Lectures and seminars HERM/KiSS seminar - Dr. Joshua Tan: “Discovering rare antibodies to combat malaria"

03-09-2026 3:00 pm - 4:00 pm Add to iCal
Campus Flemingsberg Gene in Neo, Blickagången 16/Online

We are happy to invite you to a joint HERM/KiSS seminar by Dr. Joshua Tan (NIAID, NIH, Bethesda, MD, USA), who will illustrate the fascinating intricacies of human monoclonal antibodies to infectious diseases.

Title

Discovering rare antibodies to combat malaria

Speaker

Joshua Tan, Ph.D., is a Senior Investigator and Chief of the Antibody Biology Unit at the National Institute of Allergy and Infectious Diseases, National Institutes of Health. He received his Ph.D. from the University of Oxford. His research focuses on dissecting the human antibody response to infectious pathogens at the monoclonal level, with pathogens studied including Plasmodium falciparum, infectious viruses and Mycobacterium tuberculosis. Recent work from his group includes the identification of the pGlu-CSP epitope as a target of protective antibodies on the sporozoite surface.

Host

Antonino Cassotta, HERM, MedH, KI.

Attend on site

The talk will be in the seminar room “Gene” in the Neo Building (campus Flemingsberg), followed by a reception by Waters Biosciences (formerly BD Biosciences)

Attend online

To attend online, please contact  - in good time - Antonino Cassotta at HERM. A Zoom link will be provided by email before the seminar.

Please note that the Zoom link will only be forwarded to email addresses that indicate affiliation to a higher educational institution such as a university.

Selected publications (‪‪Google Scholar):

  1. Dacon, C., R. Moskovitz, et al., ... J. Tan (2025). "Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein." Science 387(6729): eadr0510.
  2. Wang LT, Cooper AJR, Farrell B, et al., ... J. Tan (2024). Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5. Cell 187, 4981-4995.e14. 
  3. Tan, J. (2023). "Searching for common ground." Science 379(6633): 655.
  4. Dacon, C., C. Tucker, L. Peng, C. D. Lee, et al., ... J. Tan (2022). "Broadly neutralizing antibodies target the coronavirus fusion peptide." Science 377(6607): 728–735.
  5. Tan, J., B. K. Sack, D. Oyen, I. Zenklusen, L. Piccoli, et al., ... C. Daubenberger, I. Wilson, A. Lanzavecchia (2018). "A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein." Nature Medicine 24(4): 401–407.
  6. Tan, J., K. Pieper, L. Piccoli, et al., ... P. Bull and A. Lanzavecchia (2016). "A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens." Nature 529(7584): 105–109.