Lectures and seminars Faculty event: Martin Eklund

Title

Adaptive platform trials for navigating uncharted territory: Examples from breast- and prostate cancer precision oncology

Abstract

Adaptive platform trials provide a flexible framework for evaluating multiple interventions while allowing designs to evolve as evidence accumulates. This talk introduces the core principles of platform trials and outcome adaptiveness, alongside key statistical, operational, and interpretational caveats. The concepts are illustrated using examples from precision oncology, including adaptive trials in metastatic prostate cancer and personalized breast cancer screening, as well as recent platform trials beyond oncology. Together, these examples illustrate how adaptive designs can help navigate uncharted territory in the precision medicine era.

Short Bio

Martin Eklund is professor of epidemiology at the Department of Medical Epidemiology and Biostatistics where he is focusing his research on reducing the mortality of breast- and prostate cancer as well as the negative side effects of today’s imprecise diagnostics and treatment selection.

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Join the faculty event in Wargentin! After the seminar, the faculty lunch will be served in Ljusgården. The faculty lunches are intended for employees at MEB, and a monthly net salary deduction of 260 SEK will be made for those who work here 20% or more. If you have any questions about the lunch or specific dietary needs due to allergies, etc., please contact internservice@meb.ki.se. If you won’t be participating in the lunches for all or part of the spring term, our new routine is that you need to contact hr-support@meb.ki.se at the start of a new term, to be removed from the list. Retroactive adjustments will not be possible.  

Please, check the labeling on the salads not to take special diet foods that were pre-ordered by your colleagues.