News archive

On this page you can search for older news. Choose a topic, type of news or enter your own keyword to filter out news.

View expanded
View compact
Drugs known as GLP-1 analogues have become increasingly popular to treat diabetes and obesity, but there have been concerns that they might increase the risk of thyroid cancer. Now an extensive Scandinavian study led by researchers at Karolinska Institutet has found no evidence of such a link. The study is published in The BMJ.
News
The guidelines for weight gain during pregnancy in obese women have long been questioned. New research from Karolinska Institutet supports the idea of lowering or removing the current recommendation of a weight gain of at least 5 kg. The results are published in The Lancet.
News
The project "A Healthy School Start" is a family support program developed by the research group Community Nutrition and Physical Activity at the Department of Global Public Health, to offer an adapted approach for student health and teachers to provide support to families with children on healthy lifestyles. The program has been positively received by politicians in Region Stockholm, who have now allocated funds in the budget for further dissemination.
News
New research from Karolinska Institutet shows how oestrogen protects against MASLD, a fatty liver disease that has increased dramatically during the current obesity epidemic. The study, published in Molecular Systems Biology, shows how a new drug under development could become a future treatment for fatty liver disease and liver cancer.
News
The European Research Council (ERC) awards a Starting Grant to promising young investigators in a variety of research fields, to kick off their careers. Alessandro Furlan, Assistant Professor at the Department of Neuroscience, who investigates how the brain and body work together to regulate critical physiological processes, is one of the early-stage scientists to be awarded this five-year grant.
News
Researchers at Karolinska Institutet have developed a method to study liver function and disease without requiring invasive procedures. After transplanting liver cells into the eye of mice, the cornea can be used as a window into the body to monitor liver health over time. The study is published in the journal Nature Communications.
News
Young people who have had surgery for obesity do not improve their mental health despite significant and permanent weight loss. However, bariatric surgery increases the risk of early alcohol problems. This is according to the largest long-term study of young people who have undergone bariatric surgery, conducted at Lund University and Karolinska Institutet, among others.
News
The abundance of unhealthy food in society means that obesity doctor and researcher Ylva Trolle Lagerros is working against certain headwinds. But the arrival of new medications have made her job more enjoyable. In parallel, she has developed apps that provide patients with support.
News
There is a well-known relationship between good physical fitness at a young age and a lower risk of cardiovascular disease later in life. However, when researchers adjusted for familial factors by means of sibling analysis, they found a weaker association, although the link between high body mass index (BMI) and cardiovascular disease remained strong. The study, which was conducted by researchers from Karolinska Institutet and other universities, is published in JAMA Network Open.
News
A researcher at the Department of Biosciences and Nutrition, Karolinska Institutet, has received SEK 4.97 million in research grants from FORTE for a project on “A mHealth intervention to promote healthy lifestyle behaviours from the start of life: The Health4Life trial”.
News
The early treatment of obesity in children is effective in both the short and long term, researchers from Karolinska Institutet report in a study published in International Journal of Obesity.
News
Sons of women with polycystic ovary syndrome (PCOS) have a twofold increased risk to develop obesity, according to a study published in Cell Reports Medicine. According to the researchers from Karolinska Institutet the findings highlight a previously unknown risk of passing PCOS-related health problems across generations through the male side of a family

