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Infants who were given a taste of peanut, milk, wheat and egg from the age of three months had a lower risk of developing a food allergy at the age of three years than controls, reports a study by researchers from Karolinska Institutet in Sweden and the University of Oslo in Norway published in The Lancet.
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The causes of complex diseases can be identified by representing them in the form of mathematically produced networks. This method was used to find bacteria that drive atopic dermatitis, for example.
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Eleven researchers at five departments at Karolinska Institutet have received funding from Cancer- och Allergifonden (Cancer and Allergy Fund) for their point-of-care research projects on cancer and allergies. The researchers from Karolinska were allocated SEK 2.6 million. In total, the Fund distributed a total of five million SEK to Swedish cancer and allergy research.
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Many diseases caused by a dysregulated immune system, such as allergies, asthma and autoimmunity, can be traced back to events in the first few months after birth. To date, the mechanisms behind the development of the immune system have not been fully understood. Now, researchers at Karolinska Institutet show a connection between breast milk, beneficial gut bacteria and the development of the immune system. The study is published in Cell.
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In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient’s type of asthma. The study, which has been published in the American Journal of Respiratory and Critical Care Medicine, lays the foundation for a more personalized diagnosis and may result in improved treatment of severe asthma in the future.
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With the help of algorithms, researchers at Karolinska Institutet in Sweden have identified markers that can differentiate between irritant eczema and contact allergy, two skin reactions that look similar but require different treatment. Their findings, which are published in the journal Proceedings of the National Academy of Sciences (PNAS), support the further development of an alternative to today’s diagnostic patch tests.
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Cytokines are a type of proteins that are important to the signaling between cells in the body's immune system, for example in the case of an infection or injury. A new study in the Journal of Allergy and Clinical Immunology, by researchers researchers at Karolinska Institutet and Lund University, is now indicating that the cytokine interleukin(IL)-26 could be used as a biological marker (biomarker) for uncontrolled asthma in both adults and children.
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In contrast to what has been previously believed, development of blood stem cells to mast cells, a type of specialised immune cell, does not depend on a growth factor called stem cell factor. This has been demonstrated in a new collaborative study by researchers at Karolinska Institutet and Uppsala University, and published in the scientific journal Blood. The results could pave the way for new treatments for certain types of blood diseases.
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New research from Karolinska Institutet and the Stockholm South General Hospital shows that the alpha-gal carbohydrate, which is found in the tick intestine, can cause allergic reactions to red meat in bitten people.
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08-06-2022