News archive

Some children are born with hearing loss in only one ear. What to do then? The issue is more difficult than one might think.

One billion young people risk hearing loss in the future if they continue to listen to their headphones at too high a volume. To develop treatments, researchers need to solve the mysteries of the cochlea - well hidden in the inner ear, a pea-sized organ embedded in bone a few centimeters inside the outer ear.

The summer heat is here and with it questions about how we should handle high temperatures and what we should do to feel well in the heat. Cardiologist Petter Ljungman, associate professor at the Institute for Environmental Medicine and expert coordinator at the Centre for Health Crises, answers questions about health and heat.

Global Disaster Medicine - Health Needs and Responses is part of a consortium led by the Swedish Civil Contingencies Agency, called IPA Care, that aims to address the needs of countries on Western Balkan, along with Turkey, to strengthen their ability to prevent risks related to earthquakes and other health emergencies.

A groundbreaking study published in Nature Cardiovascular Research uncovers the crucial role of the AmotL2 protein in connecting mechanical forces to endothelial cell integrity and alignment. This discovery sheds light on junctional mechanotransduction and its implications for vascular disease, including abdominal aortic aneurysms (AAA). Importantly, the study reveals gender differences, with males showing a higher incidence of AAA.

An international team of researchers has developed a new method to deliver drugs into the inner ear, according to a new study in Science Translational Medicine. The discovery was possible by harnessing the natural flow of fluids in the brain and employing a little-understood backdoor into the cochlea. When combined to deliver a gene therapy that repairs inner ear hair cells, the researchers were able to restore hearing in deaf mice.

A new study in Nature by an international team including researchers at Karolinska Institutet has identified the first genetic variant associated with disease severity in multiple sclerosis. The finding opens the door to the development of treatments that fight disease progression – a great unmet need facing people with MS.

Congratulations to Samer Yammine at the Department of learning, informatics, management and ethics (LIME), who received the award "Male entrepreneurship educator of the year", an award included in The Triple E Awards!

The Rolf Zetterström prize for the best thesis in pediatrics 2022 goes to Stavroula Anastasopoulou who completed her dissertation at the Department of Women's and Children's Health last November. Her research contributes to improved treatment and lack of late effects for children and adolescents affected by acute lymphoblastic leukemia.

To bring Sweden’s presidency of the EU to a close, the government is arranging a European Life Science conference to be held at Karolinska Institutet’s Aula Medica on 26–27 June. The theme of the conference is precision medicine, and KI – along with Karolinska University Hospital – has helped to draw up the programme.

Assistant Professor Maurice Michel has received the Eppendorf Award for Young European Investigators 2023 for his research on artificial functions of DNA repair enzymes.

Five researchers at Karolinska Institutet are awarded 30 million Swedish kronor from the Swedish Research Council (VR) to establish a so-called centre of excellence for further development of cell-based cancer treatments. The funds will be distributed over five years, with the potential for another five years of funding after evaluation.

Researchers at Karolinska Institutet have identified a group of nerve cells in the mouse brain that are involved in creating negative emotional states and chronic stress. The neurons, which have been mapped with a combination of advanced techniques, also have receptors for oestrogen, which could explain why women as a group are more sensitive to stress than men. The study is published in Nature Neuroscience.

Federico Iovino and his lab members have been awarded with a grant from the ItsME Foundation to enable their research on the prevention of neuronal damage caused by bacterial infections. The ItsME Foundation was founded in 2019 by Jur Deitmers and has its base in The Netherlands, with the goal to fight Meningitis and Encephalitis.

From June 26 to August 11, KI Housing will have limited staff on duty which will have an impact on our service. During this period, urgent questions and maintenance issues will be prioritized and it may take some time before we get back to you.

A team of researchers at Karolinska Institutet and Yale School of Medicine wanted to know what happens to mosaic skin upon injury. Do simple wounds or surgery enhance the skin cancer risk by expanding mutated cells even more as generally believed? The surprising answer is no, according to newly published study in Nature.

In the middle of May, around 30 students and three teachers from The School of Health Sciences, Western University, Ontario, Canada, visited the study programmes in health care sciences at NVS. This is part of a collaboration that started on a smaller scale in 2018, and after a short break during the pandemic is back on track since last year.

In June 2023 representatives from Karolinska Institutet visited Washington DC and New York City in the US. Connected to several collaborations important to KI and with strategic plans to increase alumni activity in the US, the visit included a SIREUS event hosted at the House of Sweden in DC, as well as two planned alumni events in DC and New York, along with valuable alumni visits to Rockefeller University and Memorial Sloan Kettering Cancer Center.

Almost a hundred experts from 27 countries took part in a hackathon on June 17–18 to identify diseases in 14 patients lacking diagnoses. “Four of them have now received an answer and we’re confident that more are to come,” says professor and consultant Ann Nordgren, who was one of the organizers of the event.

A watercolour painting, anatomical artwork or a whole house dedicated to the body. When scientists turn to art, science takes on new forms.

SFO-V regularly announces calls for partial financing of sabbaticals within health care sciences. This past spring, Susan Guidetti, professor at the Division of Occupational Therapy and Eric Asaba, docent and senior lecturer at the Division of Occupational Therapy were granted funding for sabbaticals in Ugandan and USA, respectively.

In a nationwide Swedish study of more than 85,000 patients with biopsy-confirmed inflammatory bowel disease (IBD), researchers from Karolinska Institutet and Örebro University (Sweden) observed that IBD patients had an increased risk of stroke, especially of ischaemic events, compared to the general population. The results are published in Neurology.

Many men in northern Europe over the age of 60 suffer from the so-called Viking disease, which means that the fingers lock in a bent position. Now researchers at Karolinska Institutet, together with colleagues, have used data from over 7,000 affected individuals to look for genetic risk factors for the disease. The findings, which have been published in Molecular Biology and Evolution, show that three of the strongest risk factors are inherited from Neanderthals.

PROMINENT Project, which was officially launched today, will Enhance Diagnosis and Treatment of Neurodegenerative Diseases, Improving Patients' Lives Across Europe.

The European Health Conference and Exhibition HIMSS (Healthcare Information and Management Systems Society) 23 was held on the 7-9 June, 2023 in Lisbon.

Assistant professor Marcus Buggert at Karolinska Institutet is awarded Anders Jahre's prize for young researchers 2023 and 400.000 NOK.

A new DNA-based COVID-19 vaccine is now being tested for the first time on healthy volunteers at Karolinska University Hospital. The vaccine has been developed at Karolinska Institutet and target multiple parts of the virus, making it less vulnerable to mutated strains and potentially effective against new variants.

Researchers at Karolinska Institutet have created a new method of studying the smallest bioparticles in the body. The study, which is published in Nature Biotechnology, has considerable scientific potential, such as in the development of more effective vaccines.

The project was presented at the conference in Munich in May, 2023.

Solving the logic of life. This may seem like an overwhelming task. But for Professor Rickard Sandberg, this is the objective.

The Encephalitis Society is a worldwide international charity with the mission of building better futures by driving research, accelerating awareness, and saving lives. In the latest issue of their newsletter which has been running since 2003, the society has chosen to highlight the research performed in Federico Iovino's group.

Creative ideas were born when the NeurotechEU alliance arranged a hackathon at Karolinska Institutet. “Activities like this highlight the value of having people from other disciplines and countries – and at different stages of their careers – engage in cross-border innovative processes with each other,” says KI president Annika Östman Wernerson.

This is a short report from the project team working on the implementation of KI RIMS. The posts are aimed at those who are interested in the work of adapting the product Elements from Symplectic to KI's requirements and conditions and want to follow the development process.

Maria Karvouni from the Center for Hematology and Regenerative Medicine (HERM) at the Department of Medicine, Huddinge (MedH) is defending her thesis: "Cellular and personalized therapies in Multiple Myeloma with special emphasis on retargeted NK cells" 16 June 2023. Main supervisor is Evren Alici (MedH).

The project Systems support for research information continues the implementation of KI RIMS and will during the summer focus on further technical development and designing user support.

