News archive

Opinions and facts sometimes clash on the question of the causes of autism - genetics or environment? Kristiina Tammimies, associate professor of medical genetics at Karolinska Institutet, has the answer: "Autism is mainly due to the genes we are born with, but environmental factors play a role," she says.

Researchers at Karolinska Institutet have uncovered new insights into the mechanisms underlying autism spectrum disorder (ASD). The study, recently published in Cell Reports, explores how changes in dopamine (DA) neurotransmission in the brain contribute to the behavioural symptoms of autism.

Autism affects 2-3% of U.S. children and there is no cure. Both genetic and environmental factors contribute to its etiology. Researchers at the Karolinska Institutet and the Icahn School of Medicine at Mount Sinai have received an NIH grant of 2.5 million USD for the 5-year project "Autism in Preterm Birth".

A new machine learning model can predict autism in young children from relatively limited information. This is shown in a new study from Karolinska Institutet published in JAMA Network Open. The model can facilitate early detection of autism, which is important to provide the right support.

Older autistic adults have a significantly higher risk of injury, especially self-inflicted, and physical conditions such as type 2 diabetes, anaemia, heart failure and COPD. This is according to a large-scale registry study from Karolinska Institutet published in The Lancet Healthy Longevity.

Autistic young men and women are more affected by psychiatric conditions and have an increased risk of being hospitalized as a result of their mental illness compared with non-autistic people. Autistic women are particularly vulnerable. This is shown by researchers from Karolinska Institutet in a study published in JAMA Psychiatry.

Infections in pregnant women have been linked to an increased risk of neurodevelopmental conditions, such as autism, in the child later in life. But it does not seem to be the infections themselves that cause autism, researchers from Karolinska Institutet show in a study published in The Lancet Psychiatry.

A doctoral thesis at Karolinska Institutet has investigated whether Acceptance Commitment Therapy (ACT) can be used for individuals with Autism Spectrum Disorder. The results show that the treatment can be carried out in both a school environment and in psychiatric outpatient care and can have an effect on, among other things, perceived stress.

Researchers at Karolinska Institutet have investigated the association between certain immune markers in neonates and the risk of later developing autism spectrum disorder (ASD). They found that mid-levels of a classical marker of inflammation, C-reactive protein, were associated with the lowest risk for ASD – whereas too much or not enough were linked to increased risk. The study is published in the scientific journal Biological Psychiatry.

People with autism spectrum disorder have lower levels of a protein that regulates the amount of serotonin in the brain, a paper from Karolinska Institutet in Sweden published in the journal Molecular Psychiatry reports. For their study, the researchers used a molecular brain imaging technique to compare people with and without autism; their results offer hope of finding a drug that can alleviate the symptoms.

Two recent studies were unable to rule out that H1N1 (“swine flu”) vaccination (“Pandemrix”) and seasonal influenza vaccination given to pregnant women might be associated with autism spectrum disorder in the offspring. Now, a large study by researchers at Karolinska Institutet in Sweden, published in the journal Annals of Internal Medicine, refutes any such association.

A new registry study, dismiss the long-debated association between celiac disease – gluten intolerance – and increased risk of autism spectrum disorders. The study was led from Karolinska Institutet and is now published in JAMA Psychiatry.