Lectures and seminars MBB keynote lectures: Stirling Churchman, professor of Genetics, Harvard Medical School
Welcome to a lecture with Stirling Churchman, a professor of Genetics at Harvard Medical School. Her lab seeks an integrative view of gene regulation to understand where, when, and how genes are controlled using experimental and computational approaches that probe the many steps of gene expression, from transcription to translation in health and disease.
Speaker
Stirling Churchman, a professor of Genetics at Harvard Medical School
Key publications:
Ietswaart R#*, Smalec BM*, Xu A*, Choquet K, McShane E, Jowhar ZM, Guegler CK, Baxter-Koenigs AR, West ER, Fu BXH, Gilbert L, Floor SN#, Churchman LS#. (2024) Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle. Mol Cell, 84, 2765-2784.e16.
McShane E, Couvillion M, Ietswaart R, Prakash G, Smalec BM, Soto I, Baxter-Koenigs AR, Choquet K, Churchman LS. (2024) A kinetic dichotomy between mitochondrial and nuclear gene expression drives OXPHOS biogenesis. Mol. Cell 84, 1541–1555.e11.
Drexler, HL, Choquet K, Merens HE, Tang PS, Simpson JT and Churchman LS. (2021) Revealing nascent RNA processing dynamics with nano-COP. Nat Protoc. 6(3):1343–1375
Bergström & Samuelsson - MBB keynote lectures
We are thrilled to announce a new lecture series celebrating the groundbreaking contributions of MBB’s Nobel Prize winners in Physiology or Medicine in 1982 Sune Bergström and Bengt Samuelsson for their pioneering work on prostaglandins*. This series will feature top speakers from around the world, sharing their latest research and insights in the broad research areas of MBB. The Bergström & Samuelsson MBB keynote lectures will take place at the Nobel Forum and are followed by a mingle with champagne! PhDs and postdocs can sign up for the lunch together with the speaker (12:00-13:15).
*Bergström purified and determined the chemical structure of several prostaglandins, while Samuelsson detailed their formation from fatty acids, particularly arachidonic acid. Their work led to the discovery of important components in the prostaglandin system, including leukotrienes and thromboxanes, which play crucial roles in inflammation, blood clotting, and various other bodily functions. These findings provided essential knowledge about normal body functions and explained mechanisms behind diseases such as allergies, inflammations, and vascular diseases. As a result, their research opened up new avenues for medical treatments, leading to the development of drugs for conditions like asthma and contributing to advancements in reproductive medicine.