Workshop on Organoid & 3D Culturing November 2018
- Stem cells and development (mESC, hESC, hiPSC)
- Organoids from pluripotent stem cells
- Recreating organs from pluripotent stem cells (where are we now?)
- Organoids in neurological disease modeling
- Cells and materials in regenerative medicine
Exciting advancements in cell culture technologies have led to the development of new threedimensional tissue models, known as organoids, that reflect key structural and functional properties of human organs, like Intestinal, hepatic, retinal and pulmonary organoids. Mini-brains (cerebral organoids) are now being used to study brain disorders, such as Alzheimer’s disease, schizophrenia, microcephaly and other brain disorder as well as drug discovery process and regenerative medicine. The development of
organoid culture has a great expectation within the research community to get valuable information in development and disease.
Karolinska Stem Cell & Organoid (KISCO, former MSCU) at KI is constantly working to develop more accurate and scalable organoid culture methods. KISCO has developed a 3D-organiod culture system which utilizes hydrogel encapsulation and use of spinning bioreactors as well as microgravity based rotary wall vessel bioreactor to mimic the natural microenvironment for the brain development. The objective of this workshop is to provide knowledge and information about development in the area of organoids / 3D culture, with focus on cerebral organoids, and support research groups that aim to incorporate reliable and advanced in vitro methods of organoid generation for their ongoing and future research projects.
Organized by Karolinska Stem Cell & Organoid (former Murine Stem Cells Unit) at the Department of Biosciences and Nutrition. Supported by the DEVREG Doctoral Programme.