Lectures and seminars MBB keynote lectures: Prisca Liberali, Friedrich Miescher Institute for Biomedical Research
Welcome to a lecture with Prisca Liberali, senior group leader at the Friedrich Miescher Institute for Biomedical Research. Her lab applies a systems biology approach to understanding tissue organization using organoid models with high-resolution live-cell imaging to probe the collective properties of multi-cellular systems and how their properties arise from the behavior of individual cells to understand cell reprogramming and disease.
Speaker
Prisca Liberali, Friedrich Miescher Institute for Biomedical Research
Title
“Scaling life: How Single Cells Orchestrate Tissue-Level Coordination”
Key publications:
Moos, F., Suppinger, S., de Medeiros, G., Oost, K., Boni, A., Rémy, C., Weevers, S., Tsiairis, C., Strnad, P., Liberali, P. Open top multisample dual-view light-sheet microscope for live imaging of large multicellular systems. Nature Methods (2024)
Suppinger, S., Zinner, M., Aizarani, N., Lukonin, I., Ortiz, R., Azzi, C., B Stadler, M., Vianello, S., Palla, G., Kohler, H., Mayran, A., P Lutolf, M., Liberali, P. Multimodal characterization of murine gastruloid development. Cell Stem Cell Volume 30, Issue 6, 1 June 2023, Pages 867-884.e11 (2023)
Lukonin I, Serra D, Challet Meylan L, Volkmann K, Baaten J, Zhao, R Meeusen S, Colman K, Maurer F, Stadler MB, Jenkins J, Liberali P. Phenotypic landscape of intestinal organoid regeneration. Nature 586, pages 275–280 (2020)
Bergström & Samuelsson - MBB keynote lectures
We are thrilled to announce a new lecture series celebrating the groundbreaking contributions of MBB’s Nobel Prize winners in Physiology or Medicine in 1982 Sune Bergström and Bengt Samuelsson for their pioneering work on prostaglandins*. This series will feature top speakers from around the world, sharing their latest research and insights in the broad research areas of MBB. The Bergström & Samuelsson MBB keynote lectures will take place at the Nobel Forum and are followed by a mingle with champagne! PhDs and postdocs can sign up for the lunch together with the speaker (12:00-13:15).
*Bergström purified and determined the chemical structure of several prostaglandins, while Samuelsson detailed their formation from fatty acids, particularly arachidonic acid. Their work led to the discovery of important components in the prostaglandin system, including leukotrienes and thromboxanes, which play crucial roles in inflammation, blood clotting, and various other bodily functions. These findings provided essential knowledge about normal body functions and explained mechanisms behind diseases such as allergies, inflammations, and vascular diseases. As a result, their research opened up new avenues for medical treatments, leading to the development of drugs for conditions like asthma and contributing to advancements in reproductive medicine.