New potential therapeutic target for ovarian cancer
A subset of immune cells called gamma delta T cells are associated with increased survival in patients with advanced ovarian cancer, researchers at Karolinska Institutet report in the scientific journal Science Translational Medicine. The findings suggest that promoting gamma delta T cell responses may be a therapeutic option for ovarian cancer, researchers say.
“Characterization of ascites- and tumor-infiltrating gd T cells reveals distinct repertoires and a beneficial role in ovarian cancer”. Emelie Foord, Lucas C. M. Arruda, Ahmed Gaballa, Charlotte Klynning, Michael Uhlin. Science Translational Medicine, online 20 January 2021, doi: 10.1126/scitranslmed.abb0192.