Stockholm scores high quality rating for societal and patient benefit of its clinical research
Region Stockholm has been given a high-quality rating by the Swedish Research Council (VR) in its evaluation of the quality of clinical research and how it is transformed into patient and societal benefit. The evaluation is important in many respects, including to the distribution of government ALF (Agreement on Clinical Research and Training) funds.
Grants, Prizes and Donations
Three KI researchers awarded ERC Advanced Grants
Three professors at Karolinska Institutet – Gonçalo Castelo-Branco, Maria Eriksson and Björn Högberg – have been awarded ERC Advanced Grants, one of the most prestigious and competitive EU funding schemes. The funds, totaling more than 8 million euros, will support the use of innovative basic research methods to further our understanding of disease mechanisms and to explore the tiniest building blocks of DNA.
Swedish Cancer Society grants SEK 54.9 million to KI researchers
Thirteen researchers at Karolinska Institutet have been awarded 54.9 million Swedish kronor from the Swedish Cancer Society. The foundation is distributing a total of SEK 124.3 million to 31 cancer researchers in Sweden.
Millions to KI researchers for kidney research
Eighteen kidney researchers at Karolinska Institutet have been allocated grants totaling 3.2 million Swedish kronor from the Swedish Kidney Foundation, an announcement made in connection with World Kidney Day on March 9.
KI role model for equality in EU – now awarded for its long-term work
Karolinska Institutet has been awarded a new EU prize for its long-term commitment to gender equality in higher education. The prize of 100,000 euro is the result of nearly 40 years of sustained activity to advance equal opportunities. The efforts have paid off and now KI is recognized as a role model for equality, a “Gender Equality Champion.”
Funding for global study on HPV-burden among girls and women
Several KI researchers are part of an international project that has been awarded nearly $15 million from the Bill & Melinda Gates Foundation, with $1 million co-funding from the Swedish government. The project involves a multi-country study to better understand the burden of Human papillomavirus (HPV) among girls and women in low and lower middle-income countries.
T cells in blood secrete a substance that affects blood pressure and inflammation
Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, KI researchers have discovered that certain T cells in human blood can produce acetylcholine, which may help regulate blood pressure and inflammation. The study, which is published in PNAS, also demonstrates a possible association between these immune cells in seriously ill patients and the risk of death.
Sepsis - The hidden killer
Sepsis has a way of flying under the radar. Public awareness of the life-threatening disease is low, and official statistics are misleading. Now researchers are using special alarm systems, rapid tests and AI to increase detection. Read an in-depth feature series from KI's popular science magazine Medicinsk Vetenskap.
“We-spirit” at the installation of KI’s new president
Training the medical professionals of the future. Facilitating groundbreaking research. And working towards a knowledge-based society enriched by academic freedom. It’s a major undertaking that Annika Östman Wernerson shoulders as Karolinska Institutet’s 24th president. But she won’t be doing it alone – everyone at the university will have to do their bit.
Blind people sense their heartbeats better than sighted
Blind people are better at sensing their own heartbeats than sighted, shows a study by researchers at Karolinska Institutet and Jagiellonian University in Poland. The study indicates that blindness leads to a heightened ability in feeling signals from the inner body.
Risk of cervical cancer twice as high in women with mental illness
Women with mental illness, neuropsychiatric disability, or substance abuse are less likely to go for gynaecological smear tests for cervical cancer and run more than twice the risk of developing the disease, according to a new KI study.
Use of melatonin linked to decreased self-harm in young people
Medical sleep treatment may reduce self-harm in young people with anxiety and depression, an observational study from KI suggests. The risk of self-harm increased in the months preceding melatonin prescription and decreased thereafter.
Many patients are given unnecessary care – here’s why
Caregivers want patients to feel cared for. This, according to a new doctoral thesis from Karolinska Institutet, is one reason why they still give treatments that provide no benefit.
KI well positioned in several areas in QS subject rankings
Karolinska Institutet maintains a strong position in several areas in QS (Quacquarelli Symonds) international subject rankings for universities. In the subject area Medicine, KI is ranked number seven globally, up from number twelve last year.
Now local hospitals can determine how AI systems would detect breast cancer
KI researchers have led the development of a validation platform for assessing how well AI systems detect signs of breast cancer.
Higher risk of dementia in Swedish top-division football players
Men who played football (soccer) in the Swedish top division until the mid 1900s had a higher risk of dementia than men from the general population, a new study from Karolinska Institutet published in The Lancet Public Health reports.
In memory of Barbro Westerholm M.D.
Barbro Westerholm passed away on 13 March. She was born in Stockholm in 1933 and graduated with a medical degree from Karolinska Institutet in 1959. She then went on to earn her PhD in 1964 before becoming a docent at KI. She is known for her engagement with HBTQI issues and the elderly, the “year-rich”.
New technology maps where and how cells read their genome
A new study published in Nature reports that a technology known as spatial omics can be used to map simultaneously how genes are switched on and off and how they are expressed in different areas of tissues and organs.
Common cold gives children immunity against COVID-19
During the pandemic, it became clear that children who contracted COVID-19 became less ill than adults. One hypothesis has been that common colds would give children immunity protecting against a severe form of the disease. Researchers at Karolinska Institutet are now able to show that OC43, one of the coronaviruses that cause common colds, boosts the immune response to COVID-19.
Antibodies in the airways provide durable protection against SARS-CoV-2
High levels of mucosal IgA antibodies in the airways protect against SARS-CoV-2 infection for at least eight months. A new study published in The Lancet Infectious Diseases by researchers at Karolinska Institutet and Danderyd Hospital raises further hope for the feasibility of future nasal vaccine platforms.
New findings on how to avert excessive weight loss from COVID-19
Losing too much weight when infected with COVID-19 has been linked to worse outcomes. Now, researchers at Karolinska Institutet have discovered that SARS-CoV-2 infection fuels blood vessel formation in fat tissues, thus revving up the body’s thermogenic metabolism. Blocking this process by using an existing drug curbed weight loss in mice and hamsters that were infected with the virus.
Researchers may have found a new biomarker for acute COVID-19
Researchers at Karolinska Institutet have shown that patients with acute COVID-19 infection have increased levels of the cytokine IL-26 in their blood. Moreover, high IL-26 levels correlate with an exaggerated inflammatory response that signifies severe cases of the disease. The findings, which are presented in Frontiers in Immunology, indicate that IL-26 is a potential biomarker for severe COVID-19.
New Omicron subvariant largely evades neutralizing antibodies
A study at Karolinska Institutet shows that the coronavirus variant BA.2.75.2, an Omicron sublineage, largely evades neutralizing antibodies in the blood and is resistant to several monoclonal antibody antiviral treatments. The findings, published in the journal The Lancet Infectious Diseases, suggest a risk of increased SARS-CoV-2 infections this winter, unless the new updated bivalent vaccines help to boost immunity in the population.
Immune cell gives possible explanation for sex differences in pancreatic cancer
Immunotherapy for pancreatic cancer has limited effect and differs between men and women. KI researchers have now found a possible explanation for this sex difference.
New treatment can improve cardiac pump function in patients with heart failure
A clinical study by researchers at Karolinska Institutet and Karolinska University Hospital shows that the hunger hormone ghrelin can increase the heart’s pump capacity in patients with heart failure.
Regional ECT, lithium, and clozapine use linked to lower suicide rates in male adolescents
A new KI study suggests that electroconvulsive therapy (ECT), lithium, and clozapine may reduce suicide rates in adolescent men with severe mental illness, consistent with previous findings in adults.
How false vaccine rumours take hold
Rumours spread faster than ever nowadays thanks to social media, and it is easy to get carried away. Some people are also inherently more vulnerable to conspiracy theories. However, sceptics’ concerns should be addressed, not dismissed, say researchers who are studying people’s willingness to take different kinds of vaccines.
Air pollution linked to higher risk of long COVID in young adults
Young adults who lived in highly polluted areas were more likely to suffer from long COVID compared to those living in areas with low levels of pollution, according to a new study by KI researchers published in the Lancet Regional Health – Europe and highlighted in The Conversation.
Kourtney Kardashian’s ‘vaginal health gummies’: here’s what the evidence shows
Even if KI researcher Ina Schuppe Koistinen fully agree with Kourtney Kardashian that vaginal health is an important but not sufficiently talked about part of women’s wellbeing, the two have a strikingly different view on how to tackle the problem.
Beta blockers may reduce the risk of violence
A KI study found that beta blockers, a commonly used heart medication, is linked to lower rates of violence. When people were taking beta blockers they had a 13 percent lower risk of being charged with a violent crime by the police and an 8 percent lower risk of being hospitalized for mental health problems.
