New thesis on pulmonary resection for malignant tumors
Mamdoh Al-Ameri from the research group Thoracic Surgery will defend his thesis "Pulmonary resection for malignant tumors" on June 8, 2018. Main Supervisor is Ulrik Sartipy.
What is the main focus of your thesis?
My thesis is about pulmonary resection for malignant tumors. Lung cancer and metastasis from colorectal cancer constitute the major part of malignant tumors in the lung. With 5 studies, this thesis reviews important clinical aspects of this surgery in Sweden and Karolinska University Hospital.
What are the most important results?
In study I, we found that physical, but not mental, preoperative self-reported health-related quality of life lower than the reference value was associated with poorer long-term survival in patients undergoing lung surgery. Studies II and III showed that 5-year survival after pulmonary metastasectomy of colorectal cancer in Sweden and Karolinska University Hospital was comparable to the best results from previously published data. We found in study IV that the new surgical technique of minimal invasive lobectomy (VATS) of lung cancer has excellent short and long clinical outcomes. Study V showed no association between weekday and survival in patients operated for lung cancer in Sweden.
How can this new knowledge contribute to the improvement of people’s health?
Preoperative self-reported health-related quality of life can be integrated in the construction of future predictive models to improve clinical decisions in general thoracic surgery.
VATS lobektomi is an alternative to conventional thoracotomy approach in surgical treatment of lung cancer with non-inferior or better short and long term outcomes.
What are your future ambitions?
To continue with research and development of minimal invasive technology in general thoracic surgery and collaborate with other researchers and clinics inside and outside Sweden.