Lectures and seminars SRP Diabetes Seminar: “Destickifying Ceramides to Treat Cardiometabolic Disease"

Sphingolipids such as ceramides regulate nutrient homeostasis and contribute to the chronic diseases associated with obesity and dyslipidemia, including diabetes and its complications. The Summer labs investigates the tissue-specific effects of sphingolipids in the regulation of metabolism, the intracellular targets that mediate their effects, and the regulatory events controlling their accumulation. Moreover, they seek to develop drugs targeting enzymes in the ceramide-synthesizing pathway, which hold enormous potential in a broad spectrum of metabolic disorders associated with obesity.

Host: Anna Krook (anna.krook@ki.se)