Genetics a major factor in the little-known eating disorder Afrid
A twin study from Karolinska Institutet places Arfid among the most heritable of mental disorders. Read researcher Lisa Dinkler’article about the findings in The Conversation.
More articles from KI researchers published in The Conversation
From cold-resistant genes to face masks, Karolinska Institutet researchers contribute to the global public discourse on a range of topics through our collaboration with the international news site The Conversation.
New career path created for research infrastructure specialists
As of April 1 there is a new career path available at KI for research infrastructure specialists, possibly the first of its kind in Sweden.
New university management
KI's new president - the kidney specialist with a passion for education
The new president of Karolinska Institutet, Annika Östman Wernerson, is professor of kidney and transplant science and has a passion for pedagogy research. KI’s internal culture, strengthening the dialogue between management, departments, staff and students, is one of her strongest driving forces.
KI’s new vice-president – the cancer researcher with the empirical mindset
KI’s vice-president is Martin Bergö, a professor of molecular medicine whose most significant discovery to date is that antioxidants can accelerate tumour growth. He aims for a research-inspired leadership, and will start by tuning into the voice of the university and channelling the collective wealth of ideas to make KI even better.
Ole Petter Ottersen on his time as KI’s president
Ole Petter Ottersen has been president of Karolinska Institutet for five and a half years. At the end of this month, February 2023, he will be leaving his office for the last time. Of all he has seen and done, he remembers especially the day when the WHO declared COVID-19 a pandemic.
App resulted in better dietary habits and less screen time in young children
With the help of a multi-language smartphone app, parents in Sweden were able to give their young children better dietary habits and less screen time, according to a study by KI researchers.
Wilhelmina Hoffman and Fredrik Lundberg made honorary doctors at Karolinska Institutet
Karolinska Institutet has decided to make Wilhelmina Hoffman, specialist in geriatric medicine, and economist Fredrik Lundberg honorary doctors.
Digital twin opens way to effective treatment of inflammatory diseases
Inflammatory diseases have complex disease mechanisms that can differ from patient to patient with the same diagnosis. This means that currently available drugs have little effect on many patients. Using so-called digital twins, researchers at Karolinska Institutet have now obtained a deeper understanding of the “off and on” proteins that control these diseases.
Childhood obesity linked to increased risk of different forms of diabetes in adulthood
Child obesity is linked to increased risk of developing diabetes in adulthood, both autoimmune forms of diabetes and different forms of type 2 diabetes, a new study published in Diabetologia reports.
Internet CBT to prevent child sexual abuse launched in several languages
An online anonymous CBT treatment program for individuals with a sexual interest in children showed good results in an English language pilot study. Now the program developed by KI researchers for crime prevention also opens in Swedish, German, and Portuguese.
Information regarding the war in Ukraine
On this page you will find information for staff and students and resources for journalists and the public concerning Russia’s invasion of Ukraine.
The Macchiarini case: timeline
KI in the debate
KI constantly engages in the public debate and comments on current issues concerning our operations. On this page you find published opinion pieces and comments.
KI in the media (Swedish only)
Research subjects wanted
Selected top publications
Researchers propose a novel biomarker for early diagnosis of Alzheimer's disease
Igor C. Fontana, Amit Kumar, Agneta Nordberg, Nature Reviews Neurology, March 2023
New method identifies protein forms involved in disease and drug response
Nils Kurzawa et al, Nature Chemical Biology, March 2023
Researchers have mapped the human adipose tissue: This is how fat cells change in health and disease
Lucas Massier et al, Nature Communications, March 2023
Less dangerous than previously thought to receive an artificial heart valve that is too small
Michael Dismorr et al, Journal of the American College of Cardiology, March 2023
Too much oxygen after cardiac arrest is associated with lower survival
Akil Awad et al, Critical Care, March 2023
Participation in a clinical trial linked to lower mortality in patients with heart failure
Lars H. Lund et al, European Heart Journal, March 2023
Movement reduces sensory responses in Parkinson’s disease
Roberto de la Torre-Martinez et al, Nature Communications, February 2023
Researchers identify T cells involved in the autoimmune disease AAV
Ravi Kumar Sharma et al, Kidney International, February 2023
More high impact publications