Lectures and seminars A pathway to precision lung health using multi-omics
Jessica Ann Lasky-Su, Harvard Medical School
Jessica Ann Lasky-Su, ScD
Associate Professor in Medicine
President, Metabolomics Society
Brigham and Women's Hospital and Harvard Medical School
Dr. Lasky-Su is an Associate Professor in Medicine and Associate Statistician and Epidemiologist at Harvard Medical School and Brigham and Women’s Hospital. Over two decades, Dr. Lasky-Su has focused on the analysis of genetics, genomics, and metabolomics data in large scale human studies, with research areas that include asthma, COVID-19, immune development, and aging. The accumulation of these efforts has resulted in a productive track record of over 200 original research articles. Via multiple PI-funded grants, Dr. Lasky-Su has particularly focused her research on “integrative metabolomics,” that integrates multiomic data while using a metabolomic-centric framework. Lasky-Su is also a leader in national and international metabolomic organizations for metabolomics, including the President of the Metabolomics Society-the largest International society for metabolomics, in the chairman of the NIH’s Consortium of METabolomic Studies (COMETS)-the largest international consortium of metabolomic epidemiological studies.
Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma.
Kachroo P, Stewart ID, Kelly RS, Stav M, Mendez K, Dahlin A, Soeteman DI, Chu SH, Huang M, Cote M, Knihtilä HM, Lee-Sarwar K, McGeachie M, Wang A, Wu AC, Virkud Y, Zhang P, Wareham NJ, Karlson EW, Wheelock CE, Clish C, Weiss ST, Langenberg C, Lasky-Su JA
Nat Med 2022 04;28(4):814-822
Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in Two TOPMed Cohorts.
Kelly RS, Mendez KM, Huang M, Hobbs BD, Clish CB, Gerszten R, Cho MH, Wheelock CE, McGeachie MJ, Chu SH, Celedón JC, Weiss ST, Lasky-Su J
Am J Respir Crit Care Med 2022 02;205(3):288-299
Metabolomic differences in lung function metrics: evidence from two cohorts.
Kelly RS, Stewart ID, Bayne H, Kachroo P, Spiro A, Vokonas P, Sparrow D, Weiss ST, Knihtilä HM, Litonjua AA, Wareham NJ, Langenberg C, Lasky-Su JA
Thorax 2022 Sep;77(9):919-928