Thesis on hyper- and hypothyroidism

Most people with thyroid disease are helped by established treatments, but not all. In his thesis, Fredric Hedberg studied treatments that are used when standard treatment is not enough for hyper- and hypothyroidism; iodine solution (Lugol) and combination treatment with the thyroid hormone T3. The results contribute to increased knowledge about these treatments.

“In the treatment of hyper- and hypothyroidism, we can in most cases rely on well-established therapies. However, in our clinical practice we sometimes encounter patients for whom standard treatment is not sufficient”, says Fredric Hedberg, PhD student at the Experimental and Clinical Neuroendocrinology research group, Department of Molecular Medicine and Surgery, Karolinska Institutet and Associate Senior Physician, ME Endocrinology, Karolinska University Hospital.
“In the thesis, we have therefore studied non-standard treatments for thyroid disease, with a focus on iodine solution (Lugol's solution) for hyperthyroidism and additional treatment with T3 hormone (liothyronine) to T4 treatment (levothyroxine) for hypothyroidism”, he continues.
Please visit the Swedish site for more information on the thesis.
Dissertation
The doctoral thesis has been supervised by Henrik Falhammar. The dissertation seminar will be held on April 17th, 2026 at 09:00, Skandiasalen, Karolinska University Hospital.
Thesis
Hedberg, Fredric (2026). Treatment of hyper- and hypothyroidism : Lugol’s iodine and liothyronine. Karolinska Institutet. Thesis. https://doi.org/10.69622/30665984.v1
