Lectures and seminars Faculty event: David Bergman, Carole Marxer, Soran Bozorg Rabin

Title 1

David Bergman: Menopausal hormone therapy is a risk factor for microscopic colitis

Abstract

This study investigates the association between menopausal hormone therapy (MHT) and microscopic colitis (MC) in postmenopausal women. Conducted as a nationwide, matched case-control study using the ESPRESSO cohort in Sweden, the study explores previous use of MHT among MC patients compared to controls and examines potential dose-response relationships. The findings suggest a significant association between MHT and MC, highlighting the need for further mechanistic studies to clarify the role of estrogen in MC pathogenesis. Physicians prescribing MHT should be aware of this association and consider MC when gastrointestinal symptoms arise in women receiving MHT.

Title 2

Carole Marxer: Adverse pregnancy and birth outcomes in women with biopsy-proven MASLD
 

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) has been linked to an increased risk of adverse pregnancy outcomes. This nationwide cohort study in Sweden examines the long-term impact of MASLD on pregnancy and birth outcomes, comparing women with biopsy-proven MASLD to matched reference births. The study investigates the prevalence of preterm birth, cesarean section, and other adverse outcomes, considering the roles of obesity, familial factors, and disease severity. The findings underscore the importance of monitoring and managing MASLD in pregnant women to mitigate risks and improve maternal and neonatal health.

Title 3

Soran Rabin Bozorg: Association of Disease Activity in Microscopic Colitis with Healthcare Costs and Work Loss
 

Abstract

Microscopic colitis (MC) is a chronic disease associated with watery diarrhea, urgency, and fecal incontinence. This study aims to investigate the economic impact of MC, focusing on healthcare costs and work loss. Utilizing nationwide real-world data from Sweden, the study categorizes MC patients based on disease activity and compares societal costs, including outpatient visits, hospitalizations, medications, and work loss, to general-population comparators. The findings reveal significant differences in costs driven by disease activity, emphasizing the need for improved treatment and symptom control to reduce the economic burden and enhance patient wellbeing.

Faculty lunch

Join the faculty event in Wargentin! After the seminar, the faculty lunch will be served in Ljusgården. The faculty lunches are intended for employees at MEB, and a monthly net salary deduction of 260 SEK will be made for those who work here 20% or more. If you have any questions about the lunch or specific dietary needs due to allergies, etc., please contact internservice@meb.ki.se. If you won’t be participating in the lunches for all or part of the spring term, our new routine is that you need to contact hr-support@meb.ki.se at the start of a new term, to be removed from the list. Retroactive adjustments will not be possible.  

Please, check the labeling on the salads not to take special diet foods that were pre-ordered by your colleagues.