Lectures and seminars Faculty event: Camila Olarte Parra
Speaker: Camila Olarte Parra, post doc at the Unit of Epidemiology, IMM
Title
Combining information from trial participants and non-participants in registry-based randomized trials
Abstract
Combining information from trial participants and non-participants in registry-based trials
The strengths of randomised trials for estimating treatment effects are well understood, but trials often enroll selected populations and have high cost. These drawbacks can be overcome by designing trials nested in registries and using the registry infrastructure to collect information on both trial participants and non-participants. Here, we discuss different sets of assumptions that allow combining information from trial participants and non-participants in registry-based trials to estimate the treatment effect, considering selection into the trial, assignment into treatment groups and adherence to the assigned treatment. We propose estimators that jointly use data from trial participants and non-participants under the different sets of assumptions and illustrate them using data from a major cardiovascular trial nested in the SWEDEHEART registry.
About the speaker
Camila Olarte Parra is a postdoctoral researcher in the CAUSALab at the Unit of Epidemiology in IMM. She was trained as a medical doctor, has a Masters in Epidemiology and a PhD in Statistical Data Analysis. Her research interests include causal inference methodology, causal language, registry-based studies and the estimand framework.
***
Join the faculty event in Wargentin! After the seminar, the faculty lunch will be served in Ljusgården. The faculty lunches are intended for employees at MEB, and a monthly net salary deduction of 260 SEK will be made for those who work here 20% or more. If you have any questions about the lunch or specific dietary needs due to allergies, etc., please contact internservice@meb.ki.se. If you won’t be participating in the lunches for all or part of the spring term, our new routine is that you need to contact hr-support@meb.ki.se at the start of a new term, to be removed from the list. Retroactive adjustments will not be possible.