Lectures and seminars StratRegen Seminar Series with Lars Velten

19-11-2025 12:00 pm Add to iCal
Campus Solna Peter Reichard lecture hall, 3rd floor, Biomedicum

Welcome to a new seminar in the StratRegen Lunch Seminar Series on Wednesday 19th of November 2025, 12.00-13.00 in Peter Reichard lecture hall, Biomedicum, Campus Solna.

Lars Velten
Lars Velten, BIST

Title: Functional genomics of blood formation: Epimutational lineage tracing & synthetic enhancers

 

Speaker: Lars Velten, Group Leader, Center for Genomic Regulation (CRG), Barcelona

Lars Velten lab website

 

 

Publications

Clonal tracing with somatic epimutations reveals dynamics of blood ageing.
Scherer M, Singh I, Braun MM, Szu-Tu C, Sanchez Sanchez P, Lindenhofer D, Jakobsen NA, Körber V, Kardorff M, Nitsch L, Kautz P, Rühle J, Bianchi A, Cozzuto L, Frömel R, Beneyto-Calabuig S, Lareau C, Satpathy AT, Beekman R, Steinmetz LM, Raffel S, Ludwig LS, Vyas P, Rodriguez-Fraticelli A, Velten L
Nature 2025 Jul;643(8071):478-487

Design principles of cell-state-specific enhancers in hematopoiesis.
Frömel R, Rühle J, Bernal Martinez A, Szu-Tu C, Pacheco Pastor F, Martinez-Corral R, Velten L
Cell 2025 Jun;188(12):3202-3218.e21

Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia.
Beneyto-Calabuig S, Merbach AK, Kniffka JA, Antes M, Szu-Tu C, Rohde C, Waclawiczek A, Stelmach P, Gräßle S, Pervan P, Janssen M, Landry JJM, Benes V, Jauch A, Brough M, Bauer M, Besenbeck B, Felden J, Bäumer S, Hundemer M, Sauer T, Pabst C, Wickenhauser C, Angenendt L, Schliemann C, Trumpp A, Haas S, Scherer M, Raffel S, Müller-Tidow C, Velten L
Cell Stem Cell 2023 May;30(5):706-721.e8

Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.
Triana S, Vonficht D, Jopp-Saile L, Raffel S, Lutz R, Leonce D, Antes M, Hernández-Malmierca P, Ordoñez-Rueda D, Ramasz B, Boch T, Jann JC, Nowak D, Hofmann WK, Müller-Tidow C, Hübschmann D, Alexandrov T, Benes V, Trumpp A, Paulsen M, Velten L, Haas S
Nat Immunol 2021 Dec;22(12):1577-1589

 

Sandwiches and coffee will be provided.

Host

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Enric Llorens Bobadilla

Assistant Professor
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Elif Eroglu

Principal Researcher

StratRegen supports researchers, research programs and infrastructure at the Karolinska Institutet (KI) within the field of stem cells and regenerative medicine based on scope, quality, and the potential to strengthen and develop the field.