Participants sought for studies Can we accurately estimate the number of nerve-muscle connections in your legs?

In this study we are looking for participants to test a new method to estimate nerve-muscle connections in the lower leg using safe electrical stimulation.

Genre image of 3d rendered image shown neuromuscular junction, where nerve end splits into several neural end plates on different muscle cells.
Neuromuscular Junction - 3d rendered image showing neuromuscular junction, where nerve end splits into several neural end plates on different muscle cells. Photo: Getty Images

How does the study work?

You will be asked to visit Karolinska University Hospital in Huddinge on 2 separate occasions within a week. Each session will last approximately 1.5 to 2 hours.

Sessions will involve brief electrical stimulations to a peripheral nerve in the legs. This technique is safe and has been reliably established for use in research. We will use sensors on your skin to measure the small electrical signals of your muscles.

The study aims to test the robustness of a novel method to estimate the number of nerve-muscle connections in the calf muscles.

Who can participate?

You may be eligible if you:

  • Are 18-50 years old and free of pain
  • Are not pregnant
  • Have not been diagnosed with a neurological disorder
  • Do not have a pacemaker fitted

Reimbursement

Participants will be given a SEK 300 gift card.

Contact

If you would like to receive more information and potentially participate, please contact:

Profile image

Ricardo Mesquita

Postdoctoral Researcher
Department of Laboratory Medicine

The project has been approved by Etikprövningsmyndigheten (2026-00753-01).

Processing of personal data

Your personal data is processed for the purposes of this study in accordance with GDPR (General Data Protection Regulation). The legal entity responsible for processing of your personal data is Karolinska Institutet. The Data Protection Officer can be reached at dataskyddsombud@ki.se. The data will be analyzed on a group level, handled confidentially and it will be stored in a secure database at Karolinska Institutet. You can terminate your participation in the study at any time.