News archive

From September 20, the Supply Center on floor 2 has new opening hours.

Cardiogenic growth factors play important roles in heart development and in a new study published in the scientific paper Nature Communications from researchers at Karolinska Institutet shows how stem cell therapeutics and mRNA technology are beginning to converge offering major improvements in vascularization, survival, expansion, differentiation, and ultimately the function of human stem cell grafts.

CLINICUM is part of the region-wide initiative that aims to strengthen the quality of clinical and translational research. In its entirety, CLINICUM consists of a central function and seven nodes which represent the care provider organizations in Region Stockholm and SLSO. The nodes' activities aim to offer scientific advice and to provide methodological support and guidance in the planning and execution of research projects.

Starting from week 34, there will be two lunch training sessions per week for all employees at Biomedicum. The training will be diverse, and everyone can participate since the exercises will be easy to perform at the level that suits each individual.

Stressed at the office or in the lab? Stiff shoulders? Need focus? Join us for lunch yoga sessions in Biomedicum. Everybody is welcome - no experience needed!

A new study published in Cell Metabolism by the research group of Professor Nils-Göran Larsson, at the Department of Medical Biochemistry and Biophysics, Karolinska Institutet, shows that so-called supercomplexes have no major role in cellular energy production and that altered levels therefore are unlikely to affect physiology and disease.

Biomedicum’s own choir, Biomusicum, now welcomes new members. The choir is open for all staff and students at Biomedicum and both beginners and experienced singers are welcome. No previous experience required. If you have always wondered about singing in a choir, but have never taken the step, then this is your opportunity!

During the dates 11 -22 September 2023, Biomedicum fire safety supervisor Jennie Eldh Bastman will carry out fire safety inspections in Biomedicum. Safety representatives have been offered to accompany and may also be present.

The deficiency of functional insulin-producing cells is a common feature of type 1 and late-stage type 2 diabetes. Previous studies have suggested that mammals have very limited capacity for regeneration of insulin-producing cells, but researchers at Karolinska Institutet have found how zebrafish can form new cells and thereby provide clues to possible future possibilities in diabetes. The study is published in the scientific journal Science Advances.

Susanne Nylén at the Department of Microbiology, Tumor and Cell Biology at KI, is leading a project that has been awarded a four-year grant from the Dutch foundation Dioraphte for research on the pathogenesis of post-kala-azar dermal leishmaniasis (PKDL) and leprosy. The total amount awarded is 850 000 euros.

Researchers from Karolinska Institutet have discovered a new molecular mechanism by which cancer cells safeguard themselves from oncogene-induced replication stress and propose a strategy to deactivate this protective mechanism. The study is published in the scientific journal Molecular Cell.

The conference website including the preliminary program is now online! Abstracts can be submitted at the beginning of December via the website.

KI researcher Yihai Cao and his research group at the Department of Microbiology, Tumor and Cell Biology, have defined a new biomarker for predicting drug resistance of antiangiogenic therapy for the treatment of various cancers. The study is published in PNAS.

We are excited to announce that we are in the process of acquiring a new sorter for our Flow Cytometry Core Facility at Biomedicum. This acquisition aims to expand our sorting capacity, allowing us to better accommodate the needs of our researchers.

We are thrilled to announce the latest additions to our core facility. We have recently acquired two Sony ID7000 spectral analyzers, Alice and Howard. These analyzers are equipped with advanced features, including five lasers and an array of 147 detectors, enabling high-resolution spectral analysis.

Kristina Ösund will start her position as Head of Administration at the Department of Physiology and Pharmacology on 14 August.

Supply Center Biomedicum has existed since moving in in 2018. The idea was that consumables could be easily and efficiently ordered online via the e-commerce module in UBW. However, it didn't quite turn out that way and the idea of ​​setting up a physical store has been lurking ever since.

The 5D Heart Patch Project, led by Prof Kenneth Chien, has identified human ventricular progenitor (HVP) cells that can create self-assembling heart grafts in vivo. The research has the potential to offer hope to millions of people suffering from heart failure.

Jelena Misic, PhD in Nils-Göran Larsson Group at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet, has been selected to participate in the Lindau Nobel Laureate Meetings in June 2023. Jelena studies different aspects of mitochondrial gene expression in mammals.

In a recently published article published in Nature Reviews Drug Discovery, Professor Yihai Cao’s research group at the Department of Microbiology, Tumor and Cell Biology, charts the information about drug development for the treatment of a number of human diseases by targeting new blood vessel formation.

The group of expert coordinators at the Centre for Health Crises keeps growing. The expert coordinators manage the work that is done within their field of expertise. The latest area of expertise to be added to the Centre is laboratory and diagnostic preparedness, with Jessica Alm as expert coordinator.

The FM newsletter is sent to all employees working in Biomedicum about twice a semester and includes news from the Facility Management. 

In order to make the FM service even more efficient we have created a new team, Team Laboratory Service. Johanna Steen is head of the new team which is divided in two groups: Laboratory safety and Dishwashing and sterilization facility.

Meet our new co-worker Helena Hatziantoniou, responsible for the Supply Center in Biomedicum.

The Svedberg prize 2023 is awarded to Simon Elsässer, Department of Medical Biochemistry and Biophysics at Karolinska Institutet, for his contributions to our understanding of epigenetic gene regulation.

A new study published in Nature reports that a technology known as spatial omics can be used to map simultaneously how genes are switched on and off and how they are expressed in different areas of tissues and organs. This improved technology, developed by researchers at Yale University and Karolinska Institutet, could shed light on the development of tissues, as well as on certain diseases and how to treat them.

