Published: 23-02-2017 10:20 | Updated: 28-02-2017 12:26

Patients registered in a heart failure registry lived longer

Heart failure patients registered in the Swedish Heart Failure Registry receive better medication and have a 35 percent lower risk of death than unregistered patients, according to a new study from Karolinska Institutet in Sweden. The findings are presented in the European Journal of Heart Failure.

Health quality registries are used for many purposes including to report quality of care and to identify areas for quality improvement. Sweden has been a pioneer in the establishment of quality registries for a broad range of diseases. The Swedish Heart Failure Registry (SwedeHF; RiksSvikt) registers clinical and treatment data for patients with heart failure from most hospitals in Sweden. RiksSvikt is voluntary, so some but not other patients get registered, and this is determined largely by the availability of staff and resources at local hospitals.

Over 200 000 patients

In the current study, a Swedish team comprising researchers at Karolinska Institutet, Linköping University, and Uppsala Clinical Research Center analyzed data from 231,437 patients who were diagnosed with heart failure in Sweden 2006-2013. A comparison between those who were registered in RiksSvikt and those who were not showed that the registered patients had a remarkable 35 percent lower risk of death.

The investment in quality registries in Sweden has provided helpful quality reporting and contributed to improved quality of care, but the concrete health benefits for patients have been less clear.

“Now we also see that in heart failure, quality reporting translates directly into better survival,” says Associate Professor Lars H. Lund at Karolinska Institutet's Department of Medicine who led the study. “It is imperative that the investment in registries from the government, hospitals and clinicians continues to expand, as this will lead to better patient survival”.

More likely to receive medication

Further analyses showed that patients who were registered in RiksSvikt were more likely to receive heart failure medications than unregistered patients, and that this to a large extent explained the difference in survival.

“There are several common treatments for heart failure which are known to cost-effectively reduce the risk of hospitalization and death, but these are underutilized,” says Associate Professor Lars H. Lund.

Heart failure is a common condition in which the heart is unable to pump sufficient quantities of blood around the body. It is the most common cause of hospitalization in Sweden and is associated with a high risk of death.

The study was financed by The Swedish Research Council, The Swedish Heart-Lung Foundation, The Stockholm County Council and AstraZeneca. There are no conflicts of interest declared related to the study. Outside the work submitted, some of the researchers have received research grants, speaker’s fees and/or consulting fees from AstraZeneca, Novartis, Bayer, Vifor Pharma, Relypsa, Boston Scientific, St Jude, Medtronic, HeartWare and Aspen Pharma. One of the researchers is employed as epidemiologist by AstraZeneca.


Association between enrolment in a heart failure quality registry and subsequent mortality – a nationwide cohort study
Lund LH, Carrero J, Farahmand B, Henriksson KM, Jonsson Å, Jernberg T, Dahlström U.
European Journal of Heart Failure, online 23 Feb 2017. doi: 10.1002/ejhf.762