A new study from the Kristina Broliden research group at the Department of Medicine in Solna, shows that women with a healthy bacterial flora in the vagina can simultaneously have disease-linked bacteria attached to the ectocervical mucosa. The study has recently been published in the journal Microbiome.

KI-Region Stockholm is the ALF region that best meets the quality criteria in the National Board of Health and Welfare’s evaluation of academic healthcare (USV). The results of the evaluation were compiled into a report published on 31 May. Research is the Stockholm region’s strongest area, but the report also comments positively on its innovation, pedagogics education and interaction with patients and their families.

Nasopharyngeal carcinoma (NPC) is a type of cancer that occurs in the nasopharynx, which is located behind the nose and above the back of the throat. NPC has a geographically skewed distribution worldwide, with high incidence rates in East and Southeast Asia. NPC is difficult to detect early, and treatment usually involves radiation therapy, chemotherapy or a combination of the two.

Forte is allocating SEK 160 million to research on the health and well-being of older people. The funds are divided into three programme grants and 19 project grants and the research will begin in 2023 and continue until 2029. Two researchers at the Aging Research Center (ARC), Karolinska Institutet, have been granted funding for their important research within the ageing research area.

Older autistic adults have a significantly higher risk of injury, especially self-inflicted, and physical conditions such as type 2 diabetes, anaemia, heart failure and COPD. This is according to a large-scale registry study from Karolinska Institutet published in The Lancet Healthy Longevity.

Our skin contains specialised long-lived killer cells that protect against intruders. Researchers at Karolinska Institutet and the University of Copenhagen have now identified how these cells are formed, and shown that high levels of memory killer cells in cancer tissue correlate with a better survival rate in people with melanoma. The study is published in the journal Immunity.

In a new study, researchers at Karolinska Institutet show that recombinant spider silk protein hydrogels have many attractive features. They allow encapsulation of cells and bioactive molecules simply by incubation at 37°C. They are transparent, which allows monitoring of encapsulated cells, and the fibrillar network mimics that of the extracellular matrix. The mechanical properties of these hydrogels match those of different tissues, and the gels can be used for continuous drug release.

Hi there Jing Wu! You are about to defend your thesis entitled “Ambient Air Pollution and Transportation Noise: How They Affect Mental Health in Older Adults”. Could you tell us a little bit more about it?

Jenny Mjösberg at the Department of Medicine in Huddinge at Karolinska Institutet, receives the 2023 Eric K. Fernström Prize for young, promising and successful researchers, for her outstanding research on the role of innate lymphoid cells in various diseases.

In the largest survey to date, researchers at Karolinska Institutet have studied how diseases of the aortic valve affect prognosis in patients with various types of heart failure. The study was published in the European Journal of Heart Failure. Shared first authors are sisters Angiza and Bahira Shahim, who also presented the results of the study at the Heart Failure International Conference in Prague.

Older people with ischemic heart disease have an increased long-term risk of dementia and accelerated cognitive decline. A recent study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, suggests that the heart, the brain, and cognitive function are connected in the ageing process and that appropriate prevention and treatment of ischemic heart disease in older people might reduce the burden of dementia.

Hanna Karlsson and Sara Widén are the first ever recipients of KI’s new Sustainability Award, which they have earned in recognition of their efforts to support the KI faculty on issues of sustainability.

This is a short report from the project team working on the implementation of KI RIMS. The posts are aimed at those who are interested in the work of adapting the product Elements from Symplectic to KI's requirements and conditions and want to follow the development process.

The Swedish Research Council for Health, Working Life and Welfare (Forte) is allocating over SEK 91 million to KI research on elderly wellbeing and future working life. One of the researchers, who is to receive SEK 24 million, is Associate Professor Carin Håkansta at Karolinska Institutet and Karlstad University, who will be examining how the working environment is affected when some managerial tasks are taken over by algorithms.

Hi Nathalie Frisendahl, PhD student at the Division of Physiotherapy. On June 16 you will defend your thesis ”Injurious falls in older adults: early identification of individuals at risk of falls—from observational studies to implementation”, what is the main focus of the thesis?