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15 November, 2022Joanna Zawacka-Pankau - new docent at MedH
Congratulations to Joanna Zawacka-Pankau who has been appointed docent in Medical Biotechnology with focus on Biochemistry at the Department of Medicine, Huddinge (MedH).
Medicin, Huddinge, Centrum för Infektionsmedicin, Hematologi
14 March, 2022Spider silk can stabilise cancer-suppressing protein
The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet have now found an unusual way of stabilising the protein and making it more potent. By adding a spider silk protein to p53, they show that it is possible to create a protein that is more stable and capable of killing cancer cells. The study is published in the journal Structure.
18 February, 2022Up-scaling of a sustainable spinning method for artificial spider silk
Spider silk is Nature’s high-performance fiber as it combines high tensile strength and large extensibility. A research group at Karolinska Institutet has developed a new and scalable method for producing spider silk proteins and are aiming to scale up the spinning process. Sustainable alternatives to petroleum-based products are needed since the environmental pollution caused by the exploitation of these limited resources is significant.
Researchers at Karolinska Institutet have developed a detailed molecular atlas of the fetal development of the brain. The study published in the top journal Nature is based on so-called single-cell technology and has been done on mice. In this way, researchers have identified almost 800 different cells that are active during fetal development – many times more than previously known.
25 May, 2020New method reveals where DNA is at risk in the cell
Researchers at Karolinska Institutet have developed a new sequencing method that makes it possible to map how DNA is spatially organised in the cell nucleus – revealing which genomic regions are at higher risk of mutation and DNA damage. The technique is described in an article published in the scientific journal Nature Biotechnology.
13 January, 2020Research programmes for groundbreaking treatment and diagnosis
Two new research programmes focusing on AI and bioelectronic medicine, for application in the areas of breast cancer and inflammatory disease, respectively, have been adopted at MedTechLabs. An interdisciplinary centre run by KTH, Karolinska Institutet and the Stockholm Region.
30 September, 2019New method provides vehicles for RNA vaccines
A new way of producing nanoparticles that can function as carriers in so-called mRNA vaccines has been developed by researchers at the Hong Kong node of Karolinska Institutet – the Ming Wai Lau Centre for Reparative Medicine – and the MIT, USA. Using the method, which is described in the scientific journal Nature Biotechnology, the researchers have identified a new class of carrier molecules that inhibit tumour growth and prolong survival in mouse models of cancer.
25 September, 2019Improved mapping of Swedish genes
People – or more specifically just Swedes – are more like chimpanzees than previously known. This is indicated in a genetic mapping of one thousand Swedish individuals, where new DNA sequences that should be included in the reference genome have been identified. The study is published in the scientific journal Molecular Biology and Evolution.
11 June, 2018Genome-editing tool could increase cancer risk
24 June, 2015Artifical neuron mimicks function of human cells
11 May, 2015Ion pump gives the body its own pain alleviation
6 July, 2009One step closer to an artificial nerve cell