New thesis on organ-specific autoimmune diseases
Jakob Skov from the group Experimental and Clinical Neuroendocrinology, Department of Molecular Medicine and Surgery, will defend his thesis "Epidemiological studies on comorbidity, heritability and co-aggregation in organ-specific autoimmune diseases" on June 5, 2020. Main Supervisor is Sophie Bensing.
What's the main focus of your thesis?
Heritability and etiologic overlap among organ-specific autoimmune diseases with focus on Addison’s disease and autoimmune thyroid diseases. We have also examined cardiovascular comorbidity in Addison’s disease
Which are the most important results?
Women with Addison’s disease are at increased risk of ischemic heart disease. Moreover, the risk of cardiovascular disease correlates with adrenal hormone replacement doses in both women and men.
How can this new knowledge contribute to the improvement of people’s health?
If the correlation between replacement doses and cardiovascular disease reflects a causal relation, cardiovascular morbidity could be reduced by using low replacement doses when possible.
What are your future ambitions?
To combine registry-based research on autoimmune and endocrine diseases with clinical work.