Published: 08-06-2016 14:28 | Updated: 10-05-2019 12:29
Newly discovered mechanism may restrict breast cancer growth
Charlotte Rolny and colleagues at the Department of Oncology-Pathology have discovered a new mechanism that could be the key to a new strategy to restrict breast cancer growth.
This mechanism means that the anti-tumor macrophages can be selectively expanded in the tumor while growth of tumorigenic macrophage are restricted.
In the study, the expansion of tumor-suppressing macrophages stimulated cytotoxic white blood cells, so called "killer cells", to kill breast tumor cells.
Read the full study:
Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages