Lectures and seminars OnkPat Friday Seminar: Crossing the valley of death - from retrospective research and prospective clinical trials to clinical routine

Host: Kasper Karlsson, Department of Oncology-Pathology

About Johan Lindberg

Principal Researcher at the Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, with a focus on biomarker discovery and cancer genomics assay development. Responsbile for genomic profiling in randomised clinical trials and has led implementation of cancer genomics assays for clinical routine at Karolinska Hospital.

Publications

Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer. Reply.
Martling A, Myrberg IH, Lindberg J
N Engl J Med 2025 Nov;393(21):2173

Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial.
De Laere B, Crippa A, Discacciati A, Larsson B, Persson M, Johansson S, D'hondt S, Bergström R, Chellappa V, Mayrhofer M, Banijamali M, Kotsalaynen A, Schelstraete C, Vanwelkenhuyzen JP, Hjälm-Eriksson M, Pettersson L, Ullén A, Lumen N, Enblad G, Thellenberg Karlsson C, Jänes E, Sandzén J, Schatteman P, Nyre Vigmostad M, Olsson M, Ghysel C, Sautois B, De Roock W, Van Bruwaene S, Anden M, Verbiene I, De Maeseneer D, Everaert E, Darras J, Aksnessether BY, Luyten D, Strijbos M, Mortezavi A, Oldenburg J, Ost P, Eklund M, Grönberg H, Lindberg J
Nat Med 2024 Nov;30(11):3291-3302

Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis.
Mayrhofer M, De Laere B, Whitington T, Van Oyen P, Ghysel C, Ampe J, Ost P, Demey W, Hoekx L, Schrijvers D, Brouwers B, Lybaert W, Everaert E, De Maeseneer D, Strijbos M, Bols A, Fransis K, Oeyen S, van Dam PJ, Van den Eynden G, Rutten A, Aly M, Nordström T, Van Laere S, Rantalainen M, Rajan P, Egevad L, Ullén A, Yachnin J, Dirix L, Grönberg H, Lindberg J
Genome Med 2018 Nov;10(1):85

The interaction of phospholipase A2 with micellar interfaces. The role of the N-terminal region.
van Dam-Mieras MC, Slotboom AJ, Pieterson WA, de Haas GH
Biochemistry 1975 Dec;14(25):5387-94

Androgen Receptor Burden and Poor Response to Abiraterone or Enzalutamide in TP53 Wild-Type Metastatic Castration-Resistant Prostate Cancer.
De Laere B, Rajan P, Grönberg H, Dirix L, Lindberg J, 
JAMA Oncol 2019 Jul;5(7):1060-1062