Published: 2020-05-26 10:38 | Updated: 2020-05-26 10:38

New thesis on organ-specific autoimmune diseases

Jakob Skov from the group Experimental and Clinical Neuroendocrinology, Department of Molecular Medicine and Surgery, will defend his thesis "Epidemiological studies on comorbidity, heritability and co-aggregation in organ-specific autoimmune diseases" on June 5, 2020. Main Supervisor is Sophie Bensing.

Jakob Skov
Jakob Skov

What's the main focus of your thesis?

Heritability and etiologic overlap among organ-specific autoimmune diseases with focus on Addison’s disease and autoimmune thyroid diseases. We have also examined cardiovascular comorbidity in Addison’s disease

Which are the most important results?

Women with Addison’s disease are at increased risk of ischemic heart disease. Moreover, the risk of cardiovascular disease correlates with adrenal hormone replacement doses in both women and men.

How can this new knowledge contribute to the improvement of people’s health?

If the correlation between replacement doses and cardiovascular disease reflects a causal relation, cardiovascular morbidity could be reduced by using low replacement doses when possible.

What are your future ambitions?

To combine registry-based research on autoimmune and endocrine diseases with clinical work.

Dissertation

Friday June 5th, 2020 at 09:15. The dissertation seminar can be followed online via Zoom: https://ki-se.zoom.us/j/61721460720 

Thesis

Epidemiological studies on comorbidity, heritability and co-aggregation in organ-specific autoimmune diseases

 

Contact

Jakob Skov Affiliated to research