The proceeds from recyclable cans & bottles in Biomedicum are donated to Läkare Utan Gränser and during 2022 we reached 10 107 SEK! Thank you all for your contribution!

The first detailed description of the microbiota and immune cells among asymptomatic Helicobacter pylori-infected individuals has been published by researchers at Karolinska Institutet. The results of the study will be instrumental to understand the complex microbiome and immunity network and provide new insights for asymptomatic Helicobacter pylori infection.

Five separate evacuation drills were carried out between 12-15 December 2022. The evacuation drills were documented by the Facility Management team and the reception in Biomedicum to better analyse the organisation’s current status, deficiency and needs.

An internal investigation has been carried out following the incident that occurred on 17 November 2022, when the evacuation alarm with spoken message was activated due to a smoke-filled microwave on floor 5, in Biomedicum.

Biomedicum’s own choir, Biomusicum, now welcomes new members. The choir is open for all staff and students at Biomedicum and both beginners and experienced singers are welcome. No previous experience required. If you have always wondered about singing in a choir, but have never taken the step, then this is your opportunity!

Researchers at Karolinska Institutet uncover the function of the release factor mtRF1 in the final steps of mitochondrial protein synthesis. The study, published in Nature Communications, reveals new insights into a fundamental process in mitochondria.

Researchers at Karolinska Institutet and Stockholm University have developed a new technology allowing simultaneous probing of several different histone marks in one individual cell and in thousands of cells at the same time. This new method allows to investigate in much greater detail how cells in the mouse brain acquire unique properties and specialize. The study is published in the journal Nature Biotechnology.

Critical illness myopathy (CIM) is a common complication affecting ventilator-treated intensive care patients, which can lead to increased mortality/morbidity, prolonged hospital care, impaired patient quality of life, and increased healthcare costs. reported molecular pathogenesis of CIM during prolonged ICU stay, and potential diagnostic biomarkers and therapeutic targets. The study was recently published in Journal of Cachexia, Sarcopenia and Muscle.

Meet Andreas Adolfsson, Operations technician at FM, operating and working in the Facility Management workshop (FM verkstad), located on floor 2, room A0262) in Biomedicum.

This is the first employee survey that has been performed since the establishment of Facility Management (FM), in 2018. The survey allowed all employees in Biomedicum to answer 18 questions about FM's service and support. What works well and what can be improved. 

Parking stickers from Aimopark for staff are now available at the reception in Biomedicum.

The restaurant business is closed from 23/12 to 31/12

The widely used gene scissor (CRISPR/Cas) can modify the genetic content in cells to study the molecular roles of genes and has gained great clinical relevance in gene therapy to treat genetic diseases. A new study performed by Claudia Kutter’s research group at the Department of Microbiology, Cell, and Tumor Biology at Karolinska Institutet, found that the gene scissor leads to unexpected genomic changes.

Researchers at Karolinska Institutet Qiaolin Deng and Georgios Sotiriou receive the KI Research Incubator (KIRI) Fellow postdoc grant 2022. The KIRI Fellow grant finances a postdoc for a collaborative interdisciplinary project. The awarded project aims to expand the use of tailored nanoparticles as drug carriers to deliver them to a dysfunctional placenta providing treatments to improve the child’s metabolic health.

Researchers at Karolinska Institutet have in a new study used cellular reprogramming to create human three-dimensional brain models and infected these models with SARS-CoV-2. In infected models, the brain immune cells excessively eliminated synapses and acquired a gene expression pattern mimicking what has been observed in neurodegenerative disorders. The findings could help to identify new treatments against persistent cognitive symptoms after a Covid-19 infection.

The Property and Facilities Office at Karolinska Institutet will no longer offer AV support for the meeting rooms in Biomedicum that we book via outlook. Thus, the routine needs to change.

We have a new framework agreement regarding fruit baskets. Our new supplier is Monica Askebäcks Frukt AB (FruitHero) from 2022-09-02.

Professor Yihai Cao, Department of Microbiology, Tumor and Cell biology, is the corresponding author of a study recently published in PNAS, explaining how brown adipose tissue (BAT) can be increased in the adult human body.

The Supply Center in Biomedicum is up and running with more suppliers and products. Orders can be placed in Agresso.

As of August 2022 Christina Johansson is new head of administration at the Department of Physiology and Pharmacology (FyFa). Christina has worked in various roles and departments at KI since 2015, most recently as head of administration at the Unit for Teaching and Learning (UoL).

In a recently published article in the journal Trends in Microbiology, author Alberto J. Martin-Rodriguez, Senior Research Specialist at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet, explains how he found that distinct bacterial strains selectively use respiration for surface colonization.

In a new publication in Nature communications, Martin Rottenberg and Ruining Liu, professor and PhD student at the Department of Microbiology, Tumor and Cellbiology, explains how T cell protection against Tuberculosis is controlled by their oxygen responses.

New research from Yihai Cao research group at the Department of Microbiology, Tumor and Cellbiology, MTC, shows that the so-called brown fat in the human body seems to be able to prevent cancer tumors from growing. The result is published by Nature and has been widely disseminated in the media lately.

In a recently published review article in Cell, researchers Jon Lundberg and Eddie Weitzberg at the Department of Physiology and Pharmacology at Karolinska Institutet summarize research in nitric oxide (NO) with a focus on what is happening right now.