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A new study published in the research journal PLOS Pathogens, shows for the first time the essential role of the molecule SOCS3 in the control of Tuberculosis. This could have impact on the future development of a vaccine.

Scientists at Karolinska Institutet have identified the neuronal circuits in the spinal cord of mice that control the ability to produce the alternating movements of the legs during walking. The study, published in the journal Nature, demonstrates that two genetically-defined groups of nerve cells are in control of limb alternation at different speeds of locomotion, and thus that the animals' gait is disturbed when these cell populations are missing.