Lectures and seminars StratRegen Seminar Series with Francesca Spagnoli
Welcome to a new seminar in the StratRegen Lunch Seminar Series on Wednesday the 17th of June 2026, 12.30-13.30 in seminar room Ragnar Granit, Biomedicum, Campus Solna.

Title: Mapping progenitor niche dynamics for regulation of cell fate
Speaker: Professor Francesca Spagnoli, King’s College London
Publications
Understanding development and cellular plasticity in the pancreas in health and disease.
Torres-Cano A, Spagnoli FM
Nat Rev Gastroenterol Hepatol 2026 May;():
Spatially organized cellular communities shape functional tissue architecture in the pancreas.
Torres-Cano A, Darrigrand JF, Herrera-Oropeza G, Goss G, Willnow D, Salowka A, Ma S, Chitnis D, Rouault M, Vigilante A, Spagnoli FM
Sci Adv 2025 Nov;11(46):eadx5791
Heterozygous missense variant in GLI2 impairs human endocrine pancreas development.
Mueller LM, Isaacson A, Wilson H, Salowka A, Tay I, Gong M, Elbarbary NS, Raile K, Spagnoli FM
Nat Commun 2024 Mar;15(1):2483
Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner.
Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM
Dev Cell 2024 Feb;59(3):326-338.e5
Development of a 3D atlas of the embryonic pancreas for topological and quantitative analysis of heterologous cell interactions.
Glorieux L, Sapala A, Willnow D, Moulis M, Salowka A, Darrigrand JF, Edri S, Schonblum A, Sakhneny L, Schaumann L, Gómez HF, Lang C, Conrad L, Guillemot F, Levenberg S, Landsman L, Iber D, Pierreux CE, Spagnoli FM
Development 2022 Feb;149(3):
Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Willnow D, Benary U, Margineanu A, Vignola ML, Konrath F, Pongrac IM, Karimaddini Z, Vigilante A, Wolf J, Spagnoli FM
Nature 2021 Sep;597(7874):87-91
Sandwiches and coffee will be provided.
Host
Enric Llorens Bobadilla
Assistant ProfessorElif Eroglu
Principal ResearcherStratRegen supports researchers, research programs and infrastructure at the Karolinska Institutet (KI) within the field of stem cells and regenerative medicine based on scope, quality, and the potential to strengthen and develop the field.
