News archive

Medical sleep treatment may reduce self-harm in young people with anxiety and depression, an observational study from Karolinska Institutet suggests. The risk of self-harm increased in the months preceding melatonin prescription and decreased thereafter, especially in girls. The study is published in The Journal of Child Psychology and Psychiatry.

The deadline for applying to the research school for clinicians in psychiatry (KI-Region Stockholm) is prolonged until 24th of March.

Rumours spread faster than ever nowadays thanks to social media, and it is easy to get carried away. Some people are also inherently more vulnerable to conspiracy theories. However, sceptics’ concerns should be addressed, not dismissed, say researchers who are studying people’s willingness to take different kinds of vaccines.

An online anonymous cognitive behavioural therapy (CBT) treatment program for individuals with a sexual interest in children showed good results in an English language pilot study. Now the CBT program for crime prevention also opens in Swedish, German, and Portuguese. The treatment program, which has been developed by researchers and psychologists at Karolinska Institutet, will be evaluated within the framework of an international research collaboration funded by the EU.

Beta blockers, which are widely used to treat heart conditions and high blood pressure, are associated with a lower risk of being charged with a violent crime, according to a new register-based study from Karolinska Institutet and the University of Oxford. The results have been published in PLOS Medicine.

Problems with managing anger can have severe consequences for the afflicted individual and their loved ones. A new study from the Centre for Psychiatry Research at Karolinska Institutet shows that four weeks of therapy delivered over the internet can help people with anger and aggression. The results have been published in the Journal of Consulting and Clinical Psychology.

The ADHD medication lisdexamfetamine was associated with the lowest risk of hospitalisation and death in people with amphetamine addiction, when medications generally used among persons with substance use disorders were compared. This is shown in a large registry-based study by researchers at Karolinska Institutet in Sweden in collaboration with the University of Eastern Finland and Niuvanniemi Hospital, published in JAMA Psychiatry.

Autistic young men and women are more affected by psychiatric conditions and have an increased risk of being hospitalized as a result of their mental illness compared with non-autistic people. Autistic women are particularly vulnerable. This is shown by researchers from Karolinska Institutet in a study published in JAMA Psychiatry.

Professor Mikael Landén was awarded the Swedish Society for Medical Research (SSMF) Jubilee Prize for his valuable findings within psychiatry research. This prestigious prize is SEK five million, intended for research. He will also be awarded a medal at the prize ceremony on 21 October.

Deep grief has both mental and physical health consequences for the sufferer that can take decades to heal. People can even die of grief. It is therefore important to try to alleviate the effects of severe grief, something that we in Sweden aren’t particularly good at.

Patient-initiated brief admission as a complement to outpatient psychiatric care is appreciated by nurses and patients, and can reduce levels of anxiety in people with emotional instability and self-harm, a new thesis from Karolinska Institutet reports.

Researchers at Karolinska Institutet in Sweden might have found an explanation for why people with self-injury behaviour generally feel less pain than others. The key seems to be a more effective pain-modulation system, a discovery that can benefit people seeking help for their self-harm. The findings are published in the journal Molecular Psychiatry.

Six predictors could help determine the amount of lithium needed to treat patients with bipolar disorder, according to a large study led by researchers at Karolinska Institutet in Sweden. The study, published in the journal The Lancet Psychiatry, also pinpoints genetic markers that seem to influence how quickly the body eliminates lithium from its system.

Children with migration backgrounds in Sweden are less likely than other children to receive recommended treatment for psychiatric diagnoses such as ADHD and depression, a paper from Karolinska Institutet published in the journal Epidemiology and Psychiatric Sciences reports.

Sexual and gender-based harassment in the workplace can contribute to the development of mental ill-health requiring treatment with antidepressants and anti-anxiety medication, a study from Karolinska Institutet in Sweden published in the journal Occupational and Environmental Medicine reports.

What does it mean to admit yourself as a patient? Maria Smitmanis Lyle, a PhD student at the Department of Clinical Neuroscience and Coordinator at the Centre for Psychiatry Research, who researches self-admission for children and adolescents, explains.

Use of assisted reproductive techniques (ART) does not lead to poorer mental health in children across adolescence and young adulthood, according to a large observational study led by researchers at Karolinska Institutet. The study, published in JAMA Psychiatry, found a slightly higher risk of obsessive-compulsive disorder for those born after ART but this was explained by parental background factors.

It remains a central challenge in psychiatry to reliably judge whether a patient will respond to treatment. In a new study published in the journal Biological Psychiatry, researchers from Karolinska Institutet in Sweden and the Max Planck Institute for Human Development in Germany show that moment-to-moment fluctuations in brain activity can reliably predict whether patients with social anxiety disorder will be receptive to cognitive behavioural therapy (CBT).

Patients with bipolar disorder who experience manic episodes are more likely to show abnormal brain changes over time, according to one of the largest longitudinal brain imaging studies in its field to date. The study, led by researchers at Karolinska Institutet and University of Gothenburg in Sweden, also confirms links between bipolar disorder and accelerated brain ventricle enlargement. The findings are published online in the journal Biological Psychiatry.

Traumatic experiences such as assault or a road accident can give rise to nightmares, flashbacks and other mental reactions, and accessible therapy is needed to prevent exacerbation of the problems. Researchers at Karolinska Institutet have now completed what could be the largest evaluation to date of internet-delivered trauma-focused CBT (iCBT-T) for people who have recently experienced trauma. The study, which is published in Psychological Medicine, shows promising results.

Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet published in The Lancet Psychiatry.