News
The risk of developing cardiovascular disease is lower in people with obesity who have a genetic predisposition for high BMI than people with obesity influenced mainly by environmental factors such as lifestyle, researchers from Karolinska Institutet report in eClinicalMedicine.
News
With the help of a multi-language smartphone app, parents in Sweden were able to give their young children better dietary habits and less screen time, a study by researchers from Karolinska Institutet published in the International Journal of Behavioral Nutrition and Physical Activity reports.
News
Child obesity is linked to increased risk of developing diabetes in adulthood, both autoimmune forms of diabetes and different forms of type 2 diabetes, a new study published in Diabetologia reports. The risk of developing the most insulin-resistant form of diabetes is, for example, three times as high in children with obesity.
News
Physical activity at the right time of the day seems able to increase fat metabolism, at least in mice. A new study from Karolinska Institutet in Sweden and the University of Copenhagen in Denmark shows that mice that did exercise in an early active phase, which corresponds to morning exercise in humans, increased their metabolism more than mice that did exercise at a time when they usually rest. The results are published in the journal PNAS.
News
There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases. A study led by researchers from Karolinska Institutet has now identified a drug candidate for the treatment of fatty liver. The preclinical study, published in the Journal of Hepatology, indicates that an antibody that blocks the protein VEGF-B presents a possible therapeutic option for fatty liver disease.
News
Losing too much weight when infected with COVID-19 has been linked to worse outcomes. Now, researchers at Karolinska Institutet have discovered that SARS-CoV-2 infection fuels blood vessel formation in fat tissues, thus revving up the body’s thermogenic metabolism. Blocking this process by using an existing drug curbed weight loss in mice and hamsters that were infected with the virus, according to the study published in the journal Nature Metabolism.
News
Jenny Vinglid has been General Secretary of HOBS, a Swedish patient association for people living with overweight and obesity, since 2013. According to her, people with obesity are discriminated in the healthcare system.
News
A mobile app that shows a child's weight development in real-time for children with obesity provides greater weight loss compared to conventional care. The fact that both families and healthcare professionals can follow the same data facilitates individualised extra support when needed. This is shown by a study from Karolinska Institutet published in the International Journal of Obesity.
News
Congratulations to researchers at the Department of Biosciences and Nutrition, Karolinska Institutet, who have received grants from "Henning och Johan Throne-Holst stiftelse" 2022.
News
In a new study published in Nature Metabolism, KI researchers show how disturbances in the energy metabolism in human fat cells, can lead to the development of inflammation and insulin resistance.
News
It is well known that obesity affects the body's insulin production and over time risks leading to type 2 diabetes and several other metabolic diseases. Now researchers at Karolinska Institutet in Sweden have found further explanation for why fat cells cause metabolic morbidity. The study, published in Nature Medicine, may have an impact on the treatment of comorbidity in obesity with already available drugs.
News
It is well known that fat cells can influence our sensitivity to insulin. Now, researchers at Karolinska Institutet in Sweden have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these, called AdipoPLIN, that responds to insulin. The findings may be relevant for future treatments of metabolic diseases such as Type 2 diabetes.
News
Obesity increases the risk of developing cancers of the digestive system and it is the person’s fat mass, rather than size, that is the main obesity-related risk factor for these cancer types, according to a new study published in the journal PLOS Medicine by researchers at the University of Cambridge and Karolinska Institutet.
News
Children and young people whose mothers had a BMI greater than 30 during early pregnancy are at an increased risk of fatty liver disease. This is shown in a register-based study from Karolinska Institutet and Harvard University published in the journal Journal of Hepatology. As obesity rates increase also in women at a child-bearing age, more and more young people are at risk of developing fatty liver disease, the researchers say.
News
Researchers at the Karolinska Institutet, University of Oxford and University of Copenhagen have shown that elevated levels of lipids known as ceramides can be associated with a ten-fold higher risk of death from cardiovascular disease. Treatment with liraglutide could keep the ceramide levels in check, compared with placebo. The results have been published in the Journal of the American College of Cardiology.
News
Non-alcoholic fatty liver disease, NAFLD, is associated with several health risks. According to a new registry study led by researchers at Karolinska Institutet in Sweden, NAFLD is linked to a 17-fold increased risk of liver cancer. The findings, published in Hepatology, underscore the need for improved follow-up of NAFLD patients with the goal of reducing the risk of cancer.
News
Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet shows that it is possible to eliminate the deleterious effects of a high-fat diet by lowering the levels of apolipoprotein CIII (apoCIII), a key regulator of lipid metabolism. The study is published in the journal Science Advances.
News
As life expectancies rise, so does the risk of dementia. Researchers at Karolinska Institutet have now studied how an active, non-smoking lifestyle can influence this correlation. The results, which are published in PLOS Medicine, suggest that good cardiovascular health gradually decreases the risk of dementia.
News
Knowledge of how human fat tissue is affected by age has long been defined by numerous mouse-based studies. Researchers at Karolinska Institutet in Sweden have now, for the first time, been able to conduct a prospective study on humans that provides novel insights into how our fat cells reduce lipid metabolism with age. The study is published in the journal Cell Metabolism.
News
Physical exercise can act prophylactically for people with the metabolic syndrome and protect them against cardiovascular diseases, a new study from the Swedish School of Sport and Health Sciences, GIH, and Karolinska Institutet published in the European Journal of Preventive Cardiology reports. Even light physical exercise has been shown to have good prophylactic effects, for both women and men.
News
Two new studies from Karolinska Institutet in Sweden underscore health risks associated with childhood obesity. Children with obesity have a three times higher risk of mortality in early adulthood compared with children in the general population and are more likely to suffer from anxiety and depression. The findings, published in PLOS Medicine and BMC Medicine, highlight the need to identify specific risk factors for children with obesity and find preventative tools, say the researchers.
News
Researchers at Karolinska Institutet in Sweden have identified a molecular pathway that when silenced could restore the normal function of immune cells in people with fatty liver disease. The findings could lead to new strategies for treating the condition, which is a major health risk for people with obesity. The study is published in the scientific journal Science Translational Medicine.
News
Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. The researchers also show how glutamine levels can alter gene expression in several different cell types. However, more research is needed before glutamine supplementation may be recommended as a treatment for obesity. The study is published in the journal Cell Metabolism.
News
Women who have C-sections are no more likely to have children who develop obesity than women who give birth naturally, according to a large study by researchers at Karolinska Institutet in Sweden published in the journal PLOS Medicine. The findings contradict several smaller studies that did find an association between C-section deliveries and offspring obesity but did not consider the numerous maternal and prenatal factors that the researchers did in this study.
News
Children born to women who underwent gastric bypass surgery before becoming pregnant had a lower risk of major birth defects than children born to women who had severe obesity at the start of their pregnancy. That’s according to a matched cohort study by researchers at Karolinska Institutet and Örebro University published in the scientific journal JAMA. The findings indicate that weight-loss and improved blood sugar control could reduce the risk of major birth defects.
News
Many people struggle to keep their weight in check as they get older. Now new research at Karolinska Institutet has uncovered why that is: Lipid turnover in the fat tissue decreases during ageing and makes it easier to gain weight, even if we don’t eat more or exercise less than before. The study is published in the journal Nature Medicine.
News
A new study from Karolinska Institutet shows that the same mechanisms behind the beneficial effects of exercise training on the brain also help to counteract fat and to strengthen the immune system. The results, which are published in the journal Cell Metabolism, can ultimately give rise to new obesity and diabetes drugs.
News
KI webbförvaltning
09-06-2023