Lectures and seminars "Unlocking the Genome’s Regulatory Code" with Professor Bing Ren, University of California San Diego

24-05-2024 4:30 pm - 5:30 pm Add to iCal
Campus Solna Eva & Georg Klein lecture hall, Biomedicum, Karolinska Institutet, Solnavägen 9, Solna

Prof. Ren’s research group is interested in understanding how the complex gene regulatory networks in mammalian cells control cellular proliferation and differentiation. The research in the Ren lab is divided into two general areas: 1) the development of genomics and bioinformatics tools that allow genome wide identification of regulatory targets for transcription factors; and, 2) the application of these tools to the study of transcription factors that play critical roles in cancer.

Professor Ben Ring
Professor Ben Ring

Title

"Unlocking the Genome’s Regulatory Code"

Speaker

Professor Bing Ren, University of California San Diego, USA

More information

 http://enhancer.ucsd.edu/renlab_website/

Prof Bing Ren is the opponent of Mukund Kabbes defence the 24 May, read more here

A few recent publications

  • Zu S, Li YE, Wang K, Armand EJ, Mamde S, Amaral ML, Wang Y, Chu A, Xie Y, Miller M, Xu J, Wang Z, Zhang K, Jia BB, Hou X, Li B, Kuan S, Liu H, Zhou J, Pinto-Duarte A, Lucero J, Osteen J, Nunn M, Smith KA, Tasic B, Yao Z, Zeng H, Wang Z, Shang J, Behrens MM, Ecker JR, Wang A, Preissl S, Ren B*, Single-cell analysis of chromatin accessibility in the adult mouse brain. Nature, Dec 14, 2023
     
  • Zemke NR, Armand EJ, Wang W, Lee S, Zhou J, Li YE, Liu H, Tian W, Nery JR, Castanon RG, Bartlett A, Osteen JK, Li D, Zhuo X, Xu V, Chang L, Dong K, Indralingam H, Rink JA, Xie Y, Miller M, Krienen FM, Zhang Q, Taskin N, Ting J, Feng G, McCarroll SA, Callaway EM, Wang T, Lein ES, Behrens MM, Ecker JR*, Ren B*, Conserved and divergent gene regulatory programs of the mammalian neocortex. Nature, Dec 14, 2023, 
     
  • Li YE, Preissl S, Miller M, Johnson ND, Wang Z, Jiao H, Zhu C, Wang Z, Xie Y, Poirion O, Kern C, Pinto-Duarte A, Tian W, Siletti K, Emerson N, Osteen J, Lucero J, Lin L, Yang Q, Zhu Q, Zemke N, Espinoza S, Yanny AM, Nyhus J, Dee N, Casper T, Shapovalova N, Hirschstein D, Hodge RD, Linnarsson S, Bakken T, Levi B, Keene CD, Shang J, Lein E, Wang A, Behrens MM, Ecker JR, Ren B. A comparative atlas of single-cell chromatin accessibility in the human brain. Science. 2023 Oct 13;382(6667):eadf7044. doi: 10.1126/science.adf7044.
     
  • Xie Y, Zhu C, Wang Z, Tastemel M, Chang L, Li YE, Ren B. Droplet-based single-cell joint profiling of histone modifications and transcriptomes. Nat Struct Mol Biol. 2023 Aug 10.
     
  • Yan J*, Qiu Y, dos Santos AMR, Yin Y, Li YE, Vinckier N, Nariai N, Benaglio P, Raman A, Li X, Fan S, Chiou J, Chen F, Frazer KA, Gaulton KJ, Sander M, Taipale J* and Ren B*. Systematic Analysis of Transcription Factor Binding to Noncoding Variants in the Human Genome, Nature 2021 Jan 27. (*co-corresponding author)

 

Contact

Gonçalo Castelo-Branco Professor