Lectures and seminars Faculty event: Elisavet Syriopoulou

Title

Evaluating mediator interventions for time-to-event outcomes: a causal framework for studying cancer survival differences

Abstract

Survival after a cancer diagnosis varies substantially across population subgroups, and understanding these disparities often requires assessing how potential interventions on key mediators could shift outcomes. While traditional approaches with natural effects have focused on uncovering mechanistic pathways, despite the presence of ill-defined interventions, recent developments have introduced interventional effects that map target trials and focus on evaluating shifts in mediator distributions. This presentation outlines how these interventional effects can be adapted for cancer registry data to evaluate a range of questions, including interventions on single mediators, joint interventions on multiple mediators, and sequential interventions applied in a defined order. The focus will be on concepts and not the underlying mathematics to promote understanding and discussion.

Short Bio

Elisavet Syriopoulou is Assistant Professor of Biostatistics at MEB. Betty works on survival analysis and in particular on the development and application of statistical methods for cancer registry data. Her research consists of two broad areas: understanding the determinants that drive inequalities in cancer survival and improving the reporting and communication of complex cancer statistics. 

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Join the faculty event in Wargentin! After the seminar, the faculty lunch will be served in Ljusgården. The faculty lunches are intended for employees at MEB, and a monthly net salary deduction of 260 SEK will be made for those who work here 20% or more. If you have any questions about the lunch or specific dietary needs due to allergies, etc., please contact internservice@meb.ki.se. If you won’t be participating in the lunches for all or part of the spring term, our new routine is that you need to contact hr-support@meb.ki.se at the start of a new term, to be removed from the list. Retroactive adjustments will not be possible.  

Please, check the labeling on the salads not to take special diet foods that were pre-ordered by your colleagues.