Lectures and seminars Neutrophil–Macrophage Crosstalk Drives Immunosuppression in Glioblastoma
Dolores Hambardzumyan, Icahn School of Medicine at Mount Sinai
Selected Publications
Histone H3K27M variants determine myeloid subset dependencies and immune reprogramming in diffuse midline glioma.
Puigdelloses Vallcorba M, Rawat K, Soni N, DiMauro A, Chu JD, Thomason W, Furtado GC, Strahl M, Wu J, Joshi T, Angione A, Piñero G, Becher OJ, Ross JL, Tsankov AM, Lira SA, Hambardzumyan D
Proc Natl Acad Sci U S A 2026 Aug;123(33):e2537768123
Mismatch repair deficiency drives malignant progression and alters the tumor immune microenvironment in glioblastoma models.
Puigdelloses Vallcorba M, Soni N, Choi SW, Rawat K, Joshi T, Friedman S, Buonfiglioli A, Angione A, Chen Z, Piñero G, Price G, Dedhia M, Roche R, Radkevich E, Bowcock AM, Bhatt D, Edelmann W, Samstein RM, Richardson TE, Tsankova NM, Tsankov AM, Bindra RS, Rabadan R, Vasquez JC, Hambardzumyan D
J Clin Invest 2026 Mar;136(6):
Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations.
Ross JL, Puigdelloses-Vallcorba M, Piñero G, Soni N, Thomason W, DeSisto J, Angione A, Tsankova NM, Castro MG, Schniederjan M, Wadhwani NR, Raju GP, Morgenstern P, Becher OJ, Green AL, Tsankov AM, Hambardzumyan D
Immunity 2024 Nov;57(11):2669-2687.e6
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Contact: Bertrand Joseph