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When you hear the words mucus and snot, you might think of colds, snails or drooling babies. But the runny, sometimes sticky substance often plays a vital role in our lives. And mucus also has potential to be a medicine.

A new registry study from Karolinska Institutet and Tampere University shows that hospital admissions due to allergic reactions in children have increased in Finland while they have decreased in Sweden. The study, published in the journal Allergy, also shows that the incidence of anaphylaxis is higher in Finland than in Sweden.

When Inger Kull was a new nurse in the early 1980s, researchers were looking for risk factors. Today she is a professor and prefers to talk about health factors. Thirty years of research on the Bamse-children have provided answers to many questions, but not the most difficult: Why do children develop allergies?

In the healthcare setting, keeping things clean can be vital to prevent the spread of dangerous bacteria. But in a household, what’s best for your health – to live pretty dirty or to be a clean freak? Read our interviews with the researchers who have a pure interest in cleaning.

Meet Anna Smed Sörensen, research group leader at the Division of Immunology and Allergy, Department of Medicine, Solna.

The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis. Now, an article published in Science Immunology by researchers from Karolinska Institutet challenges this hypothesis by showing that mice with high infectious exposures from birth have the same, if not an even greater ability to develop allergic immune responses than 'clean' laboratory mice.

The Cancer and Allergy Fund has awarded a grant of SEK 4.2 million to 23 patient-end projects on cancer and allergies. Of these, fifteen researchers at nine departments at Karolinska Institutet are to share SEK 2.5 million.

Use of hazardous preservatives in chemical products has increased dramatically in the years 1995–2018. Several of these are potent skin sensitizers and may cause lifelong allergy that affects work ability and quality of life. A new study from the Institute of Environmental Medicine (IMM) draws attention to the need for action for protection of human health and the environment.

Infants who were given a taste of peanut, milk, wheat and egg from the age of three months had a lower risk of developing a food allergy at the age of three years than controls, reports a study by researchers from Karolinska Institutet in Sweden and the University of Oslo in Norway published in The Lancet.

The causes of complex diseases can be identified by representing them in the form of mathematically produced networks. This method was used to find bacteria that drive atopic dermatitis, for example.

Eleven researchers at five departments at Karolinska Institutet have received funding from Cancer- och Allergifonden (Cancer and Allergy Fund) for their point-of-care research projects on cancer and allergies. The researchers from Karolinska were allocated SEK 2.6 million. In total, the Fund distributed a total of five million SEK to Swedish cancer and allergy research.

Many diseases caused by a dysregulated immune system, such as allergies, asthma and autoimmunity, can be traced back to events in the first few months after birth. To date, the mechanisms behind the development of the immune system have not been fully understood. Now, researchers at Karolinska Institutet show a connection between breast milk, beneficial gut bacteria and the development of the immune system. The study is published in Cell.

In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient’s type of asthma. The study, which has been published in the American Journal of Respiratory and Critical Care Medicine, lays the foundation for a more personalized diagnosis and may result in improved treatment of severe asthma in the future.

With the help of algorithms, researchers at Karolinska Institutet in Sweden have identified markers that can differentiate between irritant eczema and contact allergy, two skin reactions that look similar but require different treatment. Their findings, which are published in the journal Proceedings of the National Academy of Sciences (PNAS), support the further development of an alternative to today’s diagnostic patch tests.

Cytokines are a type of proteins that are important to the signaling between cells in the body's immune system, for example in the case of an infection or injury. A new study in the Journal of Allergy and Clinical Immunology, by researchers researchers at Karolinska Institutet and Lund University, is now indicating that the cytokine interleukin(IL)-26 could be used as a biological marker (biomarker) for uncontrolled asthma in both adults and children.

In contrast to what has been previously believed, development of blood stem cells to mast cells, a type of specialised immune cell, does not depend on a growth factor called stem cell factor. This has been demonstrated in a new collaborative study by researchers at Karolinska Institutet and Uppsala University, and published in the scientific journal Blood. The results could pave the way for new treatments for certain types of blood diseases.

New research from Karolinska Institutet and the Stockholm South General Hospital shows that the alpha-gal carbohydrate, which is found in the tick intestine, can cause allergic reactions to red meat in bitten people.