment for Parkinson's. The partly disappointing results suggest that exercise programmes may need to be intensified or personalized to a greater extent, and that more research is required.
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Konstantinos Meletis, Professor in the Department of Neuroscience, has been awarded a grant of approximately 1.73 million US dollars for three years from the Aligning Sciences Across Parkinson’s (ASAP) initiative.
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Per Svenningsson has been awarded a grant of approximately 1.86 million US dollar for three years, from the Aligning Science Across Parkinson’s (ASAP) initiative for an ambitious, multidisciplinary effort to study how abnormal protein aggregates may spread from the gut to the brain to drive the early stages of Parkinson’s disease. The total award is 8.9 million US dollar grant for three years.
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Professor Per Svenningsson at Karolinska Institutet receives funding for a five-year research project of 38 million SEK from Nordstjernan Holding AB and the Axel Johnson Group. The investment goes to fundamental research on the onset of Parkinson's disease and to clinical studies to improve treatment and slow down the course of the disease.
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People who consume high levels of vitamin C and E in their diet may have a lower risk of Parkinson’s disease than people who get only small amounts of these nutrients, according to a new study from University of Milano-Bicocca, Italy, and Karolinska Institutet. The study was published in Neurology.
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Hi Hanna Johansson, PhD student at the Division of Physiotherapy, NVS. On October 23 you will defend your thesis “Balance and gait in Parkinson’s disease : from perceptions to performance”. What’s the main focus of the thesis?
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The focus of Johanna Sieurin's thesis was to investigate the relationship of personality and stress with subsequent risk of Parkinson’s disease (PD).
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Researchers at Karolinska Institutet and the University of North Carolina have mapped out the cell types behind various brain disorders. The findings are published in Nature Genetics and offer a roadmap for the development of new therapies to target neurological and psychiatric disorders. One interesting finding was that cells from the gut's nervous system are involved in Parkinson's disease, indicating that the disease may start there.
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A new study by researchers at Karolinska Institutet shows that the protein alpha-synuclein, which accumulates in patients with Parkinson’s disease, occurs bound to lipoprotein particles in cerebrospinal fluid, which may explain how the disease spreads in the nervous system. The study is published in the scientific journal PNAS.
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A study by researchers at Karolinska Institutet and the University of Copenhagen published in Nature provides new and important knowledge about how the brain controls locomotion. In research on mice, scientists have discovered that specific start cells in various locations in the brainstem control whether the mouse walks or runs. This research may lead to new treatments for diseases and injuries that adversely affect locomotion.
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Although Parkinson’s disease is often associated with motor symptoms such as stiffness, poor balance and trembling, the first symptoms are often sensory and include a reduced sense of touch and smell. In a study on mice, researchers at Karolinska Institutet have now been able to identify neural circuits and mechanisms behind this loss of sensory perception. The study, which is published in the scientific journal Neuron, may open avenues to methods of earlier diagnosis.
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Researchers at Karolinska Institutet have made significant progress in the search for new treatments for Parkinson’s disease. By manipulating the gene expression of non-neuronal cells in the brain, they were able to produce new dopamine neurons. The study, performed on mice and human cells, is published in the prestigious scientific journal Nature Biotechnology.
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09-06-2023