Social anxiety disorder can cause considerable suffering in children and adolescents and, for many with the disorder, access to effective treatment is limited. Researchers at Centre for Psychiatry Research at Karolinska Institutet and Region Stockholm have now shown that internet-delivered cognitive behavioural therapy is an efficacious and cost-effective treatment option. The study is published in the journal JAMA Psychiatry.

Obsessive-compulsive disorder (OCD) in children and adolescents is associated with impaired education and worse general health later in life. Access to specialist treatment is often limited. According to a study from Centre for Psychiatry Research at Karolinska Institutet and Region Stockholm, internet-delivered cognitive behavioural therapy (CBT) can be as effective as conventional CBT. The study, published in the prestigious journal JAMA, can help make treatment for OCD more widely accessible.

Researchers at the Centre for Psychiatry Research at Karolinska Institutet have completed a large study evaluating a screening instrument for assessing the risk of suicide in connection with a visit to an emergency psychiatric clinic. The researchers found a link between screening score and suicide risk a short time after the emergency visit. The study is published in the journal Psychological Medicine.

Individuals with high ADHD-traits that do not meet the criteria for a diagnosis are less able to perform tasks involving attentional regulation or emotional control after a sleepless night than individuals with low ADHD-traits, a new study from Karolinska Institutet published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging reports.

Depressed children and teenagers have an increased risk of suffering from premature death and a wide range of illnesses later in life. That is according to a large observational study by researchers at Karolinska Institutet in Sweden. The findings highlight the need to look for other potential diseases following childhood or adolescent depression. Other psychiatric conditions, such as anxiety and substance misuse, can explain part of the association. The study is published in JAMA Psychiatry.

It is a known fact that sexual minorities are at a higher risk of developing poor mental health, when compared to heterosexuals. The stigma that sexual minorities face has been regarded as potentially the primary cause of this. A new thesis from Karolinska Institutet offers an insight into how stigma-related factors may work in a broader socio-ecological system, considering the complex interaction between structural, interpersonal and individual factors.

Liu Yang from the research group Translational Psychiatry, the Department of Molecular Medicine and Surgery, will defend her thesis "Exploring the Gut-brain Axis in Attention Deficit Hyperactivity Disorder (ADHD)" on December 4, 2020. Main Supervisor is Catharina Lavebratt.

Worry about COVID-19 dominates some people’s lives in a way that has an impact on their health. A group of researchers at Karolinska Institutet in Sweden has developed a digital CBT programme that significantly reduced the participants’ unhelpful worry about the pandemic. The study is published in Psychotherapy and Psychosomatics and the programme is available through 1177 Vårdguiden.

Migrants from Africa and the Middle East and their children are more likely to be placed under compulsory care than the Swedish-born population when admitted to hospital for psychosis for the first time. That is according to a large, nationwide study by researchers at Karolinska Institutet in Sweden and University College London in the U.K., published in the journal Psychological Medicine.

The anaesthetic drug ketamine has been shown, in low doses, to have a rapid effect on difficult-to-treat depression. Researchers at Karolinska Institutet now report that they have identified a key target for the drug: specific serotonin receptors in the brain. Their findings, which are published in Translational Psychiatry, give hope of new, effective antidepressants.

Researchers at Karolinska Institutet have compared two ways of delivering cognitive behavioral therapy to treat people with health anxiety, a condition that may increase in the wake of COVID-19. Out of about 200 study participants, half received Internet-CBT and half received conventional face-to-face CBT. The results, published in JAMA Psychiatry, show that Internet-delivered treatment had comparable effects, and may serve as an alternative in helping people who are worried about their health.

Researchers at Karolinska Institutet show that different measures of psychopathology can be combined into a single factor, “p”, which predicts the patient’s prognosis and need of extra support. The general factor of psychopathology reflects the overall risk of adverse psychiatric outcomes with an accuracy equal to that currently used for intelligence, they report in a paper published in World Psychiatry.

A drug that lowers levels of the male hormone testosterone in the body reduces the risk of men with pedophilic disorder sexually abusing children, a study from Karolinska Institutet published in the journal JAMA Psychiatry shows.

Cognitive Behavioural Therapy (CBT) for patients with social anxiety not only helps to reduce anxiety levels but also seems to protect against accelerated cellular ageing, a study involving researchers at Karolinska Institutet published in the journal Translational Psychiatry reports.

Pregnant women with eating disorders should undergo extended pregnancy screenings considering their increased risk of complications. That is the conclusion from a study by researchers at Karolinska Institutet in Sweden published in the journal JAMA Psychiatry. The researchers were, for example, able to show that children to mothers with eating disorders had an increased risk of premature birth and being born with a small head circumference.

Twelve researchers at Karolinska Institutet qualify for the annual list of highly cited researchers compiled by Web of Science.

People with multiple sclerosis (MS) who also have depression are more likely to suffer debilitating symptoms early than people with MS who are not depressed, according to a study at Karolinska Institutet in Sweden that is published in the journal Neurology. The findings highlight the need for early recognition and treatment of depressive symptoms in patients with MS.

Refugees and other migrants who move to Sweden are initially less likely to be diagnosed with alcohol or drug addiction than the native population but over time their rates of substance abuse begin to mirror that of the Swedish born population. That is according to a new study by researchers at UCL in the U.K. and Karolinska Institutet in Sweden published in the journal PLOS Medicine.

The risk of suicide attempts and suicides among individuals with autism spectrum disorders is significantly higher than among the population in general. An especially high risk of suicidal behaviour is noted among women who in addition to autism also have ADHD. These are the findings of a population-based study from Karolinska Institutet in Sweden published in the journal Psychological Medicine.