Published: 2016-06-08 14:28 | Updated: 2019-05-10 12:29

Newly discovered mechanism may restrict breast cancer growth

Charlotte Rolny and colleagues at the Department of Oncology-Pathology have discovered a new mechanism that could be the key to a new strategy to restrict breast cancer growth.

This mechanism means that the anti-tumor macrophages can be selectively expanded in the tumor while growth of tumorigenic macrophage are restricted.

In the study, the expansion of tumor-suppressing macrophages stimulated cytotoxic white blood cells, so called "killer cells", to kill breast tumor cells.

Read the full study:

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages