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In recent years, the treatment landscape for solid tumors has undergone a notable change. With new cancer treatments, the future looks brighter for many young cancer patients, making fertility issues and future family planning an important aspect. Six specialists in oncology and onco-fertility at the Department of Oncology-Pathology join forces to compile knowledge and recommendations on this important issue.

Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumours, a new study from Karolinska Institutet published in The Journal of Clinical Investigation shows. The discovery corroborates the idea that dietary supplements containing antioxidants can accelerate tumour growth and metastasis.

Analysing all the proteins that exist in a tissue type (the so-called proteome) can provide vital information on the causes of diseases and how they can best be treated. We talk to Janne Lehtiö, professor at the Department of Oncology-Pathology, about proteome-based medicine and what it can contribute to personalised cancer therapy.

A comprehensive comparison of cancer survival between the Nordic countries shows improvements for all countries over time with previously observed differences attenuated. The reasons for these improvements are likely multifactorial. Previous studies comparing cancer survival between the Nordic countries have found marked differences, with a notably poorer survival in Danish patients.

Patients with low income have a higher risk of death following surgery for lung cancer compared with patients with high income. The association remains even after taking prevalence of common comorbidities, and other factors that are known to influence the risk of death, into account. This is according to a study published in the journal Thorax by researchers at Karolinska Institutet in Sweden.

Lung cancer remains the leading cause of cancer-related deaths globally, and this is often due to late detection, leading to the inability to receive curative treatment. Researchers from KI, Karolinska University Hospital and Umeå University have made strides in identifying pre-diagnostic symptoms and sensations of significance for the identification of primary lung cancer.

Lung cancer cells use antioxidants, endogenous or dietary, to spread in the body by activating a protein called BACH1 and increasing the uptake and use of sugar, Swedish and American researchers report in two independent studies. The studies, which are published in the eminent scientific journal Cell, pave the way for new therapeutic strategies for lung cancer.

The day of the week on which a patient has a lung cancer operation has no significance for their survival. This has been demonstrated by researchers at Karolinska Institutet in a new study published in the journal Chest.