Conferences and symposiums Beyond amyloid and tau: the importance of co-pathologies in Alzheimer's disease

04-11-2024 8:15 am - 5:30 pm Add to iCal
Campus Solna Nobel Forum, Nobels väg 1, Solna
Decorative image illustrating Alzheimer's disease.
Photo: Artur Plawgo, Getty Images/iStockphoto

Welcome to a symposium jointly organised by the Aging Research Center and the Center for Alzheimer Research. The event will also be streamed via Zoom.

Three leading experts on the topic will join us as keynote speakers:

  • Dr. Michelle Mielke, Wake Forest University, USA
  • Dr. Bart de Strooper, VIB-KU Leuven Center for Brain & Disease Research, Belgium; UK Dementia Research Institute, University College London, UK
  • Dr. Clifford R. Jack, Jr., Mayo Clinic College of Medicine, USA

Registration

Register to the symposium no later than 25 October 2024.

Scientific and organizing committee

  • The Aging Research Center (ARC), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet: Giulia Grande, Assistant professor
  • The Center for Alzheimer Research (CAR), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet: Daniel Ferreira, Director and CAR steering group

CAR steering group

  • Per Nilsson, Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet
  • Dorota Religa, Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet
  • Chengxuan Qiu, Division of Aging Research Centre, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet

Supported by

Journal of Internal Medicine (JIM), with co-financing from the Strategic Research Area in Epidemiology and Biostatistics at Karolinska Institutet.

Follow us on social media using #ADcopath24

Programme overview

08:15-08:45

Registration

08:45-09:00

Introduction and welcome to the symposium

  • Maria Ankarcrona, Head of Department of Neurobiology, Care Sciences and Society, KI
  • Bo Angelin, Editor in Chief Journal of Internal Medicine (JIM)
  • Giulia Grande, Assistant Professor at ARC/KI and Daniel Padilla Ferreira, Director of CAR, KI
09:00-11:00

SESSION I

09:00-09:45

Keynote: "Considerations for Implementation of Blood-Based Biomarkers in Primary Care"

Speaker: Michelle Mielke, Wake Forest University, USA

Discussant: Laura Fratiglioni, KI

09:45-10:45

Presentations

  • 09:45–10:05: "Disease burden and blood biomarkers of Alzheimer's disease", Giulia Grande, KI
  • 10:05–10:25: "N-glycans and Alzheimer's disease", Sophia Schedin-Weiss, KI
  • 10:25–10:45: "Kidney disease and Alzheimer's disease", Hong Xu, KI

Discussants: Alessandra Marengoni, KI and University of Brescia, Italy and Dorota Religa, KI

10:45-11:00

Short pannel discussion and concluding remarks from SESSION I

Michelle Mielke, Laura Fratiglioni, Alessandra Marengoni, Dorota Religa.

Discussant: Daniel Ferreira

11:00-11:30

Coffee break

11:30-14:30

SESSION II

11:30-12:15

Keynote: "Transitioning from amyloid plaques to cellular dysfunction in Alzheimer’s disease"

Speaker: Bart de Strooper, VIB-KU Leuven Center for Brain & Disease Research, Belgium; UK Dementia Research Institute, University College London, UK

Discussant: Maria Ankarcrona, KI

12:15-13:15

Lunch

13:15-14:15

Presentations

  • 13:15–13:35: "Mitochondrial function, dynamics and their regulation of astrocyte-neuron crosstalk in Alzheimer´s disease", Luana Naia, KI
  • 13:35-13:55: "Iron deposition, brain stiffness and neuroinflammation", Grégoria Kalpouzos, KI
  • 13:55-14:15: "Cerebrovascular co-pathology in Alzheimer´s disease", Anna Marseglia, KI

Discussants: Pieter Visser, KI and Maastricht University, Amsterdam University Medical Center, The Netherlands and Chengxuan Qiu, KI

14:15-14:30

Short pannel discussion and concluding remarks from SESSION II

Bart De Strooper, Maria Ankarcrona, Pieter Visser, Chengxuan Qiu.

Discussant: Daniel Ferreira

14:30-15:00

Coffee break

15:00-17:00

SESSION III

15:30-16:30

Keynote: "Revised criteria for diagnosis and staging Alzheimer’s disease: convergence across the neurodegenerative disease spectrum"

Speaker: Clifford R. Jack, Jr., Mayo Clinic College of Medicine, USA

Discussant: Maria Eriksdotter, KI

15:45-16:45

Presentations

  • 15:45-16:05: "Lewy body co-pathology in Alzheimer’s disease", Annegret Habich, KI
  • 16.05-16.25 "Complexity of mental health in old age: implications for depression, cognition, and resilience", Serhiy Dekhtyar, KI
  • 16.25-16.45 "Sex hormones and Alzheimer’s disease", Ivan Nalvarte, KI

Discussants: Patrizia Mecocci, KI and University of Perugia, Italy and Per Nilsson, KI

16:45-17:00

Short pannel discussion and concluding remarks from SESSION III

Clifford R. Jack, Jr., Maria Eriksdotter, Patrizia Mecocci, Per Nilsson.

Discussant: Daniel Ferreira

17:00-17:30

Round table and concluding remarks

Michelle Mielke, Bart de Strooper, Clifford R. Jack, Jr., Laura Fratiglioni, Maria Ankarcrona, Maria Eriksdotter.

Discussant: Bengt Winblad, KI