The disappointment that led to a Nobel prize

When Nobel prize winner Michael Kremer initially looked at the data of his now famous 1990s Kenya school study, he felt shocked and disappointed. The data showed that more textbooks did nothing to improve educational outcomes, contrary to what most researchers believed. But rather than succumbing to disillusionment, Kremer dug deeper into Kenya’s schooling system to uncover what measures truly did make an impact and found his answer: targeted help for weak students. On Wednesday, he visited KI.

Study debunks notion that C-section would increase risk of obesity in the child

Women who have C-sections are no more likely to have children who develop obesity than women who give birth naturally, according to a study by researchers at Karolinska Institutet in Sweden published in PLOS Medicine. The findings contradict several smaller studies that did find an association between C-sections and offspring obesity but did not consider the numerous maternal and prenatal factors that the researchers did in this study.

High androgen levels during pregnancy increase the risk of PCOS for several generations

Daughters of women with polycystic ovarian syndrome (PCOS) are five times more likely to be diagnosed with PCOS as adults, and the generational transmission is driven by high androgen levels during pregnancy, researchers at Karolinska Institutet in Sweden report. Their results, which are based on register-based and clinical studies as well as transgenerational animal studies, are published in Nature Medicine.

Pioneers met researchers of the future when KI held conferment ceremony

“Each of you have taken your own path and have done it your way. That reminds me of a classic song,” said Robert Harris before he burst into Frank Sinatra’s ‘My Way’ in a tribute to Karolinska Institutet’s new doctors. With his tenor reverberating across the Blue Hall in Stockholm City Hall, the vice-president of doctoral education elicited laughter and applauds during KI’s annual autumn conferment ceremony held on Friday.

Top-publications list

A limited selection of recent publications in high impact journals where researchers from KI are main authors.
 

Genes predict tamoxifen treatment outcome in breast cancer
CYP2D6 Genotype Predicts Tamoxifen Discontinuation and Prognosis in Patients With Breast Cancer, He, W et al, Journal of Clinical Oncology, Dec. 2019.
 

Contact lens measures eye pressure after transplantation of insulin-secreting cells
Intraocular Pressure Monitoring Following Islet Transplantation to the Anterior Chamber of the Eye, Joohee Kim et al, Nano Letters, Nov 2019.
 

Increased neurogenesis in mice after fecal transplant
Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice, Kundu P et al, Science Translational Medicine, Nov 2019. 